{"id":8166,"date":"2018-02-02T16:15:57","date_gmt":"2018-02-02T09:15:57","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=8166"},"modified":"2018-02-02T16:15:57","modified_gmt":"2018-02-02T09:15:57","slug":"cac-nha-khoa-hoc-da-tim-ra-phuong-phap-co-the-ngan-chan-di-ung-khong-xay-ra-nua","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/cac-nha-khoa-hoc-da-tim-ra-phuong-phap-co-the-ngan-chan-di-ung-khong-xay-ra-nua\/","title":{"rendered":"C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p c\u00f3 th\u1ec3 ng\u0103n ch\u1eb7n d\u1ecb \u1ee9ng kh\u00f4ng x\u1ea3y ra n\u1eefa"},"content":{"rendered":"

\u0110\u00e2y c\u00f3 l\u1ebd s\u1ebd l\u00e0 tin vui v\u1edbi r\u1ea5t nhi\u1ec1u ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng n\u1eb7ng v\u1edbi ph\u1ea5n hoa hay l\u00f4ng th\u00fa v\u1eadt.<\/p>\n

N\u1ebfu b\u1ea1n l\u00e0 m\u1ed9t trong s\u1ed1 nh\u1eefng ng\u01b0\u1eddi k\u00e9m may m\u1eafn b\u1ecb d\u1ecb \u1ee9ng v\u1edbi m\u1ed9t th\u1ee9 g\u00ec \u0111\u00f3, b\u1ea1n s\u1ebd c\u1ea3m th\u1ea5y c\u00f3 nh\u1eefng l\u00fac m\u00e0 thu\u1ed1c ch\u1eefa d\u1ecb \u1ee9ng c\u0169ng ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ebfn v\u1eady m\u00e0 th\u00f4i, ch\u1eb3ng th\u1ec3 n\u00e0o gi\u00fap b\u1ea1n tho\u00e1t kh\u1ecfi nh\u1eefng c\u01a1n ng\u1ee9a ng\u00e1y kh\u00f3 ch\u1ecbu m\u00e0 c\u01a1n d\u1ecb \u1ee9ng mang l\u1ea1i.<\/p>\n

Ch\u00ednh v\u00ec v\u1eady, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 t\u00edch c\u1ef1c t\u00ecm ki\u1ebfm nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ec3 c\u00f3 th\u1ec3 gi\u1ea3i quy\u1ebft tri\u1ec7t \u0111\u1ec3 c\u0103n b\u1ec7nh kh\u00f3 ch\u1ecbu n\u00e0y. V\u00e0 c\u00f3 v\u1ebb nh\u01b0 h\u1ecd \u0111\u00e3 t\u00ecm ra m\u1ed9t lo\u1ea1i kh\u00e1ng th\u1ec3 \u0111\u1eb7c bi\u1ec7t c\u00f3 kh\u1ea3 n\u0103ng ng\u0103n ch\u1eb7n ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng x\u1ea3y ra t\u1eeb s\u1edbm.<\/p>\n

Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng l\u00e0 c\u00e1ch m\u00e0 h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch ph\u1ea3n \u1ee9ng th\u00e1i qu\u00e1 \u0111\u1ed1i v\u1edbi m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng \u0111\u1ed1i l\u00e0nh t\u00ednh, ch\u1eb3ng h\u1ea1n nh\u01b0 protein trong c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m nh\u01b0 t\u00f4m, cua, hay l\u00f4ng v\u1eadt nu\u00f4i, v…v… Khi c\u01a1 th\u1ec3 ti\u1ebfp x\u00fac v\u1edbi ch\u1ea5t g\u00e2y d\u1ecb \u1ee9ng, h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch s\u1ebd s\u1ea3n sinh m\u1ed9t l\u01b0\u1ee3ng kh\u1ed5ng l\u1ed3 kh\u00e1ng th\u1ec3 mang t\u00ean immunoglobuline E (IgE). \u0110\u00f3 l\u00e0 m\u1ed9t ph\u00e2n t\u1eed l\u1edbn mang h\u00ecnh ch\u1eef Y, c\u00f3 kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u1edbi c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch mang nhi\u1ec7m v\u1ee5 t\u1ea5n c\u00f4ng c\u00e1c ch\u1ea5t h\u00f3a h\u1ecdc “l\u1ea1” x\u00e2m nh\u1eadp v\u00e0o c\u01a1 th\u1ec3. C\u00f9ng l\u00fac \u0111\u00f3, c\u01a1 th\u1ec3 ng\u01b0\u1eddi b\u1ec7nh s\u1ebd xu\u1ea5t hi\u1ec7n m\u1ed9t l\u01b0\u1ee3ng l\u1edbn histamine do h\u1ec7 mi\u1ec5n d\u1ecbch sinh ra, g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00f3 ch\u1ecbu c\u1ee7a d\u1ecb \u1ee9ng nh\u01b0 s\u1ed5 m\u0169i, ch\u1ea3y n\u01b0\u1edbc m\u1eaft, s\u01b0ng, ng\u1ee9a, n\u1ed5i m\u1ea9n v…v…<\/p>\n

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Th\u00f4ng th\u01b0\u1eddng, c\u00e1c thu\u1ed1c ch\u1eefa d\u1ecb \u1ee9ng s\u1ebd nh\u1eafm v\u00e0o c\u00e1c h\u1ee3p ch\u1ea5t g\u00e2y d\u1ecb \u1ee9ng trong h\u1ec7 mi\u1ec5n d\u1ecbch ho\u1eb7c th\u1ee5 th\u1ec3 c\u1ee7a ch\u00fang, t\u1eeb \u0111\u00f3 ng\u0103n ch\u1eb7n ho\u1eb7c gi\u1ea3m nh\u1eb9 c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00f3 ch\u1ecbu n\u00f3i tr\u00ean. Tuy nhi\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u tin r\u1eb1ng n\u1ebfu nh\u01b0 c\u00f3 m\u1ed9t lo\u1ea1i thu\u1ed1c n\u00e0o c\u00f3 c\u00f3 th\u1ec3 t\u1ea5n c\u00f4ng v\u00e0o IgE, c\u00f3 kh\u1ea3 n\u0103ng s\u1ebd khi\u1ebfn cho c\u00e1c ph\u1ea3n \u1ee9ng g\u00e2y d\u1ecb \u1ee9ng th\u1eadm ch\u00ed kh\u00f4ng x\u1ea3y ra trong c\u01a1 th\u1ec3.<\/p>\n

V\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc Aarhus, \u0110an M\u1ea1ch \u0111\u00e3 ph\u00e1t hi\u1ec7n ra m\u1ed9t c\u01a1 ch\u1ebf m\u1edbi s\u1eed d\u1ee5ng kh\u00e1ng th\u1ec3 kh\u00e1ng IgE, t\u1eeb \u0111\u00f3 gi\u00fap ch\u00fang ta gi\u1ea3i quy\u1ebft tri\u1ec7t \u0111\u1ec3 v\u1ea5n \u0111\u1ec1 d\u1ecb \u1ee9ng. Kh\u00e1ng th\u1ec3 n\u00f3i tr\u00ean mang t\u00ean 026 sdab, \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong l\u1ea1c \u0111\u00e0 kh\u00f4ng b\u01b0\u1edbu, v\u1edbi kh\u1ea3 n\u0103ng ng\u0103n ch\u1eb7n IgE \u0111\u1ebfn v\u1edbi hai lo\u1ea1i th\u1ee5 th\u1ec3 mi\u1ec5n d\u1ecbch l\u00e0 CD23 v\u00e0 FceRI – t\u1eeb \u0111\u00f3 khi\u1ebfn cho c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng kh\u00f4ng th\u1ec3 x\u1ea3y ra.<\/p>\n

M\u1eb7c d\u00f9 ph\u01b0\u01a1ng ph\u00e1p n\u00e0y ch\u01b0a \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi, tuy nhi\u00ean th\u1eed nghi\u1ec7m v\u1edbi m\u1eabu m\u00e1u c\u1ee7a nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh d\u1ecb \u1ee9ng cho th\u1ea5y 026 sdab gi\u00fap l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng IgE trong m\u00e1u xu\u1ed1ng h\u01a1n 30% ch\u1ec9 trong v\u00f2ng 15 ph\u00fat, v\u00e0 k\u1ebft qu\u1ea3 c\u00f2n kh\u1ea3 quan h\u01a1n n\u1eefa trong th\u1eddi gian d\u00e0i.<\/p>\n

“Gi\u1edd \u0111\u00e2y ch\u00fang t\u00f4i \u0111\u00e3 bi\u1ebft ch\u00ednh x\u00e1c c\u00e1ch m\u00e0 kh\u00e1ng th\u1ec3 n\u00e0y ng\u0103n ch\u1eb7n IgE li\u00ean k\u1ebft v\u1edbi th\u1ee5 th\u1ec3 mi\u1ec5n d\u1ecbch”\u00a0<\/i>– Nick Laursen, th\u00e0nh vi\u00ean c\u1ee7a nh\u00f3m nghi\u00ean c\u1ee9u, cho bi\u1ebft.\u00a0<\/i>“\u0110i\u1ec1u n\u00e0y cho ph\u00e9p ch\u00fang t\u00f4i ph\u00e1t tri\u1ec3n nh\u1eefng lo\u1ea1i thu\u1ed1c ch\u1eefa d\u1ecb \u1ee9ng ho\u00e0n to\u00e0n m\u1edbi trong t\u01b0\u01a1ng lai.”<\/i><\/p>\n

Tr\u00ean th\u1ecb tr\u01b0\u1eddng \u0111\u00e3 c\u00f3 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eefa d\u1ecb \u1ee9ng theo ph\u01b0\u01a1ng ph\u00e1p kh\u00e1ng IgE, mang t\u00ean omalizumab – v\u00e0 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i \u1edf 90 qu\u1ed1c gia tr\u00ean th\u1ebf gi\u1edbi. Tuy nhi\u00ean kh\u00f4ng ph\u1ea3i l\u00fac n\u00e0o lo\u1ea1i thu\u1ed1c n\u00e0y c\u0169ng \u0111\u1ea1t \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 nh\u01b0 mong \u0111\u1ee3i.<\/p>\n

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Theo nh\u01b0 nh\u00f3m nghi\u00ean c\u1ee9u, 026 sdab l\u00e0 m\u1ed9t lo\u1ea1i kh\u00e1ng th\u1ec3 c\u00f3 k\u00edch c\u1ee1 r\u1ea5t nh\u1ecf, \u0111\u1ed3ng th\u1eddi c\u0169ng r\u1ea5t d\u1ec5 s\u1ea3n xu\u1ea5t v\u00e0 lu\u00f4n lu\u00f4n \u1ed5n \u0111\u1ecbnh, t\u1eeb \u0111\u00f3 c\u00f3 th\u1ec3 s\u1ebd hi\u1ec7u qu\u1ea3 h\u01a1n h\u1eb3n so v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c ch\u1eefa d\u1ecb \u1ee9ng tr\u00ean th\u1ecb tr\u01b0\u1eddng.<\/p>\n

T\u1ea5t nhi\u00ean, v\u1eabn c\u00f2n ph\u1ea3i ch\u1edd m\u1ed9t th\u1eddi gian n\u1eefa cho \u0111\u1ebfn l\u00fac ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb tuy\u1ec7t v\u1eddi n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i cho c\u00e1c b\u1ec7nh nh\u00e2n d\u1ecb \u1ee9ng, do ch\u00fang ta v\u1eabn c\u00f2n ph\u1ea3i th\u1eed nghi\u1ec7m r\u1ea5t nhi\u1ec1u c\u0169ng nh\u01b0 nghi\u00ean c\u1ee9u v\u1ec1 t\u00ednh an to\u00e0n c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p m\u1edbi n\u00e0y.<\/p>\n

“Ch\u00fang t\u00f4i hy v\u1ecdng s\u1ebd c\u00f3 th\u1ec3 th\u00fac \u0111\u1ea9y s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ph\u00f2ng v\u00e0 ch\u1eefa d\u1ecb \u1ee9ng trong t\u01b0\u01a1ng lai” –\u00a0<\/i>nh\u00f3m nghi\u00ean c\u1ee9u cho bi\u1ebft.<\/p>\n

Nghi\u00ean c\u1ee9u n\u00e0y hi\u1ec7n \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u0103ng t\u1ea3i tr\u00ean t\u1ea1p ch\u00ed Nature Communications.<\/p>\n

Tham kh\u1ea3o Science Alert<\/i><\/p>\n

ngu\u1ed3n Genk<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u0110\u00e2y c\u00f3 l\u1ebd s\u1ebd l\u00e0 tin vui v\u1edbi r\u1ea5t nhi\u1ec1u ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng n\u1eb7ng v\u1edbi ph\u1ea5n hoa hay l\u00f4ng th\u00fa v\u1eadt. N\u1ebfu b\u1ea1n l\u00e0 m\u1ed9t trong s\u1ed1 nh\u1eefng ng\u01b0\u1eddi k\u00e9m may m\u1eafn b\u1ecb d\u1ecb \u1ee9ng v\u1edbi m\u1ed9t th\u1ee9 g\u00ec \u0111\u00f3, b\u1ea1n s\u1ebd c\u1ea3m th\u1ea5y c\u00f3 nh\u1eefng l\u00fac m\u00e0 thu\u1ed1c […]<\/p>\n","protected":false},"author":18,"featured_media":8167,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-8166","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=8166"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8166\/revisions"}],"predecessor-version":[{"id":8168,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8166\/revisions\/8168"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/8167"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=8166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=8166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=8166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}