{"id":26490,"date":"2021-01-25T21:15:16","date_gmt":"2021-01-25T14:15:16","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=26490"},"modified":"2021-01-25T21:15:20","modified_gmt":"2021-01-25T14:15:20","slug":"vi-khuan-tu-tinh-phan-phoi-thuoc-dung-vi-tri-bi-benh","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/vi-khuan-tu-tinh-phan-phoi-thuoc-dung-vi-tri-bi-benh\/","title":{"rendered":"Vi khu\u1ea9n t\u1eeb t\u00ednh ph\u00e2n ph\u1ed1i thu\u1ed1c \u0111\u00fang v\u1ecb tr\u00ed b\u1ecb b\u1ec7nh"},"content":{"rendered":"\n

Nh\u1eefng nano\/microrobots v\u1eadn chuy\u1ec3n thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c l\u1ea5y m\u1eabu t\u01b0\u01a1ng t\u1ef1 nh\u01b0 vi khu\u1ea9n v\u1ec1 ph\u01b0\u01a1ng th\u1ee9c chuy\u1ec3n \u0111\u1ed9ng v\u00e0 k\u00edch th\u01b0\u1edbc. Nh\u01b0ng s\u1ebd nh\u01b0 th\u1ebf n\u00e0o n\u1ebfu ch\u00ednh vi khu\u1ea9n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m ch\u1ea5t v\u1eadn chuy\u1ec3n thu\u1ed1c si\u00eau nh\u1ecf?<\/strong><\/h2>\n\n\n\n

M\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n v\u00ec sao nh\u1eefng lo\u1ea1i thu\u1ed1c ch\u1ed1ng ung th\u01b0 th\u01b0\u1eddng g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng v\u00e0 kh\u1eafc nghi\u1ec7t do ho\u1ea1t ch\u1ea5t t\u1ea5n c\u00f4ng t\u1ebf b\u00e0o ung th\u01b0 c\u0169ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn nh\u1eefng t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh.<\/p>\n\n\n\n

Tr\u00ean th\u1ef1c t\u1ebf, r\u1ea5t nhi\u1ec1u lo\u1ea1i thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5, \u0111\u00f3 l\u00e0 l\u00fd do t\u1ea1i sao nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u0103ng c\u01b0\u1eddng nghi\u00ean c\u1ee9u gi\u1ea3i ph\u00e1p ph\u00e2n ph\u1ed1i thu\u1ed1c \u0111\u1ebfn c\u00e1c v\u1ecb tr\u00ed m\u1ee5c ti\u00eau hi\u1ec7u qu\u1ea3 h\u01a1n m\u00e0 kh\u00f4ng t\u1ed5n th\u01b0\u01a1ng cho nh\u1eefng t\u1ebf b\u00e0o v\u00e0 m\u00f4 kh\u1ecfe m\u1ea1nh.<\/p>\n\n\n\n

M\u1ed9t trong nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p ph\u00e2n ph\u1ed1i thu\u1ed1c hi\u1ec7u qu\u1ea3 l\u00e0 s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 nano<\/a>, ch\u1eb3ng h\u1ea1n nh\u01b0 s\u1eed d\u1ee5ng vi\u00ean nang nano\/vi m\u00f4 c\u1ee5 th\u1ec3 cho m\u1ee5c ti\u00eau ho\u1eb7c nano\/microrobots nh\u1eb1m m\u1ee5c \u0111\u00edch gi\u1ea3i ph\u00f3ng thu\u1ed1c ch\u1ec9 khi vi\u00ean nang nano \u0111\u1ebfn v\u1ecb tr\u00ed c\u00e1c t\u1ebf b\u00e0o c\u00f3 b\u1ec7nh. Nh\u1eefng nano\/microrobots n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c l\u1ea5y m\u1eabu t\u01b0\u01a1ng t\u1ef1 nh\u01b0 vi khu\u1ea9n<\/a> v\u1ec1 ph\u01b0\u01a1ng th\u1ee9c chuy\u1ec3n \u0111\u1ed9ng v\u00e0 k\u00edch th\u01b0\u1edbc. <\/p>\n\n\n\n

Nh\u00f3m nh\u00e0 khoa h\u1ecdc t\u1ea1i Vi\u1ec7n K\u1ef9 thu\u1eadt li\u00ean bang Th\u1ee5y S\u0129 (ETH Zurich) do Ph\u00f3 ti\u1ebfn s\u0129\u00a0Simone Sch\u00fcrle \u0111\u00e3 th\u1ef1c hi\u1ec7n m\u1ed9t nghi\u00ean c\u1ee9u theo h\u01b0\u1edbng n\u00e0y n\u00e0y. Trong m\u1ed9t b\u00e0i b\u00e1o, \u0111\u01b0\u1ee3c xu\u1ea5t b\u1ea3n tr\u00ean T\u1ea1p ch\u00ed Advanced Function Materials, Sch\u00fcrle v\u00e0 nh\u00f3m c\u1ee7a b\u00e0 th\u1eed nghi\u1ec7m s\u1eed d\u1ee5ng\u00a0vi khu\u1ea9n t\u1eeb t\u00ednh<\/a>\u00a0nh\u01b0 m\u1ed9t ph\u01b0\u01a1ng ti\u1ec7n ph\u00e2n ph\u1ed1i thu\u1ed1c \u0111\u1ebfn v\u1ecb tr\u00ed c\u1ea7n thi\u1ebft, s\u1eed d\u1ee5ng t\u1eeb tr\u01b0\u1eddng c\u00f3 h\u01b0\u1edbng l\u00e0 \u201cb\u1ea3ng \u0111i\u1ec1u khi\u1ec3n\u201d \u0111\u01b0a vi khu\u1ea9n \u0111\u1ebfn m\u1ee5c ti\u00eau c\u1ea7n tr\u1ecb li\u1ec7u.<\/p>\n\n\n\n

Vi khu\u1ea9n t\u1eeb t\u00ednh ho\u1eb7c vi khu\u1ea9n magneto th\u1ef1c s\u1ef1 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong n\u01b0\u1edbc bi\u1ec3n c\u00e1ch \u0111\u00e2y kho\u1ea3ng 45 n\u0103m. Nh\u1eefng vi sinh v\u1eadt k\u1ef3 l\u1ea1 n\u00e0y h\u1ea5p th\u1ee5 s\u1eaft h\u00f2a tan trong n\u01b0\u1edbc, sau \u0111\u00f3 oxit s\u1eaft k\u1ebft tinh b\u00ean trong vi khu\u1ea9n. Nh\u1eefng tinh th\u1ec3 oxit s\u1eaft n\u00e0y gi\u00fap vi khu\u1ea9n t\u1ef1 \u0111i\u1ec1u ch\u1ec9nh v\u1edbi t\u1eeb tr\u01b0\u1eddng tr\u00e1i \u0111\u1ea5t, \u0111i\u1ec1u h\u01b0\u1edbng trong n\u01b0\u1edbc bi\u1ec3n.<\/p>\n\n\n\n

\"\"<\/td><\/tr>
M\u1ed9t lo\u1ea1i vi khu\u1ea9n thu\u1ed9c gi\u1ed1ng Magnetospirillum. Nh\u1edd m\u1ed9t h\u00e0ng tinh th\u1ec3 oxit s\u1eaft (m\u00e0u v\u00e0ng xanh nh\u1ea1t), nh\u1eefng vi khu\u1ea9n n\u00e0y t\u1ef1 \u0111\u1ecbnh h\u01b0\u1edbng gi\u1ed1ng nh\u01b0 m\u1ed9t chi\u1ebfc kim la b\u00e0n. Vi khu\u1ea9n thu\u1ed9c gi\u1ed1ng n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nghi\u00ean c\u1ee9u d\u1eabn lu\u1ed3ng ch\u1ea5t l\u1ecfng.<\/em><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Nh\u00f3m nh\u00e0 khoa h\u1ecdc Sch\u00fcrle \u0111\u00e3 t\u00e1c \u0111\u1ed9ng m\u1ed9t t\u1eeb tr\u01b0\u1eddng quay y\u1ebfu v\u00e0o nh\u00f3m vi khu\u1ea9n trong ch\u1ea5t l\u1ecfng khi\u1ebfn ch\u00fang ph\u1ea3n \u1ee9ng v\u1edbi t\u1eeb tr\u01b0\u1eddng v\u00e0 di chuy\u1ec3n, cho ph\u00e9p ki\u1ec3m so\u00e1t d\u00f2ng ch\u1ea3y c\u1ee7a ch\u1ea5t l\u1ecfng m\u00e0 vi khu\u1ea9n c\u00f3 trong \u0111\u00f3.<\/p>\n\n\n\n

\u0110i\u1ec1u n\u00e0y t\u1ea1o ra m\u1ed9t hi\u1ec7u \u1ee9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 hi\u1ec7u \u1ee9ng \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi c\u00e1c vi b\u01a1m, do vi khu\u1ea9n d\u01b0\u1edbi t\u00e1c \u0111\u1ed9ng c\u1ee7a t\u1eeb tr\u01b0\u1eddng, c\u00f3 th\u1ec3 di chuy\u1ec3n nh\u1eefng ch\u1ea5t ho\u1ea1t t\u00ednh c\u00f3 trong ch\u1ea5t l\u1ecfng v\u1edbi \u0111\u1ed9 ch\u00ednh x\u00e1c cao. Hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 di chuy\u1ec3n c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u00edch c\u1ef1c trong m\u00e1u tr\u1ef1c ti\u1ebfp \u0111\u1ebfn c\u00e1c v\u1ecb tr\u00ed kh\u1ed1i u.<\/p>\n\n\n\n

B\u00e0 Sch\u00fcrle cho bi\u1ebft, l\u1ee3i th\u1ebf ch\u00ednh c\u1ee7a vi khu\u1ea9n so v\u1edbi nano ho\u1eb7c microrobots l\u00e0 d\u1ec5 s\u1ea3n xu\u1ea5t h\u01a1n; c\u00e1c nh\u00e0 khoa h\u1ecdc ch\u1ec9 c\u1ea7n nu\u00f4i c\u1ea5y vi khu\u1ea9n trong c\u00e1c l\u00f2 ph\u1ea3n \u1ee9ng sinh h\u1ecdc.<\/p>\n\n\n\n

T\u1ea5t nhi\u00ean, \u0111\u00e2y l\u00e0 nh\u1eefng b\u01b0\u1edbc \u0111\u1ea7u ti\u00ean v\u00e0 \u00fd t\u01b0\u1edfng m\u1edbi n\u00e0y ch\u1ec9 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n trong ph\u00f2ng th\u00ed nghi\u1ec7m. \u0110i\u1ec1u ki\u1ec7n c\u1ea7n v\u00e0 \u0111\u1ee7 l\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi trong c\u00e1c gi\u1ea3i ph\u00e1p \u0111i\u1ec1u tr\u1ecb l\u00e2m s\u00e0ng \u0111\u1ed3ng th\u1eddi c\u1ea7n c\u00f3 c\u00e1c bi\u1ec7n ph\u00e1p \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe nghi\u00eam ng\u1eb7t.<\/p>\n\n\n\n

Hi\u1ec7n nay c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u kh\u00e1c \u0111\u00e3 s\u1eed d\u1ee5ng tr\u1ef1c khu\u1ea9n E.coli nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p s\u1ed1ng. Ch\u00ednh v\u00ec v\u1eady, kh\u00f4ng ph\u1ea3i l\u00e0 vi\u1ec5n t\u01b0\u1edfng n\u1ebfu c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c vi khu\u1ea9n nh\u00e2n t\u1ea1o \u0111\u1ec1 th\u1ef1c hi\u1ec7n m\u1ee5c \u0111\u00edch tr\u1ecb li\u1ec7u.<\/p>\n\n\n\n

Nh\u1edd c\u00f3 sinh h\u1ecdc t\u1ed5ng h\u1ee3p, vi khu\u1ea9n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i \u0111\u1ec3 t\u1ed1i \u01b0u h\u00f3a ch\u1ee9c n\u0103ng mong mu\u1ed1n \u2013 gi\u1ea3 thi\u1ebft nh\u01b0 ph\u1ea3n \u1ee9ng v\u1edbi t\u1eeb tr\u01b0\u1eddng so v\u1edbi nh\u1eefng lo\u1ea1i virus s\u1ed1ng \u1edf \u0111\u1ea1i d\u01b0\u01a1ng t\u1ed1t h\u01a1n v\u00e0 c\u00f3 th\u1ec3 l\u00e0nh t\u00ednh h\u01a1n \u0111\u1ec3 s\u1eed d\u1ee5ng trong y t\u1ebf v\u00e0 nh\u1eefng \u1ee9ng d\u1ee5ng tr\u1ecb li\u1ec7u kh\u00e1c.<\/p>\n\n\n\n

Nh\u1eefng k\u1ebft qu\u1ea3 c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y c\u00f2n cho th\u1ea5y m\u1ed1i li\u00ean h\u1ec7 ch\u1eb7t ch\u1ebd gi\u1eefa khoa h\u1ecdc y t\u1ebf v\u00e0 c\u00f4ng ngh\u1ec7 nano trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ti\u00ean ti\u1ebfn, c\u00f3 \u0111\u1ecbnh h\u01b0\u1edbng trong t\u01b0\u01a1ng lai.<\/p>\n\n\n\n

ngu\u1ed3n: khoahocdoisong.vn<\/p>\n","protected":false},"excerpt":{"rendered":"

Nh\u1eefng nano\/microrobots v\u1eadn chuy\u1ec3n thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c l\u1ea5y m\u1eabu t\u01b0\u01a1ng t\u1ef1 nh\u01b0 vi khu\u1ea9n v\u1ec1 ph\u01b0\u01a1ng th\u1ee9c chuy\u1ec3n \u0111\u1ed9ng v\u00e0 k\u00edch th\u01b0\u1edbc. Nh\u01b0ng s\u1ebd nh\u01b0 th\u1ebf n\u00e0o n\u1ebfu ch\u00ednh vi khu\u1ea9n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m ch\u1ea5t v\u1eadn chuy\u1ec3n thu\u1ed1c si\u00eau nh\u1ecf? M\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n v\u00ec sao nh\u1eefng lo\u1ea1i thu\u1ed1c ch\u1ed1ng ung […]<\/p>\n","protected":false},"author":23,"featured_media":26491,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-26490","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=26490"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26490\/revisions"}],"predecessor-version":[{"id":26604,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26490\/revisions\/26604"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/26491"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=26490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=26490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=26490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}