{"id":29442,"date":"2021-10-28T14:10:00","date_gmt":"2021-10-28T07:10:00","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=29442"},"modified":"2022-02-15T09:33:51","modified_gmt":"2022-02-15T02:33:51","slug":"lan-dau-tien-than-heo-duoc-ghep-thanh-cong-ghep-cho-nguoi","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/lan-dau-tien-than-heo-duoc-ghep-thanh-cong-ghep-cho-nguoi\/","title":{"rendered":"L\u1ea7n \u0111\u1ea7u ti\u00ean, th\u1eadn heo \u0111\u01b0\u1ee3c gh\u00e9p th\u00e0nh c\u00f4ng gh\u00e9p cho ng\u01b0\u1eddi"},"content":{"rendered":"\n
\"L\u1ea7n<\/figure>\n\n\n\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u1edf M\u1ef9 \u0111\u00e3 th\u00e0nh c\u00f4ng gh\u00e9p th\u1eadn c\u1ee7a heo bi\u1ebfn \u0111\u1ed5i gene<\/a> cho ng\u01b0\u1eddi, m\u1ed9t b\u01b0\u1edbc l\u1edbn trong \u01b0\u1edbc m\u01a1 su\u1ed1t h\u00e0ng th\u1eadp k\u1ef7 s\u1eed d\u1ee5ng n\u1ed9i t\u1ea1ng \u0111\u1ed9ng v\u1eadt<\/a> c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n c\u1ee7a con ng\u01b0\u1eddi. L\u1ee3n v\u1ed1n l\u00e0 \u0111\u1ed9ng v\u1eadt tr\u1ecdng t\u00e2m trong c\u00e1c cu\u1ed9c nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y \u0111\u1ec3 gi\u1ea3i quy\u1ebft t\u00ecnh tr\u1ea1ng thi\u1ebfu n\u1ed9i t\u1ea1ng c\u1ee7a con ng\u01b0\u1eddi. Th\u1ebf nh\u01b0ng, m\u1ed9t lo\u1ea1i ph\u00e2n t\u1eed \u0111\u01b0\u1eddng trong t\u1ebf b\u00e0o c\u1ee7a ch\u00fang l\u1ea1i g\u00e2y ra s\u1ef1 ph\u1ea3n \u1ee9ng th\u1ea3i ngay l\u1eadp t\u1ee9c. Tuy nhi\u00ean, qu\u1ea3 th\u1eadn trong cu\u1ed9c ph\u1eabu thu\u1eadt<\/a> l\u1ea7n n\u00e0y \u0111\u1ebfn t\u1eeb m\u1ed9t con l\u1ee3n \u0111\u00e3 qua ch\u1ec9nh s\u1eeda gene \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 alpha-gal, \u0111\u00e3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf lo\u1ea1i \u0111\u01b0\u1eddng \u0111\u00f3 v\u00e0 tr\u00e1nh \u0111\u01b0\u1ee3c s\u1ef1 t\u1ea5n c\u00f4ng c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/p>\n\n\n\n

\"than-heo-4.jpg\"<\/p>\n\n\n\n

C\u00e1c b\u00e1c s\u0129 \u0111\u00e3 g\u1eafn qu\u1ea3 th\u1eadn v\u00e0o c\u00e1c m\u1ea1ch m\u00e1u b\u00ean ngo\u00e0i c\u01a1 th\u1ec3 c\u1ee7a b\u1ec7nh nh\u00e2n \u0111\u00e3 ch\u1ebft n\u00e3o, c\u00f3 d\u1ea5u hi\u1ec7u r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 quan s\u00e1t n\u00f3 trong v\u00f2ng 2 ng\u00e0y. K\u1ebft qu\u1ea3, th\u1eadn \u0111\u00e3 ho\u1ea1t \u0111\u1ed9ng nh\u1eefng g\u00ec n\u00f3 c\u1ea7n ph\u1ea3i l\u00e0m, l\u1ecdc ch\u1ea5t th\u1ea3i v\u00e0 s\u1ea3n xu\u1ea5t n\u01b0\u1edbc ti\u1ec3u, quan tr\u1ecdng h\u01a1n l\u00e0 kh\u00f4ng g\u00e2y ra ph\u1ea3n \u1ee9ng \u0111\u00e0o th\u1ea3i.<\/p>\n\n\n\n

Ti\u1ebfn s\u0129 Robert Montgomery, ng\u01b0\u1eddi d\u1eabn \u0111\u1ea7u nh\u00f3m ph\u1eabu thu\u1eadt t\u1ea1i NYU Langone Health cho bi\u1ebft: \u201cTh\u1eadn c\u00f3 ch\u1ee9c n\u0103ng ho\u00e0n to\u00e0n b\u00ecnh th\u01b0\u1eddng, kh\u00f4ng g\u00e2y ra ph\u1ea3n \u1ee9ng \u0111\u00e0o th\u1ea3i m\u00e0 ch\u00fang t\u00f4i lo l\u1eafng. Nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 b\u01b0\u1edbc ti\u1ebfn quan tr\u1ecdng, v\u00e0 cho th\u1ea5y ch\u00fang ta \u0111ang \u0111i \u0111\u00fang h\u01b0\u1edbng.” Th\u01b0\u1eddng s\u1ef1 \u0111\u00e0o th\u1ea3i m\u1ea1nh m\u1ebd s\u1ebd x\u1ea3y ra d\u01b0\u1eddng nh\u01b0 ngay l\u1eadp t\u1ee9c n\u1ebfu th\u1eadn l\u1ee3n ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebfn \u0111\u1ed5i c\u1ea5y gh\u00e9p v\u00e0o \u0111\u1ed9ng v\u1eadt linh tr\u01b0\u1edfng.<\/p>\n\n\n\n

\"baby-fae.jpg\"<\/p>\n\n\n\n

Gi\u1ea5c m\u01a1 c\u1ea5y gh\u00e9p n\u1ed9i t\u1ea1ng \u0111\u1ed9ng v\u1eadt sang ng\u01b0\u1eddi \u0111\u00e3 c\u00f3 t\u1eeb th\u1ebf k\u1ef7 17 v\u00e0 c\u00f3 c\u1ea3 m\u1ed9t thu\u1eadt ng\u1eef \u0111\u1ec3 d\u00e0nh ri\u00eang cho vi\u1ec7c gh\u00e9p t\u1ea1ng ho\u1eb7c m\u00f4 t\u1eeb lo\u00e0i n\u00e0y sang lo\u00e0i kh\u00e1c l\u00e0 xenotransplantation<\/a>. V\u00e0o th\u1ebf k\u1ef7 20, c\u00e1c b\u00e1c s\u0129 \u0111\u00e3 c\u1ed1 g\u1eafng gh\u00e9p n\u1ed9i t\u1ea1ng t\u1eeb kh\u1ec9 \u0111\u1ea7u ch\u00f3 v\u00e0 ng\u01b0\u1eddi. \u0110\u00e2y \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t trong nh\u1eefng ca ph\u1eabu thu\u1eadt \u0111\u1eb7c bi\u1ec7t nh\u1ea5t c\u1ee7a gi\u1edbi y khoa: gh\u00e9p tim c\u1ee7a m\u1ed9t con kh\u1ec9 \u0111\u1ea7u ch\u00f3 v\u00e0o m\u1ed9t \u0111\u1ee9a tr\u1ebb s\u01a1 sinh s\u1eafp ch\u1ebft. Cu\u1ed1i c\u00f9ng, \u0111\u1ee9a tr\u1ebb \u0111\u00e3 s\u1ed1ng \u0111\u01b0\u1ee3c 21 ng\u00e0y sau ca ph\u1eabu thu\u1eadt.<\/p>\n\n\n\n

\"than-heo-8.jpg\"<\/p>\n\n\n\n

Do kh\u00f4ng c\u00f3 s\u1ef1 th\u00e0nh c\u00f4ng l\u00e2u d\u00e0i v\u00e0 c\u1ea3 s\u1ef1 tranh c\u00e3i, \u1ed3n \u00e0o t\u1eeb d\u01b0 lu\u1eadn m\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 chuy\u1ec3n t\u1eeb \u0111\u1ed9ng v\u1eadt linh tr\u01b0\u1edfng sang l\u1ee3n. B\u1edfi l\u1ee3n c\u00f3 l\u1ee3i th\u1ebf h\u01a1n kh\u1ec9 v\u00e0 v\u01b0\u1ee3n, ch\u00fang \u0111\u01b0\u1ee3c nu\u00f4i \u0111\u1ec3 cung c\u1ea5p th\u1ef1c ph\u1ea9m, v\u00ec th\u1ebf vi\u1ec7c d\u00f9ng c\u01a1 quan n\u1ed9i t\u1ea1ng c\u1ee7a ch\u00fang g\u00e2y \u00edt s\u1ef1 tranh c\u00e3i v\u1ec1 \u0111\u1ea1o \u0111\u1ee9c h\u01a1n. B\u00ean c\u1ea1nh \u0111\u00f3, l\u1ee3n c\u00f3 l\u1ee9a \u0111\u1ebb kh\u00e1 l\u1edbn, th\u1eddi gian mang thai ng\u1eafn v\u00e0 k\u00edch c\u1ee1 n\u1ed9i t\u1ea1ng c\u0169ng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi ng\u01b0\u1eddi.<\/p>\n\n\n\n

\"than-heo-3.jpg\"<\/p>\n\n\n\n

Van tim l\u1ee3n c\u0169ng \u0111\u00e3 t\u1eebng \u0111\u01b0\u1ee3c d\u00f9ng trong nhi\u1ec1u th\u1eadp k\u1ef7 \u1edf ng\u01b0\u1eddi, hay da l\u1ee3n c\u0169ng t\u1eebng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 gh\u00e9p v\u00e0o c\u01a1 th\u1ec3 ng\u01b0\u1eddi cho c\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u1ecfng n\u1eb7ng. Trong tr\u01b0\u1eddng h\u1ee3p c\u1ee7a c\u00e1c b\u00e1c s\u0129 NYU, ph\u1eabu thu\u1eadt di\u1ec5n ra v\u1edbi thi th\u1ec3 c\u1ee7a m\u1ed9t b\u1ec7nh nh\u00e2n n\u1eef \u0111\u00e3 qua \u0111\u1eddi sau khi nh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 \u0111\u1ed3ng \u00fd t\u1eeb gia \u0111\u00ecnh c\u00f4. Tr\u01b0\u1edbc khi qua \u0111\u1eddi, b\u1ec7nh nh\u00e2n n\u00e0y \u0111\u00e3 mong mu\u1ed1n \u0111\u01b0\u1ee3c hi\u1ebfn t\u1eb7ng n\u1ed9i t\u1ea1ng c\u1ee7a m\u00ecnh. Gia \u0111\u00ecnh c\u00f4 c\u1ea3m th\u1ea5y c\u00f3 th\u1ec3 \u201cm\u1ed9t s\u1ed1 \u0111i\u1ec1u t\u1ed1t \u0111\u1eb9p s\u1ebd di\u1ec5n ra t\u1eeb ch\u00ednh c\u01a1 th\u1ec3 c\u1ee7a c\u00f4\u201d. Th\u1eadt v\u1eady, h\u01a1n 90,000 ng\u01b0\u1eddi \u1edf M\u1ef9 \u0111ang ch\u1edd \u0111\u01b0\u1ee3c gh\u00e9p th\u1eadn t\u1ea1i M\u1ef9 v\u00e0 m\u1ed7i ng\u00e0y, c\u00f3 \u0111\u1ebfn 12 ng\u01b0\u1eddi ch\u1ebft \u0111i v\u00ec kh\u00f4ng th\u1ec3 ch\u1edd \u0111\u01b0\u1ee3c.<\/p>\n\n\n\n

L\u1ee3n bi\u1ebfn \u0111\u1ed5i gene \u0111\u01b0\u1ee3c nu\u00f4i b\u1edfi Revivicor, m\u1ed9t c\u00f4ng ty con c\u1ee7a United Therapeutics. Lo\u00e0i l\u1ee3n bi\u1ebfn \u0111\u1ed5i \u0111\u00e3 \u0111\u01b0\u1ee3c C\u1ee5 qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m M\u1ef9 (FDA<\/a>) ph\u00ea duy\u1ec7t v\u00e0o th\u00e1ng 12\/2020 l\u00e0 an to\u00e0n \u0111\u1ec3 l\u00e0m th\u1ef1c ph\u1ea9m v\u00e0 thu\u1ed1c cho con ng\u01b0\u1eddi. Tuy nhi\u00ean, FDA cho bi\u1ebft vi\u1ec7c gh\u00e9p n\u1ed9i t\u1ea1ng l\u1ee3n v\u00e0o c\u01a1 th\u1ec3 ng\u01b0\u1eddi s\u1ed1ng v\u1eabn ch\u01b0a c\u00f2n c\u1ea7n th\u00eam nhi\u1ec1u gi\u1ea5y t\u1edd \u0111\u1ec3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn.<\/p>\n\n\n\n

Rubi Lee <\/strong><\/p>\n\n\n\n

https:\/\/tinhte.vn\/thread\/lan-dau-tien-than-heo-duoc-ghep-thanh-cong-ghep-cho-nguoi.3421311\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u1edf M\u1ef9 \u0111\u00e3 th\u00e0nh c\u00f4ng gh\u00e9p th\u1eadn c\u1ee7a heo bi\u1ebfn \u0111\u1ed5i gene cho ng\u01b0\u1eddi, m\u1ed9t b\u01b0\u1edbc l\u1edbn trong \u01b0\u1edbc m\u01a1 su\u1ed1t h\u00e0ng th\u1eadp k\u1ef7 s\u1eed d\u1ee5ng n\u1ed9i t\u1ea1ng \u0111\u1ed9ng v\u1eadt c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n c\u1ee7a con ng\u01b0\u1eddi. L\u1ee3n v\u1ed1n l\u00e0 \u0111\u1ed9ng v\u1eadt tr\u1ecdng t\u00e2m trong c\u00e1c cu\u1ed9c nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y \u0111\u1ec3 gi\u1ea3i quy\u1ebft t\u00ecnh […]<\/p>\n","protected":false},"author":23,"featured_media":29443,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-29442","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/29442","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=29442"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/29442\/revisions"}],"predecessor-version":[{"id":31088,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/29442\/revisions\/31088"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/29443"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=29442"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=29442"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=29442"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}