{"id":8765,"date":"2018-03-08T09:44:42","date_gmt":"2018-03-08T02:44:42","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=8765"},"modified":"2018-03-16T09:31:40","modified_gmt":"2018-03-16T02:31:40","slug":"chinh-sua-gen-giup-te-bao-co-the-tim-kiem-va-tieu-diet-khoi-u-ung-thu-nao","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/chinh-sua-gen-giup-te-bao-co-the-tim-kiem-va-tieu-diet-khoi-u-ung-thu-nao\/","title":{"rendered":"Ch\u1ec9nh s\u1eeda gen gi\u00fap t\u1ebf b\u00e0o c\u00f3 th\u1ec3 t\u00ecm ki\u1ebfm v\u00e0 ti\u00eau di\u1ec7t kh\u1ed1i u ung th\u01b0 n\u00e3o"},"content":{"rendered":"

Ung th\u01b0\u00a0l\u00e0 c\u0103n b\u1ec7nh v\u1ed1n \u0111\u00e3 kh\u00f3 trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb th\u00ec\u00a0ung th\u01b0 n\u00e3o\u00a0l\u1ea1i c\u00e0ng kh\u00f3 kh\u0103n h\u01a1n. Tuy nhi\u00ean, m\u1ed9t k\u1ef9 thu\u1eadt m\u1edbi \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u b\u1edfi c\u00e1c nh\u00e0 khoa h\u1ecdc th\u1eafp l\u00ean hy v\u1ecdng v\u1ec1 m\u1ed9t ng\u00e0y n\u00e0o \u0111\u00f3, ch\u00fang ta c\u00f3 th\u1ec3 l\u00e0m ch\u1ee7 v\u1ea5n \u0111\u1ec1 v\u00e0 ch\u1eefa l\u00e0nh c\u0103n b\u1ec7nh n\u00e0y.<\/p>\n

\u0110\u1ed1i v\u1edbi ung th\u01b0 n\u00e3o, m\u1ed9t trong nh\u1eefng d\u1ea1ng ph\u1ed5 bi\u1ebfn nh\u1ea5t ch\u00ednh l\u00e0\u00a0glioblastomas\u00a0– ki\u1ec3u ung th\u01b0 b\u1eaft ngu\u1ed3n t\u1eeb c\u00e1c t\u1ebf b\u00e0o \u0111\u00f3ng vai tr\u00f2 h\u1ed7 tr\u1ee3 trong n\u00e3o. Trung b\u00ecnh, m\u1ed9t ng\u01b0\u1eddi sau khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc glioblastomas s\u1ebd kh\u00f4ng th\u1ec3 s\u1ed1ng s\u00f3t trong v\u00f2ng 15 th\u00e1ng v\u00e0 hi\u1ec7n c\u0169ng c\u00f3 r\u1ea5t \u00edt l\u1ef1a ch\u1ecdn trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb d\u1ea1ng ung th\u01b0 n\u00e0y. Nh\u01b0ng m\u1ecdi chuy\u1ec7n c\u00f3 th\u1ec3 s\u1ebd thay \u0111\u1ed5i khi gi\u00e1o s\u01b0 Gianpietro Dotti \u0111\u1ebfn t\u1eeb \u0110\u1ea1i h\u1ecdc B\u1eafc Carolina v\u00e0 c\u00e1c c\u1ed9ng s\u1ef1 v\u1eeba thu \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 \u0111\u1ea7y h\u1ee9a h\u1eb9n trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u1edf chu\u1ed9t nh\u1edd m\u1ed9t k\u1ef9 thu\u1eadt \u0111\u1eb7c bi\u1ec7t.<\/p>\n

S\u1eed d\u1ee5ng gi\u1ea3i ph\u00e1p\u00a0CAR-T, c\u00e1c nh\u00e0 khoa h\u1ecdc b\u1eaft \u0111\u1ea7u vi\u1ec7c ch\u1eefa tr\u1ecb b\u1eb1ng c\u00e1ch tr\u00edch xu\u1ea5t c\u00e1c\u00a0t\u1ebf b\u00e0o T\u00a0– m\u1ed9t lo\u1ea1i t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 t\u1eeb ng\u01b0\u1eddi b\u1ecb ung th\u01b0 v\u00e0 d\u00f9ng k\u1ef9 thu\u1eadt\u00a0ch\u1ec9nh s\u1eeda gen\u00a0gi\u00fap ch\u00fang c\u00f3 th\u1ec3 nh\u1eadn di\u1ec7n v\u00e0 t\u1ea5n c\u00f4ng t\u1ebf b\u00e0o b\u1ec7nh. \u0110\u01b0\u1ee3c th\u1eed nghi\u1ec7m l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 2013, ph\u01b0\u01a1ng ph\u00e1p n\u00e0y t\u1ecf ra hi\u1ec7u qu\u1ea3 khi c\u00f3 th\u1ec3 khi\u1ebfn cho t\u1ebf b\u00e0o ung th\u01b0 m\u00e1u c\u1ee7a c\u00e1c b\u1ec7nh nh\u00e2n bi\u1ebfn m\u1ea5t ch\u1ec9 trong v\u00f2ng 8 ng\u00e0y.<\/p>\n

\"\u0110ang<\/span><\/span>
\n\u1ea2nh minh h\u1ecda:\u00a0Animalsinscience<\/a><\/i>\u200b<\/div>\n

Tuy c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y hi\u1ec7n v\u1eabn ch\u01b0a ph\u1ed5 bi\u1ebfn v\u00e0 qu\u00e1 kh\u00f3 \u0111\u1ec3 \u00e1p d\u1ee5ng \u1edf nh\u1eefng kh\u1ed1i u r\u1eafn, nh\u00f3m c\u1ee7a Dotti \u0111\u00e3 c\u00f3 th\u1ec3 l\u00e0m ch\u1ee7 n\u00f3 \u0111\u1ed1i v\u1edbi vi\u1ec7c \u0111i\u1ec1u tr\u1ecb glioblastomas \u1edf chu\u1ed9t. Tr\u00ean kho\u1ea3ng 2\/3 b\u1ec1 m\u1eb7t c\u1ee7a kh\u1ed1i u glioblastomas, c\u00e1c chuy\u00ean gia t\u00ecm th\u1ea5y m\u1ed9t ph\u00e2n t\u1eed kh\u00e1c th\u01b0\u1eddng v\u1ed1n kh\u00f4ng c\u00f3 \u1edf c\u00e1c t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh. Ch\u00ednh v\u00ec v\u1eady, h\u1ecd \u0111\u00e3 tinh ch\u1ec9nh t\u1ebf b\u00e0o CAR-T cho ph\u00e9p ch\u00fang nh\u1eafm \u0111\u1ebfn \u0111\u1eb7c \u0111i\u1ec3m n\u00e0y, sau \u0111\u00f3 \u0111\u01b0a v\u00e0o c\u01a1 th\u1ec3 c\u1ee7a 10 con chu\u1ed9t \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1ea5y kh\u1ed1i u glioblastomas t\u1eeb ng\u01b0\u1eddi tr\u01b0\u1edbc \u0111\u00f3.<\/p>\n

K\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c cho th\u1ea5y kh\u1ed1i u \u0111\u00e3 bi\u1ebfn m\u1ea5t \u1edf 6 c\u00e1 th\u1ec3 chu\u1ed9t th\u1eed nghi\u1ec7m. \u1ede 4 con chu\u1ed9t c\u00f2n l\u1ea1i c\u0169ng nh\u01b0 m\u1ed9t nh\u00f3m 10 chu\u1ed9t kh\u00e1c kh\u00f4ng \u0111\u01b0\u1ee3c ti\u00eam t\u1ebf b\u00e0o T ch\u1ec9nh s\u1eeda, kh\u1ed1i u v\u1eabn ph\u00e1t tri\u1ec3n. Dotti cho bi\u1ebft \u00f4ng k\u1ef3 v\u1ecdng k\u1ef9 thu\u1eadt n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean c\u01a1 th\u1ec3 ng\u01b0\u1eddi v\u00e0o n\u0103m t\u1edbi v\u1edbi kho\u1ea3ng 19 b\u1ec7nh nh\u00e2n tham gia. N\u1ebfu thu \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 t\u01b0\u01a1ng t\u1ef1, \u0111\u00f3 s\u1ebd l\u00e0 b\u01b0\u1edbc ti\u1ebfn l\u1edbn trong vi\u1ec7c \u0111i\u00eau tr\u1ecb glioblastomas n\u00f3i ri\u00eang v\u00e0 ung th\u01b0 n\u00f3i chung.<\/p>\n

Ngu\u1ed3n:\u00a0Newscientist<\/a><\/i><\/b>\u200b<\/div>\n
tinhte.vn<\/div>\n","protected":false},"excerpt":{"rendered":"

Ung th\u01b0\u00a0l\u00e0 c\u0103n b\u1ec7nh v\u1ed1n \u0111\u00e3 kh\u00f3 trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb th\u00ec\u00a0ung th\u01b0 n\u00e3o\u00a0l\u1ea1i c\u00e0ng kh\u00f3 kh\u0103n h\u01a1n. Tuy nhi\u00ean, m\u1ed9t k\u1ef9 thu\u1eadt m\u1edbi \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u b\u1edfi c\u00e1c nh\u00e0 khoa h\u1ecdc th\u1eafp l\u00ean hy v\u1ecdng v\u1ec1 m\u1ed9t ng\u00e0y n\u00e0o \u0111\u00f3, ch\u00fang ta c\u00f3 th\u1ec3 l\u00e0m ch\u1ee7 v\u1ea5n \u0111\u1ec1 v\u00e0 ch\u1eefa l\u00e0nh c\u0103n b\u1ec7nh […]<\/p>\n","protected":false},"author":18,"featured_media":8766,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-8765","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8765","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=8765"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8765\/revisions"}],"predecessor-version":[{"id":8767,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8765\/revisions\/8767"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/8766"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=8765"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=8765"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=8765"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}