{"id":6058,"date":"2017-08-17T19:25:43","date_gmt":"2017-08-17T12:25:43","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=6058"},"modified":"2017-10-03T09:37:23","modified_gmt":"2017-10-03T02:37:23","slug":"cay-te-bao-nao-lon-vao-nao-nguoi-de-dieu-tri-benh-parkinson","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/cay-te-bao-nao-lon-vao-nao-nguoi-de-dieu-tri-benh-parkinson\/","title":{"rendered":"C\u1ea5y t\u1ebf b\u00e0o n\u00e3o l\u1ee3n v\u00e0o n\u00e3o ng\u01b0\u1eddi \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Parkinson"},"content":{"rendered":"

Trong n\u1ed7 l\u1ef1c ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a b\u1ec7nh \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc Parkinson, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 ngh\u0129 ra m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p t\u00e1o b\u1ea1o, c\u1ea5y t\u1ebf b\u00e0o l\u1ee3n v\u00e0o n\u00e3o h\u1ecd. M\u1eb7c d\u00f9 c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y ch\u1ec9 \u0111ang trong giai \u0111o\u1ea1n \u0111\u1ea7u nh\u01b0ng k\u1ebft qu\u1ea3 th\u1eed nghi\u1ec7m tr\u00ean 4 ng\u01b0\u1eddi kh\u00e1 kh\u1ea3 quan khi t\u00ecnh h\u00ecnh s\u1ee9c kho\u1ebb \u0111\u1ec1u c\u00f3 c\u1ea3i thi\u1ec7n sau 18 th\u00e1ng ph\u1eabu thu\u1eadt.<\/strong><\/p>\n

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\u1ede ng\u01b0\u1eddi m\u1eafc b\u1ec7nh Parkinson, d\u1ea5u hi\u1ec7u r\u00f5 r\u00e0ng nh\u1ea5t \u1edf h\u1ecd l\u00e0 tay ch\u00e2n run r\u1ea9y, kh\u00f3 c\u1eed \u0111\u1ed9ng v\u00e0 th\u01b0\u1eddng t\u1ec7 h\u01a1n theo th\u1eddi gian. Nguy\u00ean nh\u00e2n c\u1ee7a c\u0103n b\u1ec7nh n\u00e0y xu\u1ea5t ph\u00e1t t\u1ef1 s\u1ef1 m\u1ea5t m\u00e1t d\u1ea7n d\u1ea7n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o n\u00e3o \u0111\u00f3ng vai tr\u00f2 s\u1ea3n xu\u1ea5t dopamine, m\u1ed9t h\u1ee3p ch\u1ea5t gi\u00fap ki\u1ec3m so\u00e1t v\u1eadn \u0111\u1ed9ng. Nh\u1eefng lo\u1ea1i thu\u1ed1c hi\u1ec7n c\u00f3 tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 t\u00e1c d\u1ee5ng b\u00f9 \u0111\u1eafp cho dopamine b\u1ecb thi\u1ebfu, nh\u01b0ng hi\u1ec7u qu\u1ea3 c\u1ee7a ch\u00fang l\u1ea1i th\u01b0\u1eddng gi\u1ea3m d\u1ea7n theo th\u1eddi gian.<\/p>\n

Ch\u00ednh v\u00ec v\u1eady, c\u00e1c chuy\u00ean gia \u0111\u1ebfn t\u1eeb c\u00f4ng ty c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o s\u1ed1ng Living Cell Technologies c\u00f3 tr\u1ee5 s\u1edf t\u1ea1i New Zealand \u0111\u00e3 v\u00e0 \u0111ang ph\u00e1t tri\u1ec3n m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ho\u1ea1t \u0111\u1ed9ng nh\u1edd c\u00e1c t\u1ebf b\u00e0o nang \u0111\u00e1m r\u1ed1i m\u00e0ng m\u1ea1ch \u1edf l\u1ee3n. C\u1ea5u tr\u00fac n\u00e0y \u1edf n\u00e3o c\u1ee7a l\u1ee3n ch\u1ecbu tr\u00e1ch nhi\u1ec7m t\u1ea1o ra h\u1ed7n h\u1ee3p c\u00e1c ch\u1ea5t k\u00edch th\u00edch t\u0103ng tr\u01b0\u1edfng c\u00f9ng c\u00e1c t\u00edn hi\u1ec7u ph\u00e2n t\u1eed gi\u00fap \u0111\u1ea3m b\u1ea3o cho s\u1ef1 kho\u1ebb m\u1ea1nh c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh.<\/p>\n

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Th\u00e1ng tr\u01b0\u1edbc, ph\u1eabu thu\u1eadt c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u00e0nh c\u00f4ng tr\u00ean 18 \u0111\u1ed1i t\u01b0\u1ee3ng kh\u00e1c nh\u1eb1m ki\u1ec3m tra xem l\u1ea7n th\u1eed nghi\u1ec7m tr\u01b0\u1edbc c\u00f3 ph\u1ea3i ch\u1ec9 l\u00e0 hi\u1ec7u \u1ee9ng gi\u1ea3 d\u01b0\u1ee3c hay kh\u00f4ng. C\u00e1c nh\u00e0 khoa h\u1ecdc k\u1ef3 v\u1ecdng h\u1ee3p ch\u1ea5t \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi nh\u1eefng t\u1ebf b\u00e0o n\u00e0y s\u1ebd gi\u00fap nu\u00f4i d\u01b0\u1ee1ng nh\u1eefng t\u1ebf b\u00e0o dopamine c\u00f2n l\u1ea1i trong n\u00e3o c\u1ee7a b\u1ec7nh nh\u00e2n Parkinson, \u0111\u1ed3ng th\u1eddi l\u00e0m ch\u1eadm l\u1ea1i qu\u00e1 tr\u00ecnh m\u1ea5t m\u00e1t. “M\u1ed9t nh\u00e0 m\u00e1y ho\u00e1 h\u1ecdc th\u1ea7n kinh nh\u1ecf \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o \u0111\u1ec3 th\u00fac \u0111\u1ea9y s\u1ef1 t\u0103ng tr\u01b0\u1edfng c\u1ee7a t\u1ebf b\u00e0o th\u1ea7n kinh m\u1edbi v\u00e0 s\u1eeda ch\u1eefa”, Ken Taylor \u0111\u1ebfn t\u1eeb Living Cell Technologies cho bi\u1ebft.<\/p>\n

\u0110\u1ec3 ti\u1ebfn h\u00e0nh ph\u1eabu thu\u1eadt, c\u00e1c nh\u00e0 khoa h\u1ecdc b\u1eaft \u0111\u1ea7u cho t\u1ebf b\u00e0o l\u1ee3n v\u00e0o m\u1ed9t v\u1ecf b\u1ecdc x\u1ed1p \u0111\u01b0\u1ee3c l\u00e0m t\u1eeb t\u1ea3o, cho ph\u00e9p c\u00e1c ch\u1ea5t k\u00edch th\u00edch t\u0103ng tr\u01b0\u1edfng di chuy\u1ec3n v\u00e0o v\u00f9ng xung quanh m\u00f4 n\u00e3o, \u0111\u1ed3ng th\u1eddi ng\u0103n ch\u1eb7n s\u1ef1 t\u1ea5n c\u00f4ng c\u1ee7a c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch tr\u00ean c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n. \u0110\u01b0\u1ee3c bi\u1ebft bi\u1ec7n ph\u00e1p n\u00e0y c\u0169ng \u0111ang \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u00e1p d\u1ee5ng cho nh\u1eefng ng\u01b0\u1eddi b\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng nh\u01b0ng t\u1ebf b\u00e0o c\u1ea5y v\u00e0o c\u01a1 th\u1ec3 h\u1ecd l\u00e0 t\u1ebf b\u00e0o t\u1ee5y l\u1ee3n. M\u1ed7i m\u1ed9t vi\u00ean con nh\u1ed9ng r\u1ed9ng kho\u1ea3ng 1\/2mm v\u00e0 c\u00f3 ch\u1ee9a h\u00e0ng ng\u00e0n t\u1ebf b\u00e0o l\u1ee3n b\u00ean trong. \u1ede th\u1eed nghi\u1ec7m nh\u1ecf \u0111\u1ea7u ti\u00ean, 40 vi\u00ean con nh\u1ed9ng \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o m\u1ed9t b\u00ean n\u00e3o c\u1ee7a b\u1ed1n b\u1ec7nh nh\u00e2n kh\u00e1c nhau.<\/p>\n

Sau qu\u00e1 tr\u00ecnh th\u1eed nghi\u1ec7m, c\u00e1c nh\u00e0 khoa h\u1ecdc nh\u1eadn th\u1ea5y r\u00f5 r\u00e0ng c\u00f3 s\u1ef1 c\u1ea3i thi\u1ec7n trong vi\u1ec7c l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u1ed9 tr\u1ea7m tr\u1ecdng c\u1ee7a c\u00e1c tri\u1ec7u ch\u1ee9ng. Tuy nhi\u00ean, Steven Gill \u0111\u1ebfn t\u1eeb \u0110\u1ea1i h\u1ecdc Bristol (Anh) cho r\u1eb1ng k\u1ebft qu\u1ea3 c\u00f3 th\u1ec3 xu\u1ea5t ph\u00e1t t\u1eeb hi\u1ec7u \u1ee9ng gi\u1ea3 d\u01b0\u1ee3c, b\u1edfi theo \u00f4ng, t\u1ed1c \u0111\u1ed9 ph\u1ee5c h\u1ed3i c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh kh\u00f4ng nhanh. Tr\u01b0\u1edbc \u0111\u00e2y, t\u1eebng c\u00f3 nhi\u1ec1u nghi\u00ean c\u1ee9u ph\u00e1t hi\u1ec7n ra r\u1eb1ng c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh Parkinson d\u01b0\u1eddng nh\u01b0 c\u00f3 m\u1ed9t ph\u1ea3n \u1ee9ng \u0111\u1eb7c bi\u1ec7t v\u1edbi hi\u1ec7u \u1ee9ng gi\u1ea3 d\u01b0\u1ee3c, khi nhi\u1ec1u ng\u01b0\u1eddi cho r\u1eb1ng t\u00ecnh tr\u1ea1ng b\u1ec7nh c\u1ee7a h\u1ecd c\u1ea3i thi\u1ec7n nhi\u1ec1u h\u01a1n so v\u1edbi mong \u0111\u1ee3i.<\/p>\n

Gill c\u0169ng ho\u00e0i nghi v\u1ec1 t\u1ed1c \u0111\u1ed9 c\u1ea3i thi\u1ec7n c\u1ee7a c\u00e1c tri\u1ec7u ch\u1ee9ng b\u1edfi \u00f4ng cho r\u1eb1ng m\u1ee9c \u0111\u1ed9 tr\u1ea7m tr\u1ecdng c\u1ee7a ch\u00fang ban \u0111\u1ea7u \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00f3ng \u0111\u1ea1i. Tuy nhi\u00ean, m\u1ed9t th\u1eed nghi\u1ec7m l\u1edbn h\u01a1n nh\u1eb1m ki\u1ec3m tra li\u1ec7u \u0111\u00e2y c\u00f3 ph\u1ea3i l\u00e0 m\u1ed9t hi\u1ec7u \u1ee9ng gi\u1ea3 d\u01b0\u1ee3c hay kh\u00f4ng s\u1ebd l\u00e0m s\u00e1ng t\u1ecf h\u01a1n v\u1ea5n \u0111\u1ec1 n\u00e0y. K\u1ebft qu\u1ea3 c\u1ee7a th\u1eed nghi\u1ec7m \u0111\u01b0\u1ee3c cho l\u00e0 s\u1ebd \u0111\u01b0\u1ee3c ho\u00e0n th\u00e0nh v\u00e0o th\u00e1ng 11 n\u0103m nay. Trong th\u1eed nghi\u1ec7m n\u00e0y, 120 vi\u00ean con nh\u1ed9ng s\u1ebd \u0111\u01b0\u1ee3c \u0111\u1eb7t v\u00e0o c\u1ea3 hai b\u00ean n\u00e3o c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n

Roger Barker thu\u1ed9c \u0110\u1ea1i h\u1ecdc Cambridge, ng\u01b0\u1eddi tr\u01b0\u1edbc \u0111\u00e2y \u0111\u00e3 t\u1eebng l\u00e0 c\u1ed1 v\u1ea5n khoa h\u1ecdc c\u1ee7a c\u00f4ng ty, cho r\u1eb1ng chi\u1ebfn l\u01b0\u1ee3c m\u00e0 nh\u00f3m nghi\u00ean c\u1ee9u \u0111ang th\u1ef1c hi\u1ec7n l\u00e0 m\u1ed9t \u00fd t\u01b0\u1edfng hay nh\u01b0ng \u00f4ng s\u1ebd kh\u00f4ng tham gia v\u00e0o qu\u00e1 tr\u00ecnh th\u1eed nghi\u1ec7m hi\u1ec7n t\u1ea1i. “C\u00e2u h\u1ecfi \u0111\u1eb7t ra l\u00e0 m\u1ee9c \u0111\u1ed9 c\u1ea1nh tranh c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p n\u00e0y so v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o kh\u00e1c”.<\/p>\n

Tr\u01b0\u1edbc \u0111\u00e2y, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1eebng g\u1eb7t h\u00e1i \u0111\u01b0\u1ee3c m\u1ed9t s\u1ed1 th\u00e0nh c\u00f4ng nh\u1ea5t \u0111\u1ecbnh v\u1edbi vi\u1ec7c c\u1ea5y c\u00e1c t\u1ebf b\u00e0o l\u1ea5y t\u1eeb b\u00e0o thai b\u1ecb s\u1ea9y v\u00e0o n\u00e3o b\u1ec7nh nh\u00e2n \u0111\u1ec3 s\u1ea3n su\u1ea5t dopamine. Tuy nhi\u00ean, vi\u1ec7c thu ho\u1ea1ch nh\u1eefng t\u1ebf b\u00e0o nh\u01b0 v\u1eady kh\u00f4ng ph\u1ea3i l\u00fac n\u00e0o c\u0169ng d\u1ec5 d\u00e0ng. Ngo\u00e0i ra, c\u00e1c chuy\u00ean gia c\u0169ng \u0111ang k\u1ef3 v\u1ecdng v\u00e0o nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p gi\u00fap bi\u1ebfn t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh th\u00e0nh t\u1ebf b\u00e0o c\u00f3 th\u1ec3 s\u1ea3n sinh dopamine. N\u1ebfu th\u00e0nh c\u00f4ng, li\u1ec7u ph\u00e1p n\u00e0y s\u1ebd tr\u1edf n\u00ean an to\u00e0n r\u1ea5t nhi\u1ec1u do n\u00f3 kh\u00f4ng b\u1ecb \u0111\u00e0o th\u1ea3i b\u1edfi h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a con ng\u01b0\u1eddi.<\/p>\n

B\u00ean c\u1ea1nh Parkinson, t\u1ebf b\u00e0o n\u00e3o l\u1ee3n c\u0169ng \u0111ang \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nh\u1eefng c\u0103n b\u1ec7nh th\u1ea7n kinh kh\u00e1c trong \u0111\u00f3 bao g\u1ed3m c\u1ea3 Alzheimer v\u00e0 Huntington. M\u1eb7c d\u00f9 cho \u0111\u1ebfn nay \u0111\u00e3 c\u00f3 nh\u1eefng th\u00e0nh c\u00f4ng nh\u1ea5t \u0111\u1ecbnh v\u1edbi li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o l\u1ee3n, tuy nhi\u00ean vi\u1ec7c c\u00e2y gh\u00e9p t\u1eeb \u0111\u1ed9ng v\u1eadt sang ng\u01b0\u1eddi v\u1eabn t\u1ed3n t\u1ea1i nh\u1eefng nguy c\u01a1 kh\u00f3 l\u01b0\u1eddng tr\u01b0\u1edbc \u0111\u01b0\u1ee3c, \u0111i\u1ec3n h\u00ecnh l\u00e0 m\u1ed1i lo v\u1ec1 lo\u1ea1i virus ng\u1ee7 y\u00ean trong DNA l\u1ee3n – \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 retrovirus n\u1ed9i sinh l\u1ee3n, c\u00f3 th\u1ea3 n\u0103ng l\u00e2y lan sang ng\u01b0\u1eddi v\u00e0 h\u00ecnh th\u00e0nh m\u1ed9t c\u0103n b\u1ec7nh m\u1edbi.<\/p>\n

Tuy v\u1eady, \u0111i\u1ec1u n\u00e0y v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf nh\u1eefng ng\u01b0\u1eddi nh\u1eadn t\u1ebf b\u00e0o t\u1ee5y l\u1ee3n \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. Nh\u1eb1m lo\u1ea1i b\u1ecf tri\u1ec7t \u0111\u1ec3 nguy c\u01a1 n\u00e0y, m\u1ed9t nh\u00f3m c\u00e1c nh\u00e0 khoa h\u1ecdc kh\u00e1c c\u0169ng \u0111ang c\u1ed1 g\u1eafng s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 ch\u1ec9nh s\u1eeda gen CRISPR \u0111\u1ec3 x\u00f3a \u0111i nh\u1eefng virus nguy hi\u1ec3m ra kh\u1ecfi b\u1ed9 gen l\u1ee3n.<\/p>\n

Tham kh\u1ea3o: NewScientist\u200b<\/em><\/p>\n

tinhte.vn<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Trong n\u1ed7 l\u1ef1c ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a b\u1ec7nh \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc Parkinson, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 ngh\u0129 ra m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p t\u00e1o b\u1ea1o, c\u1ea5y t\u1ebf b\u00e0o l\u1ee3n v\u00e0o n\u00e3o h\u1ecd. M\u1eb7c d\u00f9 c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y ch\u1ec9 \u0111ang trong giai \u0111o\u1ea1n \u0111\u1ea7u nh\u01b0ng k\u1ebft qu\u1ea3 th\u1eed nghi\u1ec7m tr\u00ean 4 ng\u01b0\u1eddi kh\u00e1 […]<\/p>\n","protected":false},"author":17,"featured_media":6369,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-6058","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6058","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=6058"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6058\/revisions"}],"predecessor-version":[{"id":6372,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/6058\/revisions\/6372"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/6369"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=6058"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=6058"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=6058"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}