{"id":5467,"date":"2016-05-31T14:41:22","date_gmt":"2016-05-31T07:41:22","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=5467"},"modified":"2017-10-02T15:01:22","modified_gmt":"2017-10-02T08:01:22","slug":"cac-nha-khoa-hoc-da-tim-ra-cach-ngan-chan-ung-thu-vu-tai-phat","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/cac-nha-khoa-hoc-da-tim-ra-cach-ngan-chan-ung-thu-vu-tai-phat\/","title":{"rendered":"C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u00ecm ra c\u00e1ch ng\u0103n ch\u1eb7n ung th\u01b0 v\u00fa t\u00e1i ph\u00e1t"},"content":{"rendered":"

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc Duke (M\u1ef9) \u0111\u00e3 c\u00f3 th\u1ec3 ng\u0103n ch\u1eb7n th\u00e0nh c\u00f4ng qu\u00e1 tr\u00ecnh x\u00e2m nh\u1eadp v\u00e0 \u1ea9n n\u00e1u c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa v\u00e0o trong x\u01b0\u01a1ng chu\u1ed9t, n\u01a1i ch\u00fang c\u00f3 th\u1ec3 s\u1ed1ng s\u00f3t qua c\u00e1c \u0111\u1ee3t h\u00f3a tr\u1ecb. Nh\u00f3m nh\u00e0 khoa h\u1ecdc c\u0169ng \u0111\u00e3 ngh\u0129 ra m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ec3 \u2018\u0111u\u1ed5i\u2019 c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa ra kh\u1ecfi t\u1ee7y x\u01b0\u01a1ng \u1edf chu\u1ed9t, khi\u1ebfn ch\u00fang d\u1ec5 d\u00e0ng b\u1ecb ti\u00eau di\u1ec7t h\u01a1n b\u1edfi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng ho\u1eb7c nh\u1edd h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch. Th\u00e0nh c\u00f4ng m\u1edbi c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc h\u1ee9a h\u1eb9n cho s\u1ef1 ra \u0111\u1eddi c\u1ee7a m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p t\u01b0\u01a1ng t\u1ef1, c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean c\u01a1 th\u1ec3 ng\u01b0\u1eddi, th\u1eafp l\u00ean hy v\u1ecdng r\u1eb1ng m\u1ed9t ng\u00e0y n\u00e0o \u0111\u00f3, m\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 nguy hi\u1ec3m nh\u1ea5t c\u1ee7a ung th\u01b0 v\u00fa c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ng\u0103n ch\u1eb7n.<\/strong><\/p>\n

\"\"<\/p>\n

\u0110\u1ed1i v\u1edbi nhi\u1ec1u b\u1ec7nh nh\u00e2n, ung th\u01b0 v\u00fa c\u00f3 th\u1ec3 t\u00e1i l\u1ea1i 5 n\u0103m sau th\u1eddi \u0111i\u1ec3m \u0111i\u1ec1u tr\u1ecb, v\u00e0 l\u00e2y lan \u0111\u1ebfn c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3 – m\u1ed9t qu\u00e1 tr\u00ecnh th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 di c\u0103n. C\u00e1c nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y t\u1eebng cho th\u1ea5y t\u1ee7y x\u01b0\u01a1ng c\u00f3 th\u1ec3 l\u00e0 n\u01a1i tr\u00fa \u1ea9n an to\u00e0n trong h\u00f3a tr\u1ecb, ngh\u0129a l\u00e0 c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa c\u00f3 th\u1ec3 n\u1eb1m im trong \u0111\u00f3 su\u1ed1t m\u1ed9t kho\u1ea3ng th\u1eddi gian d\u00e0i m\u00e0 kh\u00f4ng ch\u1ecbu \u1ea3nh h\u01b0\u1edfng b\u1edfi thu\u1ed1c. Tuy nhi\u00ean, cho \u0111\u1ebfn nay, c\u00e1ch th\u1ee9c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa x\u00e2m nh\u1eadp v\u00e0 \u1ea9n trong x\u01b0\u01a1ng v\u1eabn c\u00f2n l\u00e0 \u0111i\u1ec1u ch\u01b0a th\u1ec3 l\u00fd gi\u1ea3i \u0111\u01b0\u1ee3c.<\/p>\n

S\u1eed d\u1ee5ng k\u1ef9 thu\u1eadt k\u00ednh hi\u1ec3n vi theo th\u1eddi gian th\u1ef1c, nh\u00f3m chuy\u00ean gia t\u1ea1i \u0110\u1ea1i h\u1ecdc Duke \u0111\u00e3 theo d\u00f5i s\u1ef1 di chuy\u1ec3n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa, khi ch\u00fang \u0111i qua t\u1ee7y x\u01b0\u01a1ng c\u1ee7a chu\u1ed9t v\u00e0 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c E-selectin ch\u00ednh l\u00e0 lo\u1ea1i protein cho ph\u00e9p c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 \u0111i v\u00e0o t\u1ee7y x\u01b0\u01a1ng, v\u00e0 CXCR4 – protein gi\u00fap ch\u00fang b\u00e1m v\u00e0o x\u01b0\u01a1ng, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n \u0111\u1ec3 \u1ea9n n\u00e1u. \u0110i\u1ec1u tr\u1ecb nh\u1eefng con chu\u1ed9t b\u1eb1ng thu\u1ed1c \u1ee9c ch\u1ebf E-selectin, c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa kh\u00f4ng th\u1ec3 x\u00e2m nh\u1eadp v\u00e0o x\u01b0\u01a1ng, v\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf CXCR4 bu\u1ed9c ch\u00fang quay tr\u1edf l\u1ea1i m\u00e1u.<\/p>\n

Ph\u00f3 gi\u00e1o s\u01b0 Dorothy Sipkins t\u1ea1i \u0110\u1ea1i h\u1ecdc Duke, cho bi\u1ebft: \u201cC\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u00e3 cho th\u1ea5y ung th\u01b0 v\u00fa c\u00f3 th\u1ec3 s\u1edbm \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n c\u0169ng nh\u01b0 \u0111i\u1ec1u tr\u1ecb, v\u00e0 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 s\u1ebd kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u c\u1ee7a b\u1ec7nh. Sau \u0111\u00f3 5 n\u0103m, 10 n\u0103m ho\u1eb7c th\u1eadm ch\u00ed l\u00e0 15 n\u0103m, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 t\u00e1i ph\u00e1t. Th\u00f4ng th\u01b0\u1eddng, x\u01b0\u01a1ng s\u1ebd l\u00e0 n\u01a1i m\u00e0 ung th\u01b0 di c\u0103n. V\u00e0 b\u00e2y gi\u1edd ch\u00fang t\u00f4i \u0111\u00e3 bi\u1ebft \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch n\u00e0o t\u1ebf b\u00e0o ung th\u01b0 \u0111i v\u00e0o \u0111\u00f3, \u0111\u1ed3ng th\u1eddi c\u0169ng x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c m\u1ed9t c\u01a1 ch\u1ebf quan tr\u1ecdng cho ph\u00e9p ch\u00fang \u2018neo\u2019 v\u00e0o trong t\u1ee7y x\u01b0\u01a1ng. \u0110\u1ed1i v\u1edbi chu\u1ed9t, nh\u1eefng ph\u00e1t hi\u1ec7n c\u1ee7a ch\u00fang t\u00f4i c\u00f3 th\u1ec3 cung c\u1ea5p c\u00e1c chi\u1ebfn l\u01b0\u1ee3c m\u1edbi nh\u1eb1m can thi\u1ec7p \u1edf c\u1ea5p \u0111\u1ed9 ph\u00e2n t\u1eed, tr\u01b0\u1edbc khi c\u00e1c t\u1ebf b\u00e0o n\u1eb1m im \u0111\u00f3 c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng v\u00e0 tr\u1edf th\u00e0nh nguy\u00ean nh\u00e2n g\u00e2y t\u00e1i ph\u00e1t b\u1ec7nh\u201d.<\/p>\n

C\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf E-selectin s\u1eed d\u1ee5ng trong nghi\u00ean \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 GMI-1271, \u0111ang \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean con ng\u01b0\u1eddi. Gi\u00e1o s\u01b0 Sipkins cho bi\u1ebft c\u00f4 hy v\u1ecdng c\u00f3 th\u1ec3 ti\u1ebfn h\u00e0nh th\u00eam c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean chu\u1ed9t, \u0111\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 c\u00e1ch c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa di chuy\u1ec3n kh\u1eafp c\u01a1 th\u1ec3, tr\u01b0\u1edbc khi chuy\u1ec3n sang nghi\u00ean c\u1ee9u qu\u00e1 tr\u00ecnh n\u00e0y \u1edf con ng\u01b0\u1eddi.<\/p>\n

Theo: Telegraph, \u1ea2nh minh h\u1ecda: Ibtimes\u200b<\/em><\/strong><\/p>\n

Ngu\u1ed3n tinhte.vn<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc Duke (M\u1ef9) \u0111\u00e3 c\u00f3 th\u1ec3 ng\u0103n ch\u1eb7n th\u00e0nh c\u00f4ng qu\u00e1 tr\u00ecnh x\u00e2m nh\u1eadp v\u00e0 \u1ea9n n\u00e1u c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa v\u00e0o trong x\u01b0\u01a1ng chu\u1ed9t, n\u01a1i ch\u00fang c\u00f3 th\u1ec3 s\u1ed1ng s\u00f3t qua c\u00e1c \u0111\u1ee3t h\u00f3a tr\u1ecb. Nh\u00f3m nh\u00e0 khoa h\u1ecdc c\u0169ng \u0111\u00e3 ngh\u0129 ra m\u1ed9t ph\u01b0\u01a1ng […]<\/p>\n","protected":false},"author":17,"featured_media":5505,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-5467","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/5467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=5467"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/5467\/revisions"}],"predecessor-version":[{"id":5506,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/5467\/revisions\/5506"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/5505"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=5467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=5467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=5467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}