{"id":4584,"date":"2015-11-24T07:08:57","date_gmt":"2015-11-24T00:08:57","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=4584"},"modified":"2017-10-02T09:36:05","modified_gmt":"2017-10-02T02:36:05","slug":"tim-ra-phuong-phap-tieu-diet-vi-khuan-trong-co-the-hoan-toan-moi","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/tim-ra-phuong-phap-tieu-diet-vi-khuan-trong-co-the-hoan-toan-moi\/","title":{"rendered":"T\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p ti\u00eau di\u1ec7t vi khu\u1ea9n trong c\u01a1 th\u1ec3 ho\u00e0n to\u00e0n m\u1edbi"},"content":{"rendered":"

C\u00e1c nh\u00e0 khoa h\u1ecdc M\u1ef9 t\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p t\u1ea1o ra c\u00e1c chi\u1ebfn binh b\u1ea3o v\u1ec7 h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 v\u1edbi kh\u00e1ng sinh, khi\u1ebfn vi khu\u1ea9n trong t\u1ebf b\u00e0o th\u00e0nh m\u1ee5c ti\u00eau t\u1ea5n c\u00f4ng.<\/strong><\/p>\n

\"\"<\/p>\n

Theo m\u00f4 t\u1ea3 nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Nature, nh\u00f3m chuy\u00ean gia c\u1ee7a c\u00f4ng ty c\u00f4ng ngh\u1ec7 sinh h\u1ecdc Genentech li\u00ean k\u1ebft m\u1ed9t kh\u00e1ng th\u1ec3 v\u1edbi d\u1eabn xu\u1ea5t c\u1ee7a m\u1ed9t nh\u00f3m kh\u00e1ng sinh g\u1ecdi l\u00e0 rifamycin. N\u00f3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 ph\u01b0\u01a1ng ph\u00e1p m\u1edbi nh\u1eb1m ti\u00eau di\u1ec7t t\u1ee5 c\u1ea7u khu\u1ea9n (Staphylococcus aureus) trong t\u1ebf b\u00e0o. Trong t\u01b0\u01a1ng lai, ch\u00fang ta c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng k\u1ef9 thu\u1eadt n\u00e0y \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u00f3 vi khu\u1ea9n b\u1ea5t th\u01b0\u1eddng trong m\u00e1u v\u00e0 \u0111\u1ec1 kh\u00e1ng kh\u00e1ng sinh.<\/p>\n

Staphylococcus aureus kh\u00e1 ph\u1ed5 bi\u1ebfn, th\u01b0\u1eddng t\u1eadp trung v\u00f9ng quanh m\u0169i. S\u1ebd kh\u00f4ng c\u00f3 v\u1ea5n \u0111\u1ec1 nghi\u00eam tr\u1ecdng tr\u1eeb khi ch\u00fang g\u00e2y nhi\u1ec5m khu\u1ea9n n\u1eb7ng v\u00e0 l\u1eb7p \u0111i l\u1eb7p l\u1ea1i, c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u1eed vong. M\u1ed9t s\u1ed1 d\u00f2ng c\u00f3 th\u1ec3 \u0111\u1ec1 kh\u00e1ng t\u1ef1 nhi\u00ean v\u1edbi thu\u1ed1c kh\u00e1ng sinh th\u00f4ng th\u01b0\u1eddng, trong \u0111\u00f3 t\u1ee5 c\u1ea7u khu\u1ea9n MRSA g\u00e2y 80.000 ca nhi\u1ec5m v\u00e0 11.285 tr\u01b0\u1eddng h\u1ee3p t\u1eed vong m\u1ed7i n\u0103m. \u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u mu\u1ed1n t\u00ecm c\u00e1ch ti\u00eau di\u1ec7t m\u1ea7m b\u1ec7nh t\u1eeb khi n\u00f3 c\u00f2n trong t\u1ebf b\u00e0o, n\u01a1i \u1ea9n n\u00e1u m\u00e0 kh\u00e1ng sinh ch\u1ed1ng t\u1ee5 c\u1ea7u khu\u1ea9n kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/p>\n

“T\u1ee5 c\u1ea7u khu\u1ea9n c\u00f3 th\u1ec3 \u1ea9n b\u00ean trong t\u1ebf b\u00e0o m\u00e1u v\u00e0i gi\u1edd ho\u1eb7c v\u00e0i ng\u00e0y, sau \u0111\u00f3 ph\u00e1t tri\u1ec3n m\u1ea1nh v\u00e0 l\u00e2y lan sang t\u1ebf b\u00e0o kh\u00e1c”, nh\u00e0 sinh h\u1ecdc Sanjeev Mariathasan cho hay. \u0110\u00e2y l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 l\u1edbn b\u1edfi thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 ch\u1ed1ng nhi\u1ec5m khu\u1ea9n th\u01b0\u1eddng c\u00f3 t\u00e1c d\u1ee5ng trong kho\u1ea3ng 4 gi\u1edd, l\u00e2u h\u01a1n nhi\u1ec1u so v\u1edbi th\u1eddi gian vi khu\u1ea9n lan sang t\u1ebf b\u00e0o m\u1edbi. Theo Mariathasan, trong nghi\u00ean c\u1ee9u v\u1edbi chu\u1ed9t, lo\u00e0i \u0111\u1ed9ng v\u1eadt n\u00e0y ph\u1ee5c h\u1ed3i nhanh h\u01a1n v\u00e0 \u00edt ch\u1ecbu t\u00e1c \u0111\u1ed9ng ti\u00eau c\u1ef1c.<\/p>\n

Trong nh\u1eefng n\u0103m qua, Genentech \u0111\u00e3 t\u1ea1o ra c\u00e1c kh\u00e1ng th\u1ec3 c\u00f3 th\u1ec3 ch\u1ed1ng l\u1ea1i t\u00e1c nh\u00e2n l\u1ea1 nh\u01b0 t\u1ee5 c\u1ea7u khu\u1ea9n. C\u00e1c nh\u00e0 khoa h\u1ecdc k\u1ebft h\u1ee3p kh\u00e1ng sinh v\u1edbi kh\u00e1ng th\u1ec3 b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng axit amin nh\u01b0 m\u1ed9t lo\u1ea1i keo. Khi k\u1ebft h\u1ee3p l\u1ea1i, ph\u01b0\u01a1ng ph\u00e1p tr\u00ean h\u1ee9a h\u1eb9n \u0111em l\u1ea1i hi\u1ec7u qu\u1ea3 cao h\u01a1n so v\u1edbi kh\u00e1ng sinh th\u00f4ng th\u01b0\u1eddng.<\/p>\n

Gerald Pier, m\u1ed9t nh\u00e0 vi sinh v\u1eadt h\u1ecdc t\u1ea1i \u0110\u1ea1i h\u1ecdc Harvard, cho r\u1eb1ng nh\u00f3m chuy\u00ean gia c\u1ea7n ch\u1ee9ng minh r\u1eb1ng n\u00f3 c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng v\u1edbi nhi\u1ec1u ch\u1ee7ng vi khu\u1ea9n kh\u00e1c nhau. Gi\u1edbi nghi\u00ean c\u1ee9u hi\u1ec7n ch\u01b0a th\u1ec3 k\u1ebft lu\u1eadn t\u1ee5 c\u1ea7u khu\u1ea9n trong t\u1ebf b\u00e0o c\u00f3 ph\u1ea3i nguy\u00ean nh\u00e2n g\u00e2y nhi\u1ec5m khu\u1ea9n l\u1eb7p l\u1ea1i hay kh\u00f4ng, nh\u01b0ng ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u00f3 th\u1ec3 \u0111\u1eb7t d\u1ea5u ch\u1ea5m h\u1ebft b\u1eb1ng c\u00e1ch d\u1ecdn s\u1ea1ch \u1ed5 vi khu\u1ea9n.<\/p>\n

Tuy nhi\u00ean, nghi\u00ean c\u1ee9u v\u1eabn c\u00f2n m\u1ed9t s\u1ed1 h\u1ea1n ch\u1ebf khi th\u00ed nghi\u1ec7m m\u1edbi ch\u1ec9 th\u1ef1c hi\u1ec7n v\u1edbi c\u01a1 th\u1ec3 chu\u1ed9t v\u00e0 t\u1ebf b\u00e0o trong \u1ed1ng nghi\u1ec7m. Mariathasan t\u1eeb ch\u1ed1i ti\u1ebft l\u1ed9 v\u1ec1 th\u1eddi \u0111i\u1ec3m th\u1eed nghi\u1ec7m, nh\u01b0ng \u00f4ng cho bi\u1ebft Genentech r\u1ea5t quan t\u00e2m \u0111\u1ebfn c\u00e1c k\u1ebft qu\u1ea3 v\u1edbi con ng\u01b0\u1eddi. V\u00ec \u0111\u00e2y l\u00e0 lo\u1ea1i thu\u1ed1c \u0111\u1eb7c bi\u1ec7t, n\u00ean c\u00e1c b\u00e1c s\u0129 s\u1ebd ch\u1ec9 d\u00f9ng n\u00f3 khi b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n c\u1ea9n th\u1eadn.<\/p>\n

Tham kh\u1ea3o TheVerge<\/em><\/p>\n

Ngu\u1ed3n GenK.vn<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 khoa h\u1ecdc M\u1ef9 t\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p t\u1ea1o ra c\u00e1c chi\u1ebfn binh b\u1ea3o v\u1ec7 h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 v\u1edbi kh\u00e1ng sinh, khi\u1ebfn vi khu\u1ea9n trong t\u1ebf b\u00e0o th\u00e0nh m\u1ee5c ti\u00eau t\u1ea5n c\u00f4ng. Theo m\u00f4 t\u1ea3 nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Nature, nh\u00f3m chuy\u00ean gia c\u1ee7a c\u00f4ng ty c\u00f4ng […]<\/p>\n","protected":false},"author":17,"featured_media":5067,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-4584","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=4584"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4584\/revisions"}],"predecessor-version":[{"id":5068,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4584\/revisions\/5068"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/5067"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=4584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=4584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=4584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}