{"id":8029,"date":"2018-02-02T16:13:51","date_gmt":"2018-02-02T09:13:51","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=8029"},"modified":"2018-02-02T16:13:51","modified_gmt":"2018-02-02T09:13:51","slug":"ban-co-biet-tai-sao-chi-moi-co-1-nguoi-duoc-chua-khoi-hiv","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/ban-co-biet-tai-sao-chi-moi-co-1-nguoi-duoc-chua-khoi-hiv\/","title":{"rendered":"[B\u1ea1n c\u00f3 bi\u1ebft] T\u1ea1i sao ch\u1ec9 m\u1edbi c\u00f3 1 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi HIV?"},"content":{"rendered":"

H\u1ed3i n\u0103m 2007, Timothy Ray Brown – m\u1ed9t ng\u01b0\u1eddi \u0111\u00e0n \u00f4ng tr\u1ebb ng\u01b0\u1eddi M\u1ef9 s\u1ed1ng \u1edf Berlin \u0111\u00e3 tr\u1edf th\u00e0nh k\u1ef3 t\u00edch trong ng\u00e0nh y h\u1ecdc hi\u1ec7n \u0111\u1ea1i khi \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa l\u00e0nh\u00a0HIV\u00a0sau 12 n\u0103m chung s\u1ed1ng v\u1edbi c\u0103n b\u1ec7nh th\u1ebf k\u1ef7 n\u00e0y. Khi \u0111\u00f3, k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh virus HIV \u0111\u00e3 b\u1ea5t ng\u1edd bi\u1ebfn m\u1ea5t kh\u1ecfi c\u01a1 th\u1ec3 \u00f4ng. Brown tr\u01b0\u1edbc \u0111\u00f3 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n l\u00e0 \u0111ang m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u v\u00e0 \u0111\u01b0\u1ee3c c\u1ea5y gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb. V\u00e0 h\u00f3a ra ng\u01b0\u1eddi hi\u1ebfn t\u1ebf b\u00e0o g\u1ed1c l\u1ea1i s\u1edf h\u1eefu m\u1ed9t d\u1ea1ng \u0111\u1ed9t bi\u1ebfn g\u1ecdi l\u00e0 CCR5-delta 32, gi\u00fap Brown c\u00f3 th\u1ec3 ch\u1ed1ng l\u1ea1i HIV. K\u1ec3 t\u1eeb \u0111\u00f3, ng\u01b0\u1eddi ta g\u1ecdi Brown l\u00e0 \u201cb\u1ec7nh nh\u00e2n Berlin\u201d v\u00e0 \u0111\u1ebfn gi\u1edd, \u0111\u00e2y v\u1eabn l\u00e0 tr\u01b0\u1eddng h\u1ee3p duy nh\u1ea5t t\u1eebng \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi HIV ho\u00e0n to\u00e0n. T\u1ea1i sao v\u1eady?<\/p>\n

M\u1eb7c d\u00f9 \u0111\u00e3 c\u00f3 r\u1ea5t nhi\u1ec1u ti\u1ebfn b\u1ed9 trong l\u0129nh v\u1ef1c\u00a0khoa h\u1ecdc\u00a0k\u1ef9 thu\u1eadt, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong gi\u1edbi y sinh, nh\u01b0ng k\u1ef3 th\u1ef1c m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa tr\u1ecb tri\u1ec7t \u0111\u1ec3 HIV v\u1eabn l\u00e0 \u1ea9n s\u1ed1. Hi\u1ec7n c\u00e1c gi\u1ea3i ph\u00e1p kh\u00e1ng virus (ART) v\u1ec1 c\u01a1 b\u1ea3n ch\u1ec9 l\u00e0 chuy\u1ec3n HIV t\u1eeb m\u1ed9t b\u1ea3n \u00e1n t\u1eed h\u00ecnh th\u00e0nh d\u1ea1ng h\u1ed9i ch\u1ee9ng c\u00f3 th\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c ch\u1ee9 v\u1eabn ch\u01b0a th\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u1eadn g\u1ed1c. B\u1edfi l\u1ebd HIV \u0111\u00e3 v\u0129nh vi\u1ec5n \u201ct\u00edch h\u1ee3p\u201d v\u00e0o trong b\u1ed9 gen c\u1ee7a nh\u1eefng t\u1ebf b\u00e0o nhi\u1ec5m b\u1ec7nh, sau \u0111\u00f3 \u1ea9n n\u1ea5p, ng\u1ee7 \u0111\u00f4ng trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi, khi\u1ebfn cho vi\u1ec7c \u201cb\u1ee9ng\u201d n\u00f3 ra kh\u1ecfi c\u01a1 th\u1ec3 l\u00e0 g\u1ea7n nh\u01b0 b\u1ea5t kh\u1ea3 thi. T\u1eeb nh\u1eefng n\u0103m 1980, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u hy v\u1ecdng r\u1eb1ng c\u00f3 th\u1ec3 d\u00f9ng li\u1ec7u ph\u00e1p gen, c\u1ee5 th\u1ec3 l\u00e0 s\u1eed d\u1ee5ng v\u1eadt li\u1ec7u di truy\u1ec1n \u0111\u00e3 tinh ch\u1ec9nh c\u1ee7a c\u01a1 th\u1ec3 ng\u01b0\u1eddi, \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c th\u1eadm ch\u00ed l\u00e0\u00a0ch\u1eefa HIV. Tr\u01b0\u1eddng h\u1ee3p c\u1ee7a Brown \u0111\u00e3 kh\u01a1i d\u1eady tia hy v\u1ecdng cho nhi\u1ec1u nh\u00e0 nghi\u00ean c\u1ee9u nh\u01b0ng cu\u1ed1i c\u00f9ng, h\u1ecd v\u1eabn \u0111ang quanh qu\u1ea9n v\u1edbi c\u00e1ch ti\u1ebfp c\u1eadn \u0111\u00f3.<\/p>\n

\"\u0110ang<\/span><\/span>
\nBrown – ng\u01b0\u1eddi \u0111\u1ea7u ti\u00ean v\u00e0 duy nh\u1ea5t t\u00ednh t\u1edbi hi\u1ec7n t\u1ea1i \u0111\u01b0\u1ee3c ch\u1eefa ho\u00e0n to\u00e0n kh\u1ecfi HIV<\/i>\u200b<\/div>\n

M\u1ed9t nghi\u00ean c\u1ee9u c\u00f4ng b\u1ed1 c\u00e1ch \u0111\u00e2y v\u00e0i th\u00e1ng tr\u00ean PLOS Pathogens \u0111\u00e3 ch\u1ec9 ra m\u1ed9t h\u01b0\u1edbng m\u1edbi trong vi\u1ec7c ch\u1eefa HIV, \u0111\u1ed3ng th\u1eddi ch\u1ec9 ra nh\u1eefng kh\u00f3 kh\u0103n c\u00f9ng c\u1ef1c m\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111ang ph\u1ea3i \u0111\u1ed1i m\u1eb7t. C\u1ee5 th\u1ec3, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 l\u1ea5y \u00fd t\u01b0\u1edfng t\u1eeb tr\u01b0\u1eddng h\u1ee3p c\u1ee7a Brown, t\u1eeb \u0111\u00f3 t\u00ecm c\u00e1ch tinh ch\u1ec9nh t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ec3 k\u00edch th\u00edch h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 nh\u1eb1m ti\u00eau di\u1ec7t HIV. \u0110\u1ea7u ti\u00ean, c\u00e1c t\u1ebf b\u00e0o g\u1ed1c t\u1ea1o m\u00e1u s\u1ebd \u0111\u01b0\u1ee3c tinh ch\u1ec9nh \u0111\u1ec3 mang gen bi\u1ebfn n\u00f3 tr\u1edf th\u00e0nh nh\u1eefng \u201cs\u00e1t th\u1ee7\u201d nh\u1eafm m\u1ee5c ti\u00eau t\u1edbi HIV. C\u00e1c t\u1ebf b\u00e0o n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng ph\u00e1t hi\u1ec7n v\u00e0 ph\u00e1 h\u1ee7y nh\u1eefng t\u1ebf b\u00e0o \u0111\u00e3 b\u1ecb nhi\u1ebdm HIV khi ch\u00fang xu\u1ea5t hi\u1ec7n trong c\u01a1 th\u1ec3. B\u1ea3n ch\u1ea5t c\u1ee7a k\u1ef9 thu\u1eadt n\u00e0y l\u00e0 t\u01b0\u1edbc \u0111i ph\u1ea7n t\u1eed CD4 v\u1ed1n \u0111\u01b0\u1ee3c HIV l\u1ee3i d\u1ee5ng \u0111\u1ec3 li\u00ean k\u1ebft v\u1edbi b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o, coi \u0111\u00e2y nh\u01b0 m\u1ed9t d\u1ea5u hi\u1ec7u g\u1eafn v\u1edbi HIV v\u00e0 ti\u00eau di\u1ec7t n\u00f3. Trong th\u1eed nghi\u1ec7m, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 \u0111\u01b0a nh\u1eefng t\u1ebf b\u00e0o g\u1ed1c n\u00e0y v\u00e0o c\u01a1 th\u1ec3 c\u1ee7a 2 con linh tr\u01b0\u1edfng th\u00f4ng qua ph\u1eabu thu\u1eadt gh\u00e9p t\u1ee7y. To\u00e0n b\u1ed9 qu\u00e1 tr\u00ecnh n\u00e0y h\u00ecnh th\u00e0nh n\u00ean m\u1ed9t bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb g\u1ecdi l\u00e0 li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch CAR-T.<\/p>\n

CAR-T tr\u01b0\u1edbc \u0111\u00e2y \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 m\u1ed9t trong nh\u1eefng c\u00e1ch \u0111\u1ec3 ch\u1eefa HIV hi\u1ec7u qu\u1ea3 nh\u01b0ng v\u1edbi c\u00e1ch ti\u1ebfp c\u1eadn m\u1edbi n\u00e0y, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u00f2n ph\u00e1t hi\u1ec7n r\u1eb1ng c\u01a1 th\u1ec3 c\u1ee7a lo\u00e0i linh tr\u01b0\u1edfng c\u00f3 kh\u1ea3 n\u0103ng duy tr\u00ec qu\u00e1 tr\u00ecnh s\u1ea3n sinh ra t\u1ebf b\u00e0o CAR trong v\u00f2ng h\u01a1n 2 n\u0103m k\u1ec3 t\u1eeb th\u1eddi \u0111i\u1ec3m c\u1ea5y v\u00e0o c\u01a1 th\u1ec3 m\u00e0 kh\u00f4ng g\u00e2y ra b\u1ea5t c\u1ee9 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o. \u0110i\u1ec1u n\u00e0y cho th\u1ea5y c\u00e1ch l\u00e0m n\u00e0y c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t gi\u1ea3i ph\u00e1p d\u00e0i h\u1ea1n nh\u1eb1m gi\u1ea3m s\u1ef1 ph\u1ee5 thu\u1ed9c c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0o li\u1ec7u ph\u00e1p kh\u00e1ng virus v\u00e0 th\u1eadm ch\u00ed l\u00e0 c\u00f3 th\u1ec3 qu\u00e9t s\u1ea1ch HIV ra kh\u1ecfi c\u01a1 th\u1ec3, t\u1ea5n c\u00f4ng v\u00e0o c\u1ea3 nh\u1eefng con HIV \u0111ang \u1ea9n n\u00e1o s\u00e2u trong c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n ngay khi ch\u00fang b\u1eaft \u0111\u1ea7u t\u00e1i t\u1ea5n c\u00f4ng.<\/p>\n

\"\u0110ang<\/span><\/span>\u200b<\/div>\n

Scott Kitchen, ng\u01b0\u1eddi d\u1eabn \u0111\u1ea7u nghi\u00ean c\u1ee9u cho bi\u1ebft: \u201cCh\u00fang ta ch\u1ec9 m\u1edbi c\u00f3 m\u1ed9t b\u1ec7nh nh\u00e2n duy nh\u1ea5t \u0111\u01b0\u1ee3c ch\u1eefa tr\u1ecb hi\u1ec7u qu\u1ea3. Tuy nhi\u00ean \u0111i\u1ec1u \u0111\u00f3 l\u00e0 r\u1ea5t \u0111\u00e1ng kh\u00edch l\u1ec7. HIV \u0111\u00e3 l\u00e0m t\u1ed5n th\u01b0\u01a1ng ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch c\u1ee7a t\u1ebf b\u00e0o v\u00e0 \u0111\u00e2y ch\u00ednh l\u00e0 \u0111i\u1ec3m m\u1ea1nh c\u1ee7a n\u00f3. V\u00ec v\u1eady, \u0111\u1ec3 c\u00f3 th\u1ec3 qu\u00e9t s\u1ea1ch n\u00f3 ra kh\u1ecfi c\u01a1 th\u1ec3 th\u00ec ch\u00fang ta c\u1ea7n m\u1ed9t ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch hi\u1ec7u qu\u1ea3. Ch\u00fang t\u00f4i \u0111ang t\u00ecm c\u00e1ch th\u1ef1c hi\u1ec7n \u0111i\u1ec1u \u0111\u00f3. V\u00e0 ch\u00fang t\u00f4i tin r\u1eb1ng \u0111\u00e2y l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a vi\u1ec7c ch\u1eefa tr\u1ecb, c\u00f3 th\u1ec3 k\u1ebft h\u1ee3p v\u1edbi nh\u1eefng th\u1ee9 kh\u00e1c nh\u01b0 li\u1ec7u ph\u00e1p kh\u00e1ng virus \u0111\u1ec3 h\u00ecnh th\u00e0nh n\u00ean m\u1ed9t bi\u1ec7n ph\u00e1p ch\u1eefa tr\u1ecb hi\u1ec7u qu\u1ea3.\u201d<\/p>\n

G\u1ea7n \u0111\u00e2y, m\u1ed9t s\u1ed1 \u0111\u1ed9t ph\u00e1 kh\u00e1c trong vi\u1ec7c ti\u00eau di\u1ec7t ho\u00e0n to\u00e0n HIV \u0111\u00e3 \u0111\u01b0\u1ee3c c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u00f4ng b\u1ed1 nh\u01b0ng h\u1ecd v\u1eabn ch\u1ee7 y\u1ebfu ch\u1ec9 m\u1edbi ch\u1eefa th\u00e0nh c\u00f4ng tr\u00ean chu\u1ed9t. H\u1ed3i \u0111\u1ea7u n\u0103m ngo\u00e1i, nh\u00f3m c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc Temple \u0111\u00e3 d\u00f9ng b\u1ed9 c\u00f4ng c\u1ee5 ch\u1ec9nh s\u1eeda gen CRISPR \u0111\u1ec3 ch\u1ec9nh s\u1eeda DNA c\u1ee7a HIV trong c\u01a1 th\u1ec3 chu\u1ed9t. M\u1ed9t s\u1ed1 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng kh\u00e1c c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh nh\u1eb1m ch\u1eefa HIV tr\u00ean c\u01a1 th\u1ec3 ng\u01b0\u1eddi b\u1eb1ng c\u00e1ch k\u1ebft h\u1ee3p li\u1ec7u ph\u00e1p gen v\u1edbi t\u1ebf b\u00e0o g\u1ed1c, tuy nhi\u00ean hi\u1ec7n v\u1eabn ch\u01b0a r\u00f5 r\u1eb1ng bi\u1ec7n ph\u00e1p n\u00e0y c\u00f3 th\u1eadt s\u1ef1 k\u00e9o d\u00e0i hay kh\u00f4ng. Th\u1eadm ch\u00ed, h\u1ed3i \u0111\u1ea7u n\u0103m ngo\u00e1i, m\u1ed9t “biohacker” c\u00f2n t\u1ef1 ti\u00eam li\u1ec7u ph\u00e1p ch\u1eefa HIV v\u00e0o c\u01a1 th\u1ec3 nh\u01b0ng r\u00f5 r\u00e0ng, kh\u1ea3 n\u0103ng th\u00e0nh c\u00f4ng l\u00e0 kh\u00f4ng th\u1ec3 l\u01b0\u1eddng tr\u01b0\u1edbc \u0111\u01b0\u1ee3c.<\/p>\n

\"\u0110ang<\/span><\/span>
\nNg\u01b0\u1eddi t\u1ef1 ti\u00eam li\u1ec7u ph\u00e1p ch\u1eefa HIV v\u00e0o c\u01a1 th\u1ec3 \u0111\u1ec3 th\u1eed nghi\u1ec7m<\/i>\u200b<\/div>\n

Nh\u1eefng c\u00f4ng ngh\u1ec7 nh\u01b0 tinh ch\u1ec9nh gen nh\u1eb1m t\u00ecm ki\u1ebfm c\u00e1ch ch\u1eefa l\u00e0nh HIV nghe c\u00f3 v\u1ebb kh\u1ea3 thi nh\u01b0ng v\u1eabn c\u00f2n r\u1ea5t nhi\u1ec1u tr\u1edf ng\u1ea1i v\u1ec1 m\u1eb7t k\u1ef9 thu\u1eadt. B\u1edfi th\u1ebf, v\u1eabn c\u00f2n m\u1ed9t ch\u1eb7ng \u0111\u01b0\u1eddng d\u00e0i v\u00e0 cam go ph\u00eda tr\u01b0\u1edbc \u0111\u1ec3 lo\u00e0i ng\u01b0\u1eddi ch\u1ea1m t\u1edbi \u0111\u01b0\u1ee3c bi\u1ec7n ph\u00e1p ch\u1eefa tr\u1ecb HIV hi\u1ec7u qu\u1ea3. R\u00e0o c\u1ea3n l\u1edbn nh\u1ea5t trong vi\u1ec7c ph\u00e1t tri\u1ec3n bi\u1ec7n ph\u00e1p ch\u1eefa tr\u1ecb ch\u00ednh l\u00e0 n\u00f3 ph\u1ea3i c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ee7 l\u00e2u d\u00e0i \u0111\u1ec3 chi\u1ebfn \u0111\u1ea5u v\u1edbi l\u01b0\u1ee3ng virus \u0111\u00f4ng \u0111\u1ea3o v\u00e0 dai d\u1eb3n \u1ea9n trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi. \u0110\u00e2y l\u00e0 v\u1ea5n \u0111\u1ec1 m\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i UCLA \u0111ang t\u00ecm c\u00e1ch gi\u1ea3i quy\u1ebft. Nh\u01b0ng \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c \u0111i\u1ec1u \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc ph\u1ea3i c\u1ea3i thi\u1ec7n \u0111\u01b0\u1ee3c k\u1ef9 thu\u1eadt tinh ch\u1ec9nh t\u1ebf b\u00e0o trong c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n thay v\u00ec ph\u1ea3i l\u1ea5y ch\u00fang ra ngo\u00e0i, tinh ch\u1ec9nh trong ph\u00f2ng th\u00ed nghi\u1ec7m v\u00e0 sau \u0111\u00f3 l\u1ea1i \u0111\u01b0a tr\u1edf l\u1ea1i c\u01a1 th\u1ec3. M\u1eb7t kh\u00e1c, ng\u01b0\u1eddi ta c\u00f2n ph\u1ea3i n\u00e2ng c\u1ea5p kh\u1ea3 n\u0103ng \u0111\u1ecbnh v\u1ecb c\u00e1c gen c\u1ea7n ch\u1ec9nh s\u1eeda v\u1ed1n r\u1ea3i r\u00e1c kh\u1eafp c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n. Ph\u1ee9c t\u1ea1p h\u01a1n n\u1eefa, do HIV c\u00f3 kh\u1ea3 n\u0103ng \u201cti\u1ebfn h\u00f3a\u201d \u0111\u1ec3 ch\u1ed1ng l\u1ea1i c\u00e1c ph\u00e9p \u0111i\u1ec1u tr\u1ecb n\u00ean ngay c\u1ea3 CRISPR c\u0169ng ph\u1ea3i c\u1ea7n ph\u1ea3i k\u1ebft h\u1ee3p t\u1edbi nhi\u1ec1u bi\u1ec7n ph\u00e1p kh\u00e1c nh\u1eb1m n\u00e2ng cao kh\u1ea3 n\u0103ng th\u00e0nh c\u00f4ng.<\/p>\n

G\u1ea7n \u0111\u00e2y, Qu\u1ef9 \u0111\u1ea7u t\u01b0 nghi\u00ean c\u1ee9u\u00a0AIDS\u00a0\u0111\u00e3 \u0111\u01b0a ra y\u00eau c\u1ea7u c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u1ea3i t\u00ecm c\u00e1ch kh\u1eafc ph\u1ee5c nh\u1eefng r\u00e0o c\u1ea3n \u0111\u00f3. Rowena Johnson, gi\u00e1m \u0111\u1ed1c nghi\u00ean c\u1ee9u c\u1ee7a t\u1ed5 ch\u1ee9c n\u00e0y cho bi\u1ebft: \u201cS\u1ef1 t\u1ed3n t\u1ea1i c\u1ee7a nh\u1eefng c\u00f4ng c\u1ee5 v\u00e0 m\u1ee5c ti\u00eau hi\u1ec7n t\u1ea1i cho th\u1ea5y r\u1eb1ng vi\u1ec7c thi\u1ebft k\u1ebf n\u00ean m\u1ed9t li\u1ec7u ph\u00e1p gen nh\u1eb1m ch\u1eefa tr\u1ecb HIV \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 v\u1ea5n \u0111\u1ec1 c\u00f4ng ngh\u1ec7 ch\u1ee9 kh\u00f4ng ph\u1ea3i l\u00e0 \u0111i kh\u00e1m ph\u00e1. Tuy nhi\u00ean, t\u00ednh kh\u1ea3 thi c\u1ee7a c\u00e1c c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y v\u1eabn l\u00e0 m\u1ed9t tr\u1edf ng\u1ea1i l\u1edbn. Th\u1eddi gian, chi ph\u00ed v\u00e0 s\u1ef1 ph\u1ee9c t\u1ea1p c\u1ee7a vi\u1ec7c th\u1eed nghi\u1ec7m li\u1ec7u ph\u00e1p gen trong l\u00e2m s\u00e0ng l\u00e0 nh\u1eefng minh ch\u1ee9ng r\u00f5 r\u00e0ng nh\u1ea5t.\u201d<\/p>\n

\"\u0110ang<\/span><\/span>\u00a0\u200b<\/div>\n

Cho \u0111\u1ebfn nay, ng\u01b0\u1eddi ta ng\u00e0y c\u00e0ng hy v\u1ecdng c\u00f3 th\u1ec3 d\u00f9ng li\u1ec7u ph\u00e1p gen \u0111\u1ec3 khi\u1ebfn h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a t\u1ebf b\u00e0o c\u01a1 th\u1ec3 t\u1ef1 ch\u1ed1ng l\u1ea1i HIV. \u0110\u1ed1i v\u1edbi c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y, virus \u0111\u00e3 b\u1ecb ng\u0103n ch\u1eb7n x\u00e2m nh\u1eadp t\u1ea1i th\u1eddi \u0111i\u1ec3m ban \u0111\u1ea7u. Vi\u1ec7c l\u00e0m n\u00e0y t\u01b0\u01a1ng \u0111\u1ed1i \u0111\u01a1n gi\u1ea3n b\u1edfi kh\u00f4ng c\u1ea7n ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi vi\u1ec7c ng\u0103n ch\u1eb7n l\u01b0\u1ee3ng virus \u0111ang \u201cng\u1ee7 \u0111\u00f4ng\u201d tr\u1ed5i d\u1eady sau th\u1eddi gian d\u00e0i v\u00e0 hi\u1ec7n \u0111\u00e3 c\u00f3 m\u1ed9t s\u1ed1 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh.<\/p>\n

Cu\u1ed1i c\u00f9ng, Kitchen kh\u1eb3ng \u0111\u1ecbnh r\u1eb1ng: \u201cBrown l\u00e0 m\u1ed9t tr\u01b0\u1eddng h\u1ee3p phi th\u01b0\u1eddng. Anh ta \u0111\u00e3 tr\u1ea3i qua 2 l\u1ea7n c\u1ea5y gh\u00e9p t\u1ee7y – \u0111i\u1ec1u m\u00e0 th\u01b0\u1eddng ng\u01b0\u1eddi ta kh\u00f4ng th\u1ec3 s\u1ed1ng s\u00f3t qua \u0111\u01b0\u1ee3c. V\u00e0 ch\u00fang ta k\u1ef3 th\u1ef1c v\u1eabn kh\u00f4ng bi\u1ebft ch\u00ednh x\u00e1c n\u00f3 ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o.\u201d<\/p>\n

Trong nghi\u00ean c\u1ee9u c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i UCLA, r\u00e0o c\u1ea3n l\u1edbn nh\u1ea5t ch\u00ednh l\u00e0 t\u00ecm ra \u0111\u01b0\u1ee3c c\u00e1ch hi\u1ec7u qu\u1ea3 nh\u1ea5t \u0111\u1ec3 c\u1ea5y gh\u00e9p l\u01b0\u1ee3ng t\u1ebf b\u00e0o g\u1ed1c nh\u1ecf nh\u1ea5t v\u00e0o c\u01a1 th\u1ec3 c\u1ee7a m\u1ed9t b\u1ec7nh nh\u00e2n HIV. L\u00fd t\u01b0\u1edfng nh\u1ea5t, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho bi\u1ebft r\u1eb1ng h\u1ecd mu\u1ed1n t\u1ea1o ra m\u1ed9t th\u1ee9 nh\u01b0 vaccine m\u00e0 kh\u00f4ng c\u1ea7n ph\u1ea3i ti\u1ebfn h\u00e0nh c\u00e1c th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n nh\u01b0 gh\u00e9p t\u1ee7y. Tuy nhi\u00ean, hi\u1ec7n t\u1ea1i th\u00ec suy ngh\u0129 n\u00e0y v\u1eabn c\u00f2n \u0111\u01b0\u1ee3c x\u1ebfp v\u00e0o h\u00e0ng \u201ckhoa h\u1ecdc vi\u1ec5n t\u01b0\u1edfng.\u201d Kitchen cho bi\u1ebft \u1edf hi\u1ec7n t\u1ea1i, c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng d\u1ef1a theo c\u00e1c c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y c\u00f3 th\u1ec3 ch\u1ec9 m\u1ea5t kho\u1ea3ng 2 – 3 n\u0103m n\u1eefa. B\u1edfi th\u1ebf, c\u00f3 th\u1ec3 c\u00e1ch ch\u1eefa tr\u1ecb v\u1eabn ch\u01b0a c\u00f3 \u1edf hi\u1ec7n t\u1ea1i nh\u01b0ng \u00edt nh\u1ea5t, hy v\u1ecdng \u0111ang ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c hun \u0111\u00fac l\u1edbn h\u01a1n. Hy v\u1ecdng r\u1eb1ng c\u00e1c nh\u00e0 khoa h\u1ecdc s\u1ebd s\u1edbm t\u00ecm \u0111\u01b0\u1ee3c c\u00e1ch hi\u1ec7u qu\u1ea3 qu\u00e9t s\u1ea1ch HIV ra kh\u1ecfi c\u01a1 th\u1ec3 ng\u01b0\u1eddi nh\u01b0 c\u00e1ch m\u00e0 h\u1ecd \u0111\u00e3 t\u1eebng l\u00e0m v\u1edbi nhi\u1ec1u c\u0103n b\u1ec7nh ch\u1ebft ng\u01b0\u1eddi kh\u00e1c trong l\u1ecbch s\u1eed. Khi \u0111\u00f3, m\u1ed9t b\u1ea3n \u00e1n t\u1eed h\u00ecnh s\u1ebd \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf.<\/p>\n

Tham kh\u1ea3o Gizmodo (1<\/a>) (2<\/a>),\u00a0SM<\/a>,\u00a0SD<\/a>,\u00a0CBS<\/a>,\u00a0BW<\/a>,\u00a0Nature<\/a>,\u00a0NCBI<\/a>,\u00a0Amfar<\/a><\/i><\/b>\u200b<\/div>\n
Ngu\u1ed3n Tinhte.vn<\/div>\n","protected":false},"excerpt":{"rendered":"

H\u1ed3i n\u0103m 2007, Timothy Ray Brown – m\u1ed9t ng\u01b0\u1eddi \u0111\u00e0n \u00f4ng tr\u1ebb ng\u01b0\u1eddi M\u1ef9 s\u1ed1ng \u1edf Berlin \u0111\u00e3 tr\u1edf th\u00e0nh k\u1ef3 t\u00edch trong ng\u00e0nh y h\u1ecdc hi\u1ec7n \u0111\u1ea1i khi \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa l\u00e0nh\u00a0HIV\u00a0sau 12 n\u0103m chung s\u1ed1ng v\u1edbi c\u0103n b\u1ec7nh th\u1ebf k\u1ef7 n\u00e0y. Khi \u0111\u00f3, k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh virus HIV \u0111\u00e3 […]<\/p>\n","protected":false},"author":18,"featured_media":8030,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-8029","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=8029"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8029\/revisions"}],"predecessor-version":[{"id":8031,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/8029\/revisions\/8031"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/8030"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=8029"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=8029"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=8029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}