{"id":27593,"date":"2020-04-25T16:36:00","date_gmt":"2020-04-25T09:36:00","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=27593"},"modified":"2021-11-09T09:48:35","modified_gmt":"2021-11-09T02:48:35","slug":"hop-chat-tim-thay-trong-loai-bot-bien-co-the-chua-ung-thu","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/hop-chat-tim-thay-trong-loai-bot-bien-co-the-chua-ung-thu\/","title":{"rendered":"H\u1ee2P CH\u1ea4T T\u00ccM TH\u1ea4Y TRONG LO\u00c0I B\u1eccT BI\u1ec2N C\u00d3 TH\u1ec2 CH\u1eeeA UNG TH\u01af"},"content":{"rendered":"\n

M\u1ed9t ph\u00e2n t\u1eed c\u00f3 t\u00ean l\u00e0 manzamine A trong lo\u00e0i b\u1ecdt bi\u1ec3n \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y \u1edf V\u1ecbnh Manado, In\u0111\u00f4n\u00eaxia, cho th\u1ea5y kh\u1ea3 n\u0103ng ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 c\u1ed5 t\u1eed cung. C\u00e1c k\u1ebft qu\u1ea3 c\u1ee7a c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u h\u1ee3p t\u00e1c gi\u1eefa Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y South Carolina (MUSC) v\u1edbi c\u00e1c sinh vi\u00ean v\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc South Carolina (UofSC), \u0110\u1ea1i h\u1ecdc Charleston, \u0110\u1ea1i h\u1ecdc Gadjah Mad t\u1ea1i Indonesia v\u00e0 \u0110\u1ea1i h\u1ecdc Malaya t\u1ea1i Malaixia \u0111\u00e3 \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Journal of Natural Products<\/em> m\u1edbi \u0111\u00e2y.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

Ti\u1ebfn s\u0129 khoa h\u1ecdc d\u01b0\u1ee3c Mark Hamann, Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y  South Carolina, chuy\u00ean nghi\u00ean c\u1ee9u c\u00e1c ti\u1ec1m n\u0103ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a c\u00e1c s\u1ea3n ph\u1ea9m t\u1ef1 nhi\u00ean. Ngu\u1ed3n: Sarah Pack, \u0110\u1ea1i h\u1ecdc Y South Carolina.<\/em><\/p>\n\n\n\n

Hi\u1ec7p h\u1ed9i Ung th\u01b0 Hoa K\u1ef3 \u01b0\u1edbc t\u00ednh s\u1ebd c\u00f3 kho\u1ea3ng 13.800 ca \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1edbi m\u1eafc b\u1ec7nh ung th\u01b0 c\u1ed5 t\u1eed cung v\u00e0 kho\u1ea3ng 4.290 tr\u01b0\u1eddng h\u1ee3p s\u1ebd b\u1ecb t\u1eed vong v\u00e0o n\u0103m 2020. M\u1eb7c d\u00f9 c\u00e1c x\u00e9t nghi\u1ec7m Pap v\u00e0 ti\u00eam ph\u00f2ng v\u1eafc-xin HPV \u0111\u00e3 gi\u00fap gi\u1ea3m s\u1ed1 ca t\u1eed vong do ung th\u01b0 c\u1ed5 t\u1eed cung, nh\u01b0ng b\u1ec7nh ung th\u01b0 c\u1ed5 t\u1eed cung v\u1eabn l\u00e0 c\u0103n b\u1ec7nh ung th\u01b0 ph\u1ed5 bi\u1ebfn th\u1ee9 t\u01b0 \u1edf ph\u1ee5 n\u1eef.<\/p>\n\n\n\n

Nghi\u00ean c\u1ee9u MUSC-UofSC \u0111\u00e3 th\u1ef1c hi\u1ec7n ki\u1ec3m tra t\u00e1c d\u1ee5ng ch\u1ed1ng t\u0103ng tr\u01b0\u1edfng v\u00e0 ti\u00eau di\u1ec7t t\u1ebf b\u00e0o ung th\u01b0 c\u1ee7a manzamine A trong b\u1ed1n d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0 c\u1ed5 t\u1eed cung kh\u00e1c nhau. K\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c cho th\u1ea5y, Manzamine A \u0111\u00e3 ng\u0103n ch\u1eb7n c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 c\u1ed5 t\u1eed cung ph\u00e1t tri\u1ec3n v\u00e0 khi\u1ebfn m\u1ed9t s\u1ed1 t\u1ebf b\u00e0o ch\u1ebft nh\u01b0ng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng, kh\u00f4ng g\u00e2y ung th\u01b0.<\/p>\n\n\n\n

Mark T. Hamann, ti\u1ebfn s\u0129 d\u01b0\u1ee3c h\u1ecdc Khoa kh\u00e1m ph\u00e1 thu\u1ed1c v\u00e0 khoa h\u1ecdc y sinh t\u1ea1i MUSC, \u0111\u1ed3ng t\u00e1c gi\u1ea3 b\u00e0i b\u00e1o cho bi\u1ebft: \u201c\u0110\u00e2y l\u00e0 m\u1ed9t \u1ee9ng d\u1ee5ng m\u1edbi, r\u1ea5t th\u00fa v\u1ecb \u0111\u1ed1i v\u1edbi m\u1ed9t lo\u1ea1i ph\u00e2n t\u1eed m\u00e0 tr\u01b0\u1edbc \u0111\u00e2y n\u00f3 \u0111\u00e3 cho th\u1ea5y c\u00f3 ti\u1ec1m n\u0103ng l\u1edbn trong vi\u1ec7c ki\u1ec3m so\u00e1t b\u1ec7nh s\u1ed1t r\u00e9t v\u00e0 c\u00f3 \u0111\u1eb7c t\u00ednh gi\u1ed1ng nh\u01b0 thu\u1ed1c<\/em>\u201d.<\/p>\n\n\n\n

\u201cC\u00e1c s\u1ea3n ph\u1ea9m t\u1ef1 nhi\u00ean \u0111\u00e3 \u0111\u01b0a \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a h\u1ea7u h\u1ebft c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh, li\u1ec7u ph\u00e1p ch\u1ed1ng ung th\u01b0 v\u00e0 nhi\u1ec1u bi\u1ec7n ph\u00e1p ki\u1ec3m so\u00e1t c\u01a1n \u0111au<\/em>\u201d, Hamann gi\u1ea3i th\u00edch.<\/p>\n\n\n\n

M\u1ed9t \u0111\u1ed3ng t\u00e1c gi\u1ea3 kh\u00e1c c\u1ee7a nghi\u00ean c\u1ee9u l\u00e0 ti\u1ebfn s\u1ef9 Dev Karan, c\u1ef1u ph\u00f3 gi\u00e1o s\u01b0 t\u1ea1i UofSC, hi\u1ec7n \u0111ang c\u00f4ng t\u00e1c t\u1ea1i Khoa b\u1ec7nh l\u00fd h\u1ecdc, Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y, Wisconsin.<\/p>\n\n\n\n

Trong c\u00e1c nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00f3, nh\u00f3m c\u1ee7a Hamann \u0111\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c c\u00e1c h\u1ee3p ch\u1ea5t c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb b\u1ecdt bi\u1ec3n c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i kh\u1ed1i u \u00e1c t\u00ednh c\u0169ng nh\u01b0 ung th\u01b0 tuy\u1ebfn ti\u1ec1n li\u1ec7t v\u00e0 tuy\u1ebfn t\u1ee5y. Manzamine A c\u0169ng c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i k\u00fd sinh tr\u00f9ng g\u00e2y ra b\u1ec7nh s\u1ed1t r\u00e9t. M\u1ed9t s\u1ed1 ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 c\u1ee7a nh\u00f3m thu\u1ed1c \u0111\u1ed9c \u0111\u00e1o n\u00e0y hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c xem l\u00e0 \u201c\u1ee9ng c\u1eed vi\u00ean\u201d \u0111\u1ec3 ki\u1ec3m so\u00e1t COVID-19, c\u0103n b\u1ec7nh do coronavirus m\u1edbi g\u00e2y ra.<\/p>\n\n\n\n

Trong b\u00e1o c\u00e1o hi\u1ec7n t\u1ea1i, manzamine A l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u1ed9 bi\u1ec3u hi\u1ec7n c\u1ee7a m\u1ed9t protein \u0111\u01b0\u1ee3c bi\u1ebft l\u00e0 c\u00f3 bi\u1ec3u hi\u1ec7n cao \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh ung th\u01b0, bao g\u1ed3m ung th\u01b0 c\u1ed5 t\u1eed cung v\u00e0 khi\u1ebfn t\u00ecnh tr\u1ea1ng b\u1ec7nh x\u1ea5u h\u01a1n.<\/p>\n\n\n\n

C\u00e1c m\u00f4 h\u00ecnh m\u00e1y t\u00ednh cho th\u1ea5y manzamine A \u201ct\u00e1c \u0111\u1ed9ng<\/em>\u201d t\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf protein \u0111\u00e3 t\u1eebng \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn, tuy nhi\u00ean manzamine A c\u00f3 t\u00e1c d\u1ee5ng m\u1ea1nh h\u01a1n 10 l\u1ea7n trong vi\u1ec7c \u1ee9c ch\u1ebf c\u00e1c protein c\u00f3 v\u1ea5n \u0111\u1ec1.<\/p>\n\n\n\n

C\u00e1c m\u00f4 h\u00ecnh m\u00e1y t\u00ednh cho th\u1ea5y manzamine A \u0111\u00e3 t\u00e1c \u0111\u1ed9ng gi\u1ed1ng nh\u01b0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf protein t\u1eebng \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u v\u00e0 s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n ung th\u01b0 nh\u01b0ng m\u1ea1nh g\u1ea5p 10 l\u1ea7n so v\u1edbi nh\u1eefng th\u1ee9 \u0111\u01b0\u1ee3c bi\u1ebft tr\u01b0\u1edbc \u0111\u00e2y.<\/p>\n\n\n\n

Theo Hamann, hi\u1ec7n m\u1ed9t s\u1ed1 \u0111\u01a1n \u0111\u0103ng k\u00fd s\u00e1ng ch\u1ebf manzamine A \u0111\u00e3 \u0111\u01b0\u1ee3c n\u1ed9p, v\u00e0  m\u1ed9t c\u00f4ng ty kh\u1edfi nghi\u1ec7p r\u1ea5t quan t\u00e2m \u0111\u1ebfn nghi\u00ean c\u1ee9u n\u00e0y.<\/p>\n\n\n\n

B\u01b0\u1edbc ti\u1ebfp theo, nh\u00f3m nhi\u00ean c\u1ee9u s\u1ebd thi\u1ebft l\u1eadp c\u00e1c nghi\u00ean c\u1ee9u t\u00e1c d\u1ee5ng c\u1ee7a manzamine A tr\u00ean l\u00e2m s\u00e0ng.<\/p>\n\n\n\n

\u201cM\u1ee5c ti\u00eau hi\u1ec7n gi\u1edd c\u1ee7a ch\u00fang t\u00f4i l\u00e0 \u0111\u1ea3m b\u1ea3o r\u1eb1ng manzamine A ho\u1ea1t \u0111\u1ed9ng hi\u1ec7u qu\u1ea3 tr\u00ean \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m v\u00e0 sau \u0111\u00f3 s\u1ebd c\u1ed1 g\u1eafng ph\u00e1t tri\u1ec3n v\u00e0 \u0111\u01b0a v\u00e0o c\u00e1c \u1ee9ng d\u1ee5ng l\u00e2m s\u00e0ng<\/em>\u201d, Hamann n\u00f3i.<\/p>\n\n\n\n

M\u1eb7c d\u00f9 c\u00e1c ph\u00e2n t\u1eed n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p trong ph\u00f2ng th\u00ed nghi\u1ec7m, tuy nhi\u00ean Hamann kh\u00f4ng ngh\u0129 \u0111\u00f3 l\u00e0 qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p t\u1ed1t nh\u1ea5t.<\/p>\n\n\n\n

\u201cH\u1ea7u h\u1ebft c\u00e1c v\u1eadt li\u1ec7u ban \u0111\u1ea7u \u0111\u1ec3 t\u1ed5ng h\u1ee3p trong<\/em> ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u1ec1u c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb d\u1ea7u m\u1ecf. Ng\u01b0\u1ee3c l\u1ea1i, c\u00e1c lo\u00e0i b\u1ecdt bi\u1ec3n trong m\u00f4i tr\u01b0\u1eddng s\u1ed1ng t\u1ef1 nhi\u00ean c\u1ee7a ch\u00fang c\u00f3 th\u1ec3 nu\u00f4i \u0111\u01b0\u1ee3c th\u00e0nh c\u00f4ng v\u00e0 kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c h\u00ecnh th\u1ee9c nu\u00f4i tr\u1ed3ng th\u1ee7y s\u1ea3n kh\u00e1c, n\u00f3 c\u00f3 th\u1ec3 l\u00e0m s\u1ea1ch m\u00f4i tr\u01b0\u1eddng. Do \u0111\u00f3, vi\u1ec7c s\u1ea3n xu\u1ea5t c\u00e1c ph\u00e2n t\u1eed n\u00e0y t\u1eeb b\u1ecdt bi\u1ec3n trong m\u00f4i tr\u01b0\u1eddng \u0111\u01b0\u1ee3c nu\u00f4i c\u0169ng r\u1ea5t t\u1ed1t, v\u00e0 c\u00f4ng vi\u1ec7c n\u00e0y c\u0169ng t\u1ea1o ra nhi\u1ec1u c\u01a1 h\u1ed9i ph\u00e1t tri\u1ec3n kinh t\u1ebf cho v\u00f9ng n\u00f4ng th\u00f4n In\u0111\u00f4<\/em>n\u00eax<\/em>ia<\/em>\u201d. \u00d4ng gi\u1ea3i th\u00edch.<\/p>\n\n\n\n

Hamann cho r\u1eb1ng, vi\u1ec7c b\u1ea3o t\u1ed3n s\u1ef1 \u0111a d\u1ea1ng lo\u00e0i l\u00e0 v\u00f4 c\u00f9ng quan tr\u1ecdng, gi\u1ed1ng nh\u01b0 b\u1ea3o t\u1ed3n s\u1ef1 \u0111a d\u1ea1ng c\u1ee7a c\u00e1c h\u00f3a ch\u1ea5t m\u00e0 c\u00e1c lo\u00e0i t\u1ea1o ra v\u00e0 c\u1ea3 nh\u1eefng c\u01a1 h\u1ed9i \u0111i\u1ec1u tr\u1ecb ung th\u01b0 m\u00e0 ch\u00fang mang l\u1ea1i. N\u1ebfu bi\u1ebfn \u0111\u1ed5i kh\u00ed h\u1eadu v\u1eabn kh\u00f4ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t, d\u1ef1 \u0111o\u00e1n l\u00e0 ch\u00fang ta c\u00f3 th\u1ec3 m\u1ea5t 1\/3 s\u1ef1 \u0111a d\u1ea1ng lo\u00e0i tr\u00ean to\u00e0n c\u1ea7u. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 khi\u1ebfn ch\u00fang ta m\u1ea5t \u0111i c\u00e1c c\u01a1 h\u1ed9i t\u00ecm ki\u1ebfm c\u00e1c ch\u1ea5t ti\u1ec1m n\u0103ng m\u1edbi.<\/p>\n\n\n\n

P.T.T (NASATI)<\/em><\/p>\n\n\n\n

theo https:\/\/medicalxpress.com\/news\/2020-04-sponges-cancer.html, 4\/4\/2020<\/em><\/p>\n\n\n\n

https:\/\/www.vista.gov.vn\/news\/khoa-hoc-y-duoc\/hop-chat-tim-thay-trong-loai-bot-bien-co-the-chua-ung-thu-2075.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

M\u1ed9t ph\u00e2n t\u1eed c\u00f3 t\u00ean l\u00e0 manzamine A trong lo\u00e0i b\u1ecdt bi\u1ec3n \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y \u1edf V\u1ecbnh Manado, In\u0111\u00f4n\u00eaxia, cho th\u1ea5y kh\u1ea3 n\u0103ng ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 c\u1ed5 t\u1eed cung. C\u00e1c k\u1ebft qu\u1ea3 c\u1ee7a c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u h\u1ee3p t\u00e1c gi\u1eefa Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y South Carolina (MUSC) v\u1edbi […]<\/p>\n","protected":false},"author":25,"featured_media":29759,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-27593","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/27593","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=27593"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/27593\/revisions"}],"predecessor-version":[{"id":29760,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/27593\/revisions\/29760"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/29759"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=27593"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=27593"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=27593"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}