{"id":26675,"date":"2021-02-03T16:49:35","date_gmt":"2021-02-03T09:49:35","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=26675"},"modified":"2022-02-08T10:39:25","modified_gmt":"2022-02-08T03:39:25","slug":"nhung-cong-nghe-tien-tien-giup-con-nguoi-chien-dau-voi-covid-19","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/nhung-cong-nghe-tien-tien-giup-con-nguoi-chien-dau-voi-covid-19\/","title":{"rendered":"Nh\u1eefng c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn gi\u00fap con ng\u01b0\u1eddi chi\u1ebfn \u0111\u1ea5u v\u1edbi Covid-19"},"content":{"rendered":"\n

D\u1ecbch Covid-19 lan r\u1ed9ng kh\u1eafp th\u1ebf gi\u1edbi. Trong cu\u1ed9c chi\u1ebfn n\u00e0y, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 v\u00e0 \u0111ang s\u1eed d\u1ee5ng nh\u1eefng c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn nh\u01b0 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o v\u00e0 \u0111i\u1ec7n to\u00e1n \u0111\u00e1m m\u00e2y, h\u1ed7 tr\u1ee3 x\u1eed l\u00fd d\u1eef li\u1ec7u ng\u0103n ch\u1eb7n virus.<\/strong><\/h2>\n\n\n\n

Vect\u01a1 adenoviral<\/a><\/strong><\/p>\n\n\n\n

Trong nh\u1eefng ng\u00e0y \u0111\u1ea7u c\u1ee7a s\u1ef1 l\u00e2y truy\u1ec1n SARS-CoV-2, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1eeb CanSino Biologics \u1edf Trung Qu\u1ed1c, Johnson & Johnson \u1edf Hoa K\u1ef3, Trung t\u00e2m D\u1ecbch t\u1ec5 h\u1ecdc v\u00e0 Vi sinh v\u1eadt h\u1ecdc Qu\u1ed1c gia Gamaleya \u1edf Nga, v\u00e0 \u0110\u1ea1i h\u1ecdc Oxford (sau \u0111\u00f3 c\u00f3 s\u1ef1 tham gia c\u1ee7a AstraZeneca) \u1edf V\u01b0\u01a1ng qu\u1ed1c Anh b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng vect\u01a1 adenoviral \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u0103cxin Covid-19<\/a>.<\/p>\n\n\n\n

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Vect\u01a1 adenoviral mang m\u00e3 gene m\u1edbi v\u00e0o c\u01a1 th\u1ec3, k\u00edch ho\u1ea1t h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/em><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

C\u00e1c vect\u01a1 adenoviral l\u00e0 phi\u00ean b\u1ea3n r\u1ed7ng c\u1ee7a adenovirus, lo\u1ea1i virus g\u00e2y c\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng. C\u00e1c virus, g\u1ecdi l\u00e0 vect\u01a1 adenoviral, \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 \u0111\u01b0a m\u1ed9t gene t\u1eeb SARS-CoV-2 v\u00e0o c\u01a1 th\u1ec3 con ng\u01b0\u1eddi.<\/p>\n\n\n\n

Theo C&EN, vect\u01a1 adenoviral l\u00e0 c\u00f4ng c\u1ee5 linh ho\u1ea1t m\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc c\u00f3 th\u1ec3 chuy\u1ec3n gene m\u1edbi, ch\u1eb3ng h\u1ea1n nh\u01b0 ADN m\u00e3 h\u00f3a protein \u0111\u1ed9t bi\u1ebfn SARS-CoV-2, v\u00e0o c\u00e1c vect\u01a1 sau \u0111\u00f3 \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y, ph\u00e2n l\u1eadp v\u00e0 \u0111\u00f3ng g\u00f3i th\u00e0nh v\u0103cxin. Nh\u01b0 v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i v\u0103cxin, m\u1ee5c ti\u00eau \u0111\u1eb7t ra l\u00e0 \u0111\u00e1nh l\u1eeba h\u1ec7 mi\u1ec5n d\u1ecbch, khi\u1ebfn c\u01a1 th\u1ec3 x\u00e1c \u0111\u1ecbnh \u0111\u00e3 b\u1ecb nhi\u1ec5m virus.<\/p>\n\n\n\n

Sau khi \u0111\u01b0\u1ee3c ti\u00eam v\u00e0o c\u01a1 th\u1ec3, c\u00e1c vect\u01a1 adenoviral s\u1ebd ch\u00e8n v\u00e0o nh\u1eefng t\u1ebf b\u00e0o v\u00e0 \u0111\u00e1nh l\u1eeba c\u00e1c t\u1ebf b\u1ea3o s\u1ea3n xu\u1ea5t c\u00e1c protein spike (protein d\u1eb1m) c\u1ee7a coronavirus, k\u00edch ho\u1ea1t h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o T, s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ti\u00eau di\u1ec7t coronavirus trong tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m b\u1ec7nh.<\/p>\n\n\n\n

https:\/\/www.youtube.com\/embed\/nXY4NCMf41c<\/a><\/p>\n\n\n\n

Viral vector \u0111\u01b0\u1ee3c ch\u1ebf t\u1ea1o th\u1ebf n\u00e0o.<\/em><\/p>\n\n\n\n

V\u0103cxin RNA Messenger<\/a> (mRNA)<\/strong><\/p>\n\n\n\n

Th\u00e1ng 12\/2020, v\u0103cxin mRNA th\u1ee9 3 \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng Anh, M\u1ef9, Canada v\u00e0 c\u00e1c qu\u1ed1c gia kh\u00e1c. \u0110\u00e2y l\u00e0 m\u1ed9t lo\u1ea1i v\u0103cxin m\u1edbi, b\u1ea3o v\u1ec7 con ng\u01b0\u1eddi kh\u1ecfi nh\u1eefng b\u1ec7nh truy\u1ec1n nhi\u1ec5m nh\u01b0 Covid-19.<\/p>\n\n\n\n

Kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c lo\u1ea1i v\u0103cxin th\u00f4ng th\u01b0\u1eddng, cung c\u1ea5p kh\u1ea3 n\u0103ng mi\u1ec5n d\u1ecbch b\u1eb1ng c\u00e1ch \u0111\u01b0a v\u00e0o c\u01a1 th\u1ec3 m\u1ed9t d\u1ea1ng virus \u0111\u00e3 suy y\u1ebfu, v\u0103cxin mRNA d\u1ea1y c\u00e1c t\u1ebf b\u00e0o ph\u01b0\u01a1ng ph\u00e1p t\u1ea1o ra m\u1ed9t lo\u1ea1i protein, k\u00edch ho\u1ea1t ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch \u0111\u1ec3 t\u1ea1o ra kh\u00e1ng th\u1ec3.<\/p>\n\n\n\n

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Ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng mRNA \u0111\u1ec3 t\u1ea1o ra protein spike, k\u00edch ho\u1ea1t h\u1ec7 mi\u1ec5n d\u1ecbch c\u01a1 th\u1ec3.<\/em><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Theo CDC (Trung t\u00e2m Ki\u1ec3m so\u00e1t v\u00e0 Ph\u00f2ng ng\u1eeba d\u1ecbch b\u1ec7nh Qu\u1ed1c t\u1ebf), v\u0103cxin mRNA l\u00e0 m\u1edbi nh\u01b0ng kh\u00f4ng ph\u1ea3i l\u00e0 ch\u01b0a bi\u1ebft. C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 nghi\u00ean c\u1ee9u mRNA trong nhi\u1ec1u th\u1eadp k\u1ef7 v\u00ec c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n trong ph\u00f2ng th\u00ed nghi\u1ec7m b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c v\u1eadt li\u1ec7u s\u1eb5n c\u00f3, khi\u1ebfn quy tr\u00ecnh \u0111\u01b0\u1ee3c chu\u1ea9n h\u00f3a v\u00e0 m\u1edf r\u1ed9ng \u0111\u1ec3 qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n v\u0103cxin nhanh h\u01a1n so v\u1edbi ph\u00e1t tri\u1ec3n v\u0103cxin truy\u1ec1n th\u1ed1ng.<\/p>\n\n\n\n

https:\/\/www.youtube.com\/embed\/oMXGGmBfkf8<\/a><\/p>\n\n\n\n

V\u0103cxin RNA Messenger (mRNA).<\/em><\/p>\n\n\n\n

C\u00f4ng ngh\u1ec7 n\u00e0y \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong nhi\u1ec1u th\u1eadp k\u1ef7, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u1ea1o ra kh\u00e1ng th\u1ec3 ch\u1ed1ng l\u1ea1i c\u00e1c virus kh\u00e1c, nh\u01b0 virus Zika, b\u1ec7nh d\u1ea1i, c\u00fam v\u00e0 cytomegalovirus (CMV). C\u00f4ng ngh\u1ec7 v\u0103cxin mRNA trong t\u01b0\u01a1ng lai c\u00f3 th\u1ec3 cho ph\u00e9p c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1o ra m\u1ed9t lo\u1ea1i v\u0103cxin \u0111a n\u0103ng, c\u00f3 kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 ch\u1ed1ng l\u1ea1i h\u00e0ng lo\u1ea1t c\u00e1c b\u1ec7nh l\u00e2y nhi\u1ec5m virus kh\u00e1c nhau.<\/p>\n\n\n\n

C\u00f4ng ngh\u1ec7 ch\u1ec9nh s\u1eeda gene CRISPR<\/strong><\/p>\n\n\n\n

C\u00f4ng ngh\u1ec7 CRISPR \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn r\u1ed9ng r\u00e3i v\u1edbi vi\u1ec7c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t c\u00f4ng c\u1ee5 ch\u1ec9nh s\u1eeda gene<\/a>. Nh\u01b0ng trong \u0111\u1ea1i d\u1ecbch, c\u00f4ng ngh\u1ec7 n\u00e0y c\u00f3 m\u1ee5c \u0111\u00edch m\u1edbi l\u00e0 m\u1ed9t gi\u1ea3i ph\u00e1p \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n Covid-19.<\/p>\n\n\n\n

Theo NIH, c\u00e1c ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 CRISPR-Cas c\u00f3 th\u1ec3 ch\u1ea9n \u0111o\u00e1n nhi\u1ec5m tr\u00f9ng SARS-CoV-2 ch\u1ec9 trong m\u1ed9t gi\u1edd. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u coi c\u00f4ng ngh\u1ec7 n\u00e0y nh\u01b0 m\u1ed9t gi\u1ea3i ph\u00e1p thay th\u1ebf \u0111\u1ec3 ph\u00e1t tri\u1ec3n m\u1ed9t k\u1ef9 thu\u1eadt ch\u1ea9n \u0111o\u00e1n nhanh ch\u00f3ng v\u00e0 ch\u00ednh x\u00e1c.<\/p>\n\n\n\n

C\u00e1c nh\u00e0 khoa h\u1ecdc c\u0169ng \u0111ang nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng CRISPR t\u1ea1o ra kh\u1ea3 n\u0103ng \u0111i\u1ec1u tr\u1ecb kh\u00e1ng virus.<\/p>\n\n\n\n

https:\/\/www.youtube.com\/embed\/e7SfWhfKf9s<\/a><\/p>\n\n\n\n

S\u1eed d\u1ee5ng C\u00f4ng ngh\u1ec7 ch\u1ec9nh s\u1eeda gen CRISPR \u0111\u1ec3 ph\u00e1t hi\u1ec7n nhanh Covid-19.<\/em><\/p>\n\n\n\n

Ngay c\u1ea3 v\u1edbi ti\u1ec1m n\u0103ng tr\u1edf th\u00e0nh m\u1ed9t ph\u01b0\u01a1ng th\u1ee9c \u0111i\u1ec1u tr\u1ecb, CRISPR c\u0169ng c\u00f3 th\u1ec3 ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nh\u1eefng kh\u00f3 kh\u0103n r\u1ea5t l\u1edbn \u0111\u1ec3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn th\u1ef1c hi\u1ec7n th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean ng\u01b0\u1eddi.<\/p>\n\n\n\n

Vi\u1ec7c nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh nh\u1eefng r\u1ee7i ro ti\u1ec1m \u1ea9n, li\u00ean quan \u0111\u1ebfn s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 ch\u1ec9nh s\u1eeda gene CRISPR c\u00f3 th\u1ec3 c\u00f3 \u00fd ngh\u0129a quan tr\u1ecdng cho nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ch\u1ed1ng l\u00e2y nhi\u1ec5m trong t\u01b0\u01a1ng lai, sau \u0111\u1ea1i d\u1ecbch Covid-19.<\/p>\n\n\n\n

TH\u00c1I B\u1eb0NG<\/strong><\/p>\n\n\n\n

https:\/\/khoahocdoisong.vn\/nhung-cong-nghe-tien-tien-giup-con-nguoi-chien-dau-voi-covid-19-162335.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

D\u1ecbch Covid-19 lan r\u1ed9ng kh\u1eafp th\u1ebf gi\u1edbi. Trong cu\u1ed9c chi\u1ebfn n\u00e0y, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 v\u00e0 \u0111ang s\u1eed d\u1ee5ng nh\u1eefng c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn nh\u01b0 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o v\u00e0 \u0111i\u1ec7n to\u00e1n \u0111\u00e1m m\u00e2y, h\u1ed7 tr\u1ee3 x\u1eed l\u00fd d\u1eef li\u1ec7u ng\u0103n ch\u1eb7n virus. Vect\u01a1 adenoviral Trong nh\u1eefng ng\u00e0y \u0111\u1ea7u c\u1ee7a s\u1ef1 l\u00e2y truy\u1ec1n SARS-CoV-2, […]<\/p>\n","protected":false},"author":23,"featured_media":26676,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-26675","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=26675"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26675\/revisions"}],"predecessor-version":[{"id":30903,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26675\/revisions\/30903"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/26676"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=26675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=26675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=26675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}