![\"52](\"http:\/\/khoahocvacongnghevietnam.com.vn\/images\/stories\/thang-2-2018\/52-cnghe.jpg\")
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C\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o \u0111\u01a1n IsoPlexis cho ph\u00e9p c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u m\u00f4 t\u1ea3 c\u00e1c t\u1ebf b\u00e0o d\u1ef1a tr\u00ean c\u00e1c protein m\u00e0 ch\u00fang ti\u1ebft ra (c\u00f3 t\u1edbi 42 cytokine, chemokine v\u00e0 c\u00e1c ph\u00e2n t\u1eed kh\u00e1c nhau). Cytokine l\u00e0 c\u00e1c protein hay glycoprotein kh\u00f4ng ph\u1ea3i kh\u00e1ng th\u1ec3 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t v\u00e0 ph\u00f3ng th\u00edch b\u1edfi c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u vi\u00eam v\u00e0 m\u1ed9t s\u1ed1 t\u1ebf b\u00e0o kh\u00e1c kh\u00f4ng ph\u1ea3i b\u1ea1ch c\u1ea7u.<\/p>\n
C\u00e1c protein n\u00e0y ho\u1ea1t \u0111\u1ed9ng trong vai tr\u00f2 l\u00e0 c\u00e1c ch\u1ea5t trung gian \u0111i\u1ec1u h\u00f2a gi\u1eefa c\u00e1c t\u1ebf b\u00e0o trong c\u01a1 th\u1ec3. Cytokine kh\u00e1c v\u1edbi c\u00e1c hormone kinh \u0111i\u1ec3n v\u00ec ch\u00fang \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi nhi\u1ec1u lo\u1ea1i t\u1ed5 ch\u1ee9c kh\u00e1c nhau ch\u1ee9 kh\u00f4ng ph\u1ea3i b\u1edfi c\u00e1c tuy\u1ebfn bi\u1ec7t h\u00f3a n\u00e0o. Cytokine l\u00e0 m\u1ed9t t\u1eadp h\u1ee3p r\u1ea5t nhi\u1ec1u c\u00e1c protein v\u00e0 peptit h\u00f2a tan c\u00f3 ch\u1ee9c n\u0103ng l\u00e0 nh\u1eefng y\u1ebfu t\u1ed1 \u0111i\u1ec1u h\u00f2a th\u1ec3 d\u1ecbch \u1edf n\u1ed3ng \u0111\u1ed9 r\u1ea5t th\u1ea5p (m\u1ee9c nanomole \u0111\u1ebfn picomole). Nh\u1eefng ph\u00e2n t\u1eed n\u00e0y \u0111i\u1ec1u h\u00f2a c\u00e1c ho\u1ea1t \u0111\u1ed9ng ch\u1ee9c n\u0103ng c\u1ee7a t\u1eebng t\u1ebf b\u00e0o ri\u00eang bi\u1ec7t v\u00e0 c\u1ee7a c\u1ea3 t\u1ed5 ch\u1ee9c trong tr\u01b0\u1eddng h\u1ee3p sinh l\u00fd v\u00e0 b\u1ec7nh l\u00fd. Nh\u1eefng protein n\u00e0y c\u0169ng l\u00e0m trung gian \u0111i\u1ec1u h\u00f2a tr\u1ef1c ti\u1ebfp s\u1ef1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa c\u00e1c t\u1ebf b\u00e0o v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c qu\u00e1 tr\u00ecnh x\u1ea3y ra trong khoang ngo\u1ea1i b\u00e0o. R\u1ea5t nhi\u1ec1u y\u1ebfu t\u1ed1 ph\u00e1t tri\u1ec3n v\u00e0 cytokine ho\u1ea1t \u0111\u1ed9ng nh\u01b0 nh\u1eefng y\u1ebfu t\u1ed1 gi\u00fap t\u1ebf b\u00e0o s\u1ed1ng s\u00f3t b\u1eb1ng c\u00e1ch ng\u0103n ng\u1eeba hi\u1ec7n t\u01b0\u1ee3ng ch\u1ebft t\u1ebf b\u00e0o theo l\u1eadp tr\u00ecnh.<\/p>\n
Kh\u1edfi \u0111\u1ea7u v\u00e0o th\u00e1ng 2\/2017 b\u1edfi Branford, IsoPlexis d\u1ef1a tr\u00ean Connecticut, v\u1edbi c\u00e1c chip IsoCode c\u00f3 h\u00e0ng ng\u00e0n khoang nh\u1ecf (microchamber) ch\u1ee9a c\u00e1c t\u1ebf b\u00e0o duy nh\u1ea5t. M\u1ed7i microchamber \u0111\u01b0\u1ee3c t\u00e1ch ra th\u00e0nh 15 ng\u0103n ch\u1ee9a 3 kh\u00e1ng th\u1ec3 kh\u00e1c nhau c\u1ee7a c\u00e1c protein c\u1ee5 th\u1ec3 \u0111\u01b0\u1ee3c g\u1eafn k\u1ebft ch\u1ea5t ch\u1ec9 th\u1ecb hu\u1ef3nh quang ba m\u00e0u, cho ph\u00e9p c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u00e2n bi\u1ec7t \u0111\u01b0\u1ee3c c\u00e1c protein m\u1ed9t c\u00e1ch d\u1ec5 d\u00e0ng.<\/p>\n
Gi\u00e1m \u0111\u1ed1c \u0111i\u1ec1u h\u00e0nh IsoPlexis – Sean Mackay cho bi\u1ebft, IsoPlexis c\u00f3 kh\u1ea3 n\u0103ng m\u00f4 t\u1ea3 h\u00e0ng ng\u00e0n t\u1ebf b\u00e0o T ho\u1eb7c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch m\u1ed9t l\u00fac, v\u1edbi 30 \u0111\u1ebfn 45 protein trong m\u1ed7i t\u1ebf b\u00e0o. \u0110\u00e2y l\u00e0 m\u1ed9t b\u01b0\u1edbc ti\u1ebfn th\u1ef1c s\u1ef1 trong l\u0129nh v\u1ef1c nghi\u00ean c\u1ee9u v\u1ec1 t\u1ebf b\u00e0o. C\u00e1c c\u00f4ng ngh\u1ec7 hi\u1ec7n t\u1ea1i ch\u1ec9 c\u00f3 th\u1ec3 \u0111o nhi\u1ec1u t\u1ebf b\u00e0o c\u00f9ng l\u00fac, l\u00e0m gi\u1ea3m s\u1ef1 chu\u1ea9n x\u00e1c, ho\u1eb7c ch\u1ec9 t\u1eadp trung v\u00e0o m\u1ed9t s\u1ed1 protein c\u1ee7a m\u1ed7i t\u1ebf b\u00e0o ri\u00eang l\u1ebb.<\/p>\n
(NASATI )<\/em><\/p>\n \n","protected":false},"excerpt":{"rendered":" C\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o \u0111\u01a1n IsoPlexis cho ph\u00e9p c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u m\u00f4 t\u1ea3 c\u00e1c t\u1ebf b\u00e0o d\u1ef1a tr\u00ean c\u00e1c protein m\u00e0 ch\u00fang ti\u1ebft ra (c\u00f3 t\u1edbi 42 cytokine, chemokine v\u00e0 c\u00e1c ph\u00e2n t\u1eed kh\u00e1c nhau). Cytokine l\u00e0 c\u00e1c protein hay glycoprotein kh\u00f4ng ph\u1ea3i kh\u00e1ng th\u1ec3 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t v\u00e0 ph\u00f3ng th\u00edch b\u1edfi c\u00e1c t\u1ebf […]<\/p>\n","protected":false},"author":18,"featured_media":8293,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-8292","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=8292"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8292\/revisions"}],"predecessor-version":[{"id":8591,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8292\/revisions\/8591"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/8293"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=8292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=8292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=8292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}