{"id":4172,"date":"2015-10-09T11:45:22","date_gmt":"2015-10-09T04:45:22","guid":{"rendered":"http:\/\/ttud.com.vn\/?p=4172"},"modified":"2017-09-28T22:53:08","modified_gmt":"2017-09-28T15:53:08","slug":"su-ket-hop-ba-loai-thuoc-khang-sinh-co-the-giet-chet-khuan-tu-cau-gay-chet-nguoi","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/su-ket-hop-ba-loai-thuoc-khang-sinh-co-the-giet-chet-khuan-tu-cau-gay-chet-nguoi\/","title":{"rendered":"S\u1ef1 k\u1ebft h\u1ee3p ba lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh c\u00f3 th\u1ec3 gi\u1ebft ch\u1ebft khu\u1ea9n t\u1ee5 c\u1ea7u g\u00e2y ch\u1ebft ng\u01b0\u1eddi."},"content":{"rendered":"

Theo m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi, ba lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh n\u00e0y (n\u1ebfu s\u1eed d\u1ee5ng ri\u00eang l\u1ebb s\u1ebd kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i nhi\u1ec5m t\u1ee5 c\u1ea7u khu\u1ea9n kh\u00e1ng thu\u1ed1c) c\u00f3 th\u1ec3 gi\u1ebft ch\u1ebft c\u00e1c m\u1ea7m b\u1ec7nh ch\u1ebft ng\u01b0\u1eddi khi k\u1ebft h\u1ee3p c\u00f9ng nhau.<\/strong><\/p>\n

\"\"<\/p>\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y Washington, St. Louis \u0111\u00e3 ti\u00eau di\u1ec7t c\u00e1c vi khu\u1ea9n t\u1ee5 c\u1ea7u v\u00e0ng kh\u00e1ng methicillin, Staphylococcus aureus (MRSA) \u2013 trong \u0111i\u1ec3u ki\u1ec7n \u1ed1ng nghi\u1ec7m v\u00e0 tr\u00ean chu\u1ed9t . H\u1ecd tin r\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p k\u1ebft h\u1ee3p ba lo\u1ea1i thu\u1ed1c c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean ng\u01b0\u1eddi.<\/p>\n

” Vi khu\u1ea9n t\u1ee5 c\u1ea7u v\u00e0ng kh\u00e1ng methicillin (MRSA) gi\u1ebft ch\u1ebft 11.000 ng\u01b0\u1eddi m\u1ed7i n\u0103m t\u1ea1i Hoa K\u1ef3, v\u00e0 \u0111\u00e2y l\u00e0 m\u1ea7m b\u1ec7nh \u0111\u01b0\u1ee3c x\u1ebfp l\u00e0 m\u1ed9t trong nh\u1eefng vi khu\u1ea9n kh\u00e1ng thu\u1ed1c nh\u1ea5t tr\u00ean th\u1ebf gi\u1edbi”, nh\u00e0 nghi\u00ean c\u1ee9u ch\u00ednh Gautam Dantas, ti\u1ebfn s\u0129, gi\u00e1o s\u01b0 b\u1ec7nh l\u00fd h\u1ecdc v\u00e0 mi\u1ec5n d\u1ecbch h\u1ecdc cho bi\u1ebft. “S\u1eed d\u1ee5ng k\u1ebft h\u1ee3p thu\u1ed1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb tr\u00ean ng\u01b0\u1eddi c\u00f3 ti\u1ec1m n\u0103ng \u1ee9ng d\u1ee5ng nhanh ch\u00f3ng b\u1edfi v\u00ec t\u1ea5t c\u1ea3 ba lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh \u0111\u1ec1u \u0111\u01b0\u1ee3c s\u1ef1 ch\u1ea5p thu\u1eadn c\u1ee7a FDA.”<\/p>\n

Nghi\u00ean c\u1ee9u n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u1ef1c tuy\u1ebfn ng\u00e0y 14\/09 tr\u00ean t\u1ea1p ch\u00ed Nature Chemical Biology.<\/p>\n

Ba lo\u1ea1i thu\u1ed1c – meropenem, piperacillin v\u00e0 tazobactam – thu\u1ed9c m\u1ed9t ch\u1ee7ng lo\u1ea1i kh\u00e1ng sinh t\u00ean beta-lactam kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i MRSA trong nhi\u1ec1u th\u1eadp k\u1ef7.<\/p>\n

L\u00e0m vi\u1ec7c v\u1edbi c\u00e1c c\u1ed9ng t\u00e1c vi\u00ean trong ph\u00f2ng th\u00ed nghi\u1ec7m vi sinh h\u1ecdc t\u1ea1i B\u1ec7nh vi\u1ec7n Barnes-Jewish \u1edf St. Louis, nh\u00f3m c\u1ee7a Dantas \u0111\u00e3 th\u1eed nghi\u1ec7m v\u00e0 ph\u00e2n t\u00edch v\u1ec1 m\u1eb7t di chuy\u1ec3n h\u1ecdc 73 bi\u1ebfn th\u1ec3 kh\u00e1c nhau c\u1ee7a vi khu\u1ea9n MRSA \u0111\u1ec3 m\u00f4 t\u1ea3 c\u00e1c d\u1ea1ng vi khu\u1ea9n \u0111\u1ea1i di\u1ec7n cho c\u00e1c h\u00ecnh th\u1ee9c \u1edf b\u1ec7nh vi\u1ec7n v\u00e0 \u1edf c\u1ed9ng \u0111\u1ed3ng c\u1ee7a t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p ba lo\u1ea1i kh\u00e1ng sinh \u0111\u1ec3 ch\u1eefa cho nhi\u1ec1u d\u1ea1ng vi khu\u1ea9n MRSA kh\u00e1c nhau v\u00e0 t\u00ecm ra r\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa b\u1ec7nh n\u00e0y c\u00f3 hi\u1ec7u qu\u1ea3 trong m\u1ecdi tr\u01b0\u1eddng h\u1ee3p<\/p>\n

Sau \u0111\u00f3, trong c\u00e1c th\u00ed nghi\u1ec7m \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh b\u1edfi c\u00e1c c\u1ed9ng s\u1ef1 t\u1ea1i \u0110\u1ea1i h\u1ecdc Notre Dame, nh\u00f3m nghi\u00ean c\u1ee9u ph\u00e1t hi\u1ec7n ra r\u1eb1ng thu\u1ed1c k\u1ebft h\u1ee3p \u0111\u00e3 ch\u1eefa h\u1ebft cho nh\u1eefng con chu\u1ed9t nhi\u1ec5m MRSA v\u1edbi hi\u1ec7u l\u1ef1c t\u01b0\u01a1ng t\u1ef1 nh\u01b0 m\u1ed9t trong nh\u1eefng lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh m\u1ea1nh nh\u1ea5t tr\u00ean th\u1ecb tr\u01b0\u1eddng.<\/p>\n

“N\u1ebfu kh\u00f4ng \u0111i\u1ec1u tr\u1ecb, nh\u1eefng con chu\u1ed9t nhi\u1ec5m MRSA ch\u1ec9 c\u00f3 th\u1ec3 s\u1ed1ng kh\u00f4ng qu\u00e1 m\u1ed9t ng\u00e0y, nh\u01b0ng s\u1ef1 k\u1ebft h\u1ee3p ba lo\u1ea1i thu\u1ed1c \u0111\u00e3 ch\u1eefa kh\u1ecfi cho ch\u00fang” Dantas n\u00f3i. “Sau khi \u0111i\u1ec1u tr\u1ecb, nh\u1eefng con chu\u1ed9t \u0111\u00e3 h\u1ed3i ph\u1ee5c nhanh ch\u00f3ng”.<\/p>\n

Dantas gi\u1ea3i th\u00edch r\u1eb1ng c\u00e1c lo\u1ea1i thu\u1ed1c \u0111\u00e3 t\u1ea5n c\u00f4ng v\u00e0o c\u00e1c th\u00e0nh t\u1ebf b\u00e0o c\u1ee7a vi khu\u1ea9n theo c\u01a1 ch\u1ebf b\u1ed5 tr\u1ee3, ngh\u0129a l\u00e0 khi k\u1ebft h\u1ee3p n\u00f3 s\u1ebd c\u00f3 hi\u1ec7u qu\u1ea3 h\u01a1n khi s\u1eed d\u1ee5ng \u0111\u01a1n l\u1ebb.<\/p>\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng ph\u00e1t hi\u1ec7n ra nh\u1eefng lo\u1ea1i thu\u1ed1c \u0111\u00e3 kh\u00f4ng t\u1ea1o ra t\u00ednh kh\u00e1ng thu\u1ed1c c\u1ee7a vi khu\u1ea9n MRSA. \u0110\u00e2y l\u00e0 m\u1ed9t ph\u00e1t hi\u1ec7n quan tr\u1ecdng v\u00ec ng\u00e0y c\u00e0ng nhi\u1ec1u vi khu\u1ea9n \u0111ang kh\u00e1ng thu\u1ed1c.<\/p>\n

\u201cS\u1ef1 k\u1ebft h\u1ee3p ba lo\u1ea1i thu\u1ed1c n\u00e0y gi\u00fap ng\u0103n ch\u1eb7n MRSA tr\u1edf n\u00ean \u0111\u1ec1 kh\u00e1ng ” Dantas n\u00f3i. “Ch\u00fang t\u00f4i bi\u1ebft t\u1ea5t c\u1ea3 c\u00e1c vi khu\u1ea9n \u0111\u1ec1u ph\u00e1t tri\u1ec3n kh\u1ea3 n\u0103ng \u0111\u1ec1 kh\u00e1ng v\u1edbi thu\u1ed1c kh\u00e1ng sinh, nh\u01b0ng s\u1ef1 k\u1ebft h\u1ee3p b\u1ed9 ba n\u00e0y c\u00f3 th\u1ec3 gi\u00fap k\u00e9o d\u00e0i m\u1ed9t kho\u1ea3ng th\u1eddi gian \u0111\u00e1ng k\u1ec3\u201d.<\/p>\n

Nh\u00f3m c\u1ee7a Dantas c\u0169ng \u0111ang \u0111i\u1ec1u tra c\u00e1c thu\u1ed1c kh\u00e1ng sinh kh\u00e1c – \u0111\u00e3 v\u00f4 hi\u1ec7u tr\u01b0\u1edbc nhi\u1ec1u vi khu\u1ea9n g\u00e2y b\u1ec7nh – \u0111\u1ec3 xem n\u1ebfu n\u00f3 c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng khi s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n

“Ch\u00fang t\u00f4i b\u1eaft \u0111\u1ea7u v\u1edbi MRSA b\u1edfi v\u00ec n\u00f3 l\u00e0 m\u1ed9t vi khu\u1ea9n r\u1ea5t kh\u00f3 ti\u00eau di\u1ec7t,” \u00f4ng n\u00f3i. “Nh\u01b0ng ch\u00fang t\u00f4i r\u1ea5t l\u1ea1c quan v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p t\u01b0\u01a1ng t\u1ef1 c\u00f3 th\u1ec3 ch\u1ed1ng l\u1ea1i t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh ch\u1ebft ng\u01b0\u1eddi kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 Pseudomonas v\u00e0 m\u1ed9t s\u1ed1 d\u1ea1ng \u0111\u1ed9c kh\u00e1c c\u1ee7a E. coli.”<\/p>\n

Theo sciencedaily<\/strong><\/p>\n

Kim T\u01b0\u01a1i<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Theo m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi, ba lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh n\u00e0y (n\u1ebfu s\u1eed d\u1ee5ng ri\u00eang l\u1ebb s\u1ebd kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i nhi\u1ec5m t\u1ee5 c\u1ea7u khu\u1ea9n kh\u00e1ng thu\u1ed1c) c\u00f3 th\u1ec3 gi\u1ebft ch\u1ebft c\u00e1c m\u1ea7m b\u1ec7nh ch\u1ebft ng\u01b0\u1eddi khi k\u1ebft h\u1ee3p c\u00f9ng nhau. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y Washington, St. Louis […]<\/p>\n","protected":false},"author":17,"featured_media":4384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-4172","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4172","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=4172"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4172\/revisions"}],"predecessor-version":[{"id":4385,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/4172\/revisions\/4385"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/4384"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=4172"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=4172"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=4172"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}