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<\/p>\n\n\n\nC\u00e1c chuy\u00ean gia t\u1eeb \u0110\u1ea1i h\u1ecdc Y khoa Nam Carolina (MUSC) \u0111\u00e3 ph\u00e1t hi\u1ec7n th\u1ee9c \u0103n nhanh, \u0111\u1ed3 \u0103n v\u1eb7t c\u00f3 n\u1ed3ng \u0111\u1ed9 glycat h\u00f3a b\u1ec1n v\u1eefng (AGEs) cao l\u00e0m t\u0103ng t\u1ef7 l\u1ec7 m\u1eafc ung th\u01b0 v\u00fa \u1edf ng\u01b0\u1eddi tr\u1ebb tu\u1ed5i.<\/p>\n\n\n\n
Theo TS.BS d\u1ecbch t\u1ec5 h\u1ecdc Tomotaka Ugai, Tr\u01b0\u1eddng Y Harvard – ng\u01b0\u1eddi c\u00f3 nghi\u00ean c\u1ee9u t\u1eadp trung v\u00e0o b\u1ec7nh kh\u1edfi ph\u00e1t s\u1edbm – nh\u1eadn \u0111\u1ecbnh m\u1ed9t ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng kh\u00f4ng l\u00e0nh m\u1ea1nh c\u00f3 th\u1ec3 g\u00e2y vi\u00eam h\u1ec7 th\u1ed1ng v\u00e0 kh\u00e1ng insulin, \u0111\u1ed3ng th\u1eddi d\u1ec5 l\u00e0m thay \u0111\u1ed5i h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t, do \u0111\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng.\u00a0Th\u1ee9c \u0103n nhanh \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t ph\u1ea7n ch\u00ednh trong ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng \u1edf nhi\u1ec1u qu\u1ed1c gia \u0111\u01b0\u1ee3c cho l\u00e0 l\u00e0m gia t\u0103ng c\u00e1c b\u1ec7nh kh\u00f4ng l\u00e2y nhi\u1ec5m bao g\u1ed3m c\u1ea3 ung th\u01b0. Nhi\u1ec1u b\u1eb1ng ch\u1ee9ng cho th\u1ea5y m\u1ed1i li\u00ean quan \u0111\u00e1ng k\u1ec3 nh\u1ea5t qu\u00e1n gi\u1eefa vi\u1ec7c h\u1ea5p th\u1ee5 th\u1ee9c \u0103n nhanh v\u00e0 nguy c\u01a1 m\u1eafc b\u1ec7nh ung th\u01b0 n\u00f3i chung v\u00e0 m\u1ed9t s\u1ed1 b\u1ec7nh ung th\u01b0 c\u1ee5 th\u1ec3 nh\u01b0 ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, ung th\u01b0 v\u00fa, ung th\u01b0 tuy\u1ebfn t\u1ee5y.<\/p>\n\n\n\n
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M\u1ed9t c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u m\u1edbi \u0111\u00e2y \u0111\u01b0\u1ee3c \u0111\u0103ng tr\u00ean t\u1ea1p ch\u00ed Breast Cancer Research v\u00e0o th\u00e1ng 10, c\u00e1c chuy\u00ean gia t\u1eeb \u0110\u1ea1i h\u1ecdc Y khoa Nam Carolina (MUSC) \u0111\u00e3 ph\u00e1t hi\u1ec7n th\u1ee9c \u0103n nhanh, \u0111\u1ed3 \u0103n v\u1eb7t c\u00f3 n\u1ed3ng \u0111\u1ed9 glycat h\u00f3a b\u1ec1n v\u1eefng (AGEs) cao l\u00e0m t\u0103ng t\u1ef7 l\u1ec7 m\u1eafc ung th\u01b0 v\u00fa. AGEs – S\u1ea3n ph\u1ea9m glycat h\u00f3a b\u1ec1n v\u1eefng (advanced glycation end products) l\u00e0 c\u00e1c protein ho\u1eb7c ch\u1ea5t b\u00e9o b\u1ecb glycat h\u00f3a sau khi ti\u1ebfp x\u00fac v\u1edbi c\u00e1c \u0111\u01b0\u1eddng. Ch\u00fang l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y ra nh\u1eefng t\u1ed5n h\u1ea1i cho h\u1ec7 th\u1ea7n kinh, c\u00e1c b\u1ec7nh v\u1ec1 m\u1eaft, th\u1eadn v\u00e0 tim \u1edf ng\u01b0\u1eddi b\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 c\u0169ng l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y ra nhi\u1ec1u \u1ea3nh h\u01b0\u1edfng ti\u00eau c\u1ef1c c\u1ee7a qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a nhanh \u1edf nhi\u1ec1u ng\u01b0\u1eddi. C\u00e1c t\u00e1c gi\u1ea3 cho bi\u1ebft m\u1ee9c AGEs t\u0103ng c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 v\u00fa. Tuy nhi\u00ean, ch\u00fang g\u1ea7n nh\u01b0 b\u1ecb b\u1ecf qua do thi\u1ebfu nghi\u00ean c\u1ee9u v\u1ec1 m\u1ed1i li\u00ean h\u1ec7 nh\u00e2n qu\u1ea3 tr\u1ef1c ti\u1ebfp.<\/p>\n\n\n\n
\u0110\u1ec3 \u0111i \u0111\u1ebfn k\u1ebft lu\u1eadn n\u00e0y, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 n\u1ea5u th\u1ee9c \u0103n g\u1ed1c glucose \u1edf nhi\u1ec7t \u0111\u1ed9 120 \u0111\u1ed9 C trong 15 ph\u00fat, t\u1ea1o ra c\u00e1c s\u1ea3n ph\u1ea9m c\u00f3 ph\u1ed5 AGEs th\u01b0\u1eddng th\u1ea5y trong th\u1ef1c ph\u1ea9m chi\u00ean, n\u01b0\u1edbng. Sau \u0111\u00f3, h\u1ecd chia chu\u1ed9t th\u00ed nghi\u1ec7m th\u00e0nh ba nh\u00f3m: nh\u00f3m \u0111\u1ed1i ch\u1ee9ng v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n chu\u1ed9t th\u00f4ng th\u01b0\u1eddng, nh\u00f3m \u0103n th\u1ef1c ph\u1ea9m c\u00f3 AGEs n\u1ed3ng \u0111\u1ed9 th\u1ea5p v\u00e0 nh\u00f3m \u0103n th\u1ef1c ph\u1ea9m c\u00f3 AGEs n\u1ed3ng \u0111\u1ed9 cao. C\u00e1c chuy\u00ean gia ph\u00e1t hi\u1ec7n c\u00e1c con chu\u1ed9t \u0103n th\u1ef1c ph\u1ea9m ch\u1ee9a nhi\u1ec1u ch\u1ea5t b\u00e9o b\u1ecb glycat h\u00f3a t\u1ea1o ra t\u1ebf b\u00e0o v\u00fa b\u1ea5t th\u01b0\u1eddng, c\u00f3 s\u1ef1 thay \u0111\u1ed5i \u1edf m\u00f4 v\u00fa t\u01b0\u01a1ng t\u1ef1 c\u00e1c b\u1ec7nh nh\u00e2n ung th\u01b0 giai \u0111o\u1ea1n \u0111\u1ea7u. S\u1ef1 thay \u0111\u1ed5i n\u00e0y \u1edf ng\u01b0\u1eddi \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u00ecnh tr\u1ea1ng “gia t\u0103ng m\u1eadt \u0111\u1ed9 v\u00fa”, th\u1ec3 hi\u1ec7n \u1edf \u1ea3nh ch\u1ee5p quang tuy\u1ebfn v\u00fa.<\/p>\n\n\n\n
Ph\u00e1t hi\u1ec7n n\u00e0y kh\u00f4ng cho th\u1ea5y m\u1ed1i li\u00ean h\u1ec7 nh\u00e2n qu\u1ea3 tr\u1ef1c ti\u1ebfp gi\u1eefa th\u1ef1c ph\u1ea9m c\u00f3 n\u1ed3ng \u0111\u1ed9 AGEs cao v\u00e0 ung th\u01b0 ph\u00fa. Tuy nhi\u00ean, n\u00f3 ch\u1ec9 ra r\u1eb1ng vi\u1ec7c ti\u00eau th\u1ee5 \u0111\u1ed3 \u0103n ch\u1ebf bi\u1ebfn s\u1eb5n l\u00e0m t\u0103ng nguy c\u01a1 t\u1ea1o t\u1ebf b\u00e0o v\u00fa b\u1ea5t th\u01b0\u1eddng, d\u1eabn \u0111\u1ebfn ung th\u01b0 v\u00fa trong t\u01b0\u01a1ng lai. Theo ti\u1ebfn s\u0129 Steven Quay, gi\u00e1m s\u00e1t vi\u00ean nghi\u00ean c\u1ee9u, l\u0129nh v\u1ef1c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa \u0111\u00e3 c\u00f3 nhi\u1ec1u ti\u1ebfn b\u1ed9 v\u00e0 th\u00e0nh c\u00f4ng, song vi\u1ec7c ng\u0103n ng\u1eeba v\u1eabn r\u1ea5t c\u1ea7n thi\u1ebft. \u00d4ng gi\u1ea3i th\u00edch s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a v\u00fa \u1edf tu\u1ed5i d\u1eady khi\u1ebfn c\u01a1 th\u1ec3 d\u1ec5 t\u1ed5n th\u01b0\u01a1ng trong v\u00e0i n\u0103m. C\u00e1c t\u00e1c \u0111\u1ed9ng t\u1eeb m\u00f4i tr\u01b0\u1eddng, ch\u1ebf \u0111\u1ed9 \u0103n ho\u1eb7c nh\u1eefng th\u1ee7 t\u1ee5c y khoa nh\u01b0 ch\u1ee5p X-quang c\u00f3 th\u1ec3 \u0111\u1ec3 l\u1ea1i h\u1eadu qu\u1ea3 h\u01a1n.<\/p>\n\n\n\n