{"id":6105,"date":"2017-08-17T19:34:11","date_gmt":"2017-08-17T12:34:11","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=6105"},"modified":"2017-10-03T09:29:33","modified_gmt":"2017-10-03T02:29:33","slug":"tim-ra-phuong-phap-su-dung-khang-sinh-chinh-xac-va-it-gay-hai-cho-co-the-hon-nhieu","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/tim-ra-phuong-phap-su-dung-khang-sinh-chinh-xac-va-it-gay-hai-cho-co-the-hon-nhieu\/","title":{"rendered":"T\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng kh\u00e1ng sinh ch\u00ednh x\u00e1c v\u00e0 \u00edt g\u00e2y h\u1ea1i cho c\u01a1 th\u1ec3 h\u01a1n nhi\u1ec1u"},"content":{"rendered":"

Nh\u1eefng c\u1ed7 xe t\u00ed hon v\u1eadn chuy\u1ec3n kh\u00e1ng sinh an to\u00e0n qua m\u00f4i tr\u01b0\u1eddng axit d\u1ea1 d\u00e0y<\/strong><\/p>\n

\"\"<\/p>\n

M\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 ph\u00e1 h\u1ee7y t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c kh\u00e1ng sinh, kh\u00f4ng ph\u1ea3i si\u00eau vi khu\u1ea9n, m\u00e0 l\u00e0 ch\u00ednh axit trong d\u1ea1 d\u00e0y. C\u00e1c lo\u1ea1i thu\u1ed1c nh\u1ea1y c\u1ea3m v\u1edbi axit \u0111\u00f4i khi tr\u1edf n\u00ean kh\u00f4ng hi\u1ec7u qu\u1ea3 khi n\u00f3 t\u1edbi \u0111\u01b0\u1ee3c ru\u1ed9t \u0111\u1ec3 h\u1ea5p th\u1ee5.
\nB\u00e2y gi\u1edd, c\u00e1c chuy\u00ean gia c\u00f4ng ngh\u1ec7 nano t\u1ea1i \u0110\u1ea1i h\u1ecdc California San Diego \u0111\u00e3 t\u00ecm ra m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ec3 b\u1ea3o v\u1ec7 thu\u1ed1c \u0111i qua m\u00f4i tr\u01b0\u1eddng d\u1ea1 d\u00e0y. H\u1ecd t\u1ea1o ra nh\u1eefng c\u1ea5u tr\u00fac \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 \u201cmicromotors\u201d l\u00e0m t\u1eeb magie, titan oxyt v\u00e0 chitosan, m\u1ed9t lo\u1ea1i polyme c\u00f3 ngu\u1ed3n g\u1ed1c trong v\u1ecf \u0111\u1ed9ng v\u1eadt gi\u00e1p x\u00e1c.<\/p>\n

C\u00f3 th\u1ec3 hi\u1ec3u micromotors gi\u1ed1ng nh\u01b0 nh\u1eefng chi\u1ebfc xe t\u00ed hon, \u0111i v\u00e0o c\u01a1 th\u1ec3 \u0111\u1ec3 v\u1eadn chuy\u1ec3n thu\u1ed1c tr\u1ef1c ti\u1ebfp \u0111\u1ebfn v\u1ecb tr\u00ed nhi\u1ec5m khu\u1ea9n. N\u00f3 s\u1ebd t\u0103ng hi\u1ec7u qu\u1ea3 c\u1ee7a kh\u00e1ng sinh, trong b\u1ed1i c\u1ea3nh vi khu\u1ea9n ng\u00e0y c\u00e0ng tr\u1edf n\u00ean kh\u00e1ng thu\u1ed1c nh\u01b0 hi\u1ec7n nay.<\/p>\n

Nghi\u00ean c\u1ee9u c\u1ee7a \u0110\u1ea1i h\u1ecdc California San Diego v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Nature Communications. Sau khi th\u1eed nghi\u1ec7m th\u00e0nh c\u00f4ng nh\u1eefng chi\u1ebfc xe t\u00ed hon trong m\u00f4i tr\u01b0\u1eddng \u1ed1ng nghi\u1ec7m, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 d\u00f9ng ch\u00fang \u0111\u1ec3 ph\u00e2n ph\u1ed1i kh\u00e1ng sinh cho chu\u1ed9t. \u0110\u00f3 l\u00e0 nh\u1eefng con chu\u1ed9t b\u1ecb nhi\u1ec5m tr\u00f9ng v\u00e0 lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, m\u00e0 th\u1ee7 ph\u1ea1m l\u00e0 m\u1ed9t lo\u1ea1i vi khu\u1ea9n c\u00f3 t\u00ean Helicobacter pylori.<\/p>\n

M\u1ed9t lo\u1ea1i kh\u00e1ng sinh, clarithromycin, \u0111\u01b0\u1ee3c \u0111\u1eb7t v\u00e0o trong chi\u1ebfc xe giao h\u00e0ng ch\u1ec9 c\u00f3 \u0111\u01b0\u1eddng k\u00ednh b\u1eb1ng n\u1eeda s\u1ee3i t\u00f3c. M\u1ed9t khi chi\u1ebfc xe \u0111i v\u00e0o b\u00ean trong c\u01a1 th\u1ec3, l\u00f5i magie c\u1ee7a n\u00f3 s\u1ebd ph\u1ea3n \u1ee9ng v\u1edbi n\u01b0\u1edbc v\u00e0 gi\u1ea3i ph\u00f3ng m\u1ed9t d\u00f2ng kh\u00ed hydro. D\u00f2ng kh\u00ed t\u1ea1o th\u00e0nh nh\u1eefng bong b\u00f3ng, l\u00e0m nhi\u1ec7m v\u1ee5 nh\u01b0 m\u1ed9t \u0111\u1ed9ng c\u01a1 \u0111\u1ea9y truy\u1ec1n \u0111\u1ed9ng cho chi\u1ebfc xe giao thu\u1ed1c.<\/p>\n

B\u1edfi magie l\u00e0 m\u1ed9t kim lo\u1ea1i nh\u00f3m ki\u1ec1m th\u1ed5, khi ph\u1ea3n \u1ee9ng v\u00e0 \u0111i qua d\u1ea1 d\u00e0y, n\u00f3 c\u0169ng t\u1ea1m th\u1eddi l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 axit t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng. Sau 5 ng\u00e0y \u0111i\u1ec1u tr\u1ecb cho nh\u1eefng con chu\u1ed9t, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e1nh gi\u00e1 ph\u01b0\u01a1ng ph\u00e1p m\u1edbi an to\u00e0n v\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 nh\u1ec9nh h\u01a1n nh\u1eefng c\u00e1ch x\u1eed l\u00fd axit d\u1ea1 d\u00e0y hi\u1ec7n nay, v\u00ed d\u1ee5 nh\u01b0 d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton.<\/p>\n

T\u1eeb l\u00e2u, ch\u00fang ta \u0111\u00e3 bi\u1ebft nhi\u1ec1u \u0111\u1ebfn thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton nh\u01b0 Omeprazole, Pantoprazole v\u00e0 Rabeprazone, d\u00f9ng \u0111\u1ec3 h\u1ea1 n\u1ed3ng \u0111\u1ed9 axit d\u1ea1 d\u00e0y. Th\u1ebf nh\u01b0ng, nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y l\u00e0 kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng \u1edf li\u1ec1u cao v\u00e0 l\u00e2u d\u00e0i. Ch\u00fang c\u0169ng c\u00f3 nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 v\u1edbi gan, h\u1ec7 ti\u00eau h\u00f3a, th\u1ea7n kinh v\u00e0 m\u00e1u.<\/p>\n

Ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng c\u00e1c c\u1ed7 xe si\u00eau nh\u1ecf c\u1ee7a \u0110\u1ea1i h\u1ecdc California San Diego c\u00f3 th\u1ec3 l\u00e0 \u1ee9ng vi\u00ean ti\u1ec1m n\u0103ng thay th\u1ebf nhi\u1ec7m v\u1ee5 c\u1ee7a c\u00e1c lo\u1ea1i thu\u1ed1c \u1ee9c ch\u1ebf proton. V\u1edbi \u0111\u1ed9 an to\u00e0n cao, c\u00e1c nh\u00e0 khoa h\u1ecdc quan s\u00e1t nh\u1eefng con chu\u1ed9t \u0111\u00e3 kh\u00f4i ph\u1ee5c \u0111\u01b0\u1ee3c \u0111\u1ed9 pH d\u1ea1 d\u00e0y ch\u1ec9 trong 1 ng\u00e0y.<\/p>\n

C\u00e1c c\u1ed7 m\u00e1y giao thu\u1ed1c n\u00e0y ch\u00ednh l\u00e0 v\u00ed d\u1ee5 c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1ed9t b\u01b0\u1edbc duy nh\u1ea5t. N\u00f3 k\u1ebft h\u1ee3p hai b\u01b0\u1edbc trung h\u00f2a axit v\u1edbi \u0111i\u1ec1u tr\u1ecb kh\u00e1ng sinh c\u00f9ng l\u00fac, Berta Esteban-Fern\u00e1ndez de \u00c1vila nh\u00e0 nghi\u00ean c\u1ee9u t\u1eeb \u0110\u1ea1i h\u1ecdc California San Diego cho bi\u1ebft.<\/p>\n

Trong b\u1ed1i c\u1ea3nh vi khu\u1ea9n ng\u00e0y c\u00e0ng tr\u1edf n\u00ean kh\u00e1ng kh\u00e1ng sinh, vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c sao cho hi\u1ec7u qu\u1ea3 \u0111ang \u0111\u01b0\u1ee3c quan t\u00e2m h\u01a1n bao gi\u1edd h\u1ebft. C\u00f4ng tr\u00ecnh m\u1edbi c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc c\u00f3 th\u1ec3 gi\u00fap ch\u00fang ta ph\u00e1t tri\u1ec3n c\u00e1c c\u00e1ch \u0111i\u1ec1u tr\u1ecb t\u1ed1t h\u01a1n v\u1edbi thu\u1ed1c kh\u00e1ng sinh, ch\u00ednh x\u00e1c v\u00e0 \u00edt g\u00e2y h\u1ea1i cho c\u01a1 th\u1ec3.<\/p>\n

Tham kh\u1ea3o Motherboard<\/em><\/p>\n

genk.vn<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Nh\u1eefng c\u1ed7 xe t\u00ed hon v\u1eadn chuy\u1ec3n kh\u00e1ng sinh an to\u00e0n qua m\u00f4i tr\u01b0\u1eddng axit d\u1ea1 d\u00e0y M\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 ph\u00e1 h\u1ee7y t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c kh\u00e1ng sinh, kh\u00f4ng ph\u1ea3i si\u00eau vi khu\u1ea9n, m\u00e0 l\u00e0 ch\u00ednh axit trong d\u1ea1 d\u00e0y. C\u00e1c lo\u1ea1i thu\u1ed1c nh\u1ea1y c\u1ea3m v\u1edbi axit \u0111\u00f4i khi tr\u1edf n\u00ean kh\u00f4ng hi\u1ec7u […]<\/p>\n","protected":false},"author":17,"featured_media":6350,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-6105","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=6105"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6105\/revisions"}],"predecessor-version":[{"id":6351,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6105\/revisions\/6351"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/6350"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=6105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=6105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=6105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}