{"id":26200,"date":"2020-09-05T12:08:05","date_gmt":"2020-09-05T05:08:05","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=26200"},"modified":"2021-11-04T09:19:33","modified_gmt":"2021-11-04T02:19:33","slug":"lieu-phap-moi-nham-muc-tieu-ung-thu-vu-di-can-len-nao","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/lieu-phap-moi-nham-muc-tieu-ung-thu-vu-di-can-len-nao\/","title":{"rendered":"Li\u1ec7u ph\u00e1p m\u1edbi nh\u1eafm m\u1ee5c ti\u00eau ung th\u01b0 v\u00fa \u0111i c\u0103n l\u00ean n\u00e3o"},"content":{"rendered":"\n

Khi ung th\u01b0 v\u00fa di c\u0103n l\u00ean n\u00e3o, ti\u00ean l\u01b0\u1ee3ng r\u1ea5t x\u1ea5u. B\u1ec7nh nh\u00e2n ch\u1ec9 c\u00f3 kho\u1ea3ng s\u00e1u th\u00e1ng \u0111\u1ec3 s\u1ed1ng. Ph\u1ee5 n\u1eef b\u1ecb ung th\u01b0 v\u00fa d\u01b0\u01a1ng t\u00ednh v\u1edbi HER2 c\u00f3 xu h\u01b0\u1edbng ph\u00e1t tri\u1ec3n di c\u0103n l\u00ean n\u00e3o trong 55% tr\u01b0\u1eddng h\u1ee3p. Thu\u1ed1c h\u00f3a tr\u1ecb nh\u1eafm v\u00e0o c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa trong n\u00e3o kh\u00f4ng hi\u1ec7u qu\u1ea3 v\u00ec ch\u00fang kh\u00f4ng th\u1ec3 v\u01b0\u1ee3t qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o.<\/p>\n\n\n\n

\"\"\/<\/figure><\/div>\n\n\n\n

Nh\u01b0ng m\u1ed9t li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p m\u1edbi nh\u1eafm v\u00e0o c\u00e1c kh\u1ed1i u ung th\u01b0 v\u00fa \u0111i c\u0103n l\u00ean n\u00e3o \u0111\u00e3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 k\u00edch th\u01b0\u1edbc kh\u1ed1i u v\u00e0 t\u0103ng kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t trong m\u1ed9t nghi\u00ean c\u1ee9u v\u1edbi chu\u1ed9t, theo b\u00e1o c\u00e1o c\u1ee7a m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi c\u1ee7a Northwestern Medicine<\/em>. \u01af\u1edbc t\u00ednh kho\u1ea3ng 75% chu\u1ed9t di c\u0103n n\u00e3o do ung th\u01b0 v\u00fa \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi v\u00e0 kh\u00f4ng c\u00f2n ung th\u01b0 sau li\u1ec7u ph\u00e1p.<\/p>\n\n\n\n

Ti\u1ebfn s\u0129 Maciej Lesniak<\/em> \u0111\u1ebfn t\u1eeb \u0110\u1ea1i h\u1ecdc Northwestern<\/em>, cho bi\u1ebft: “Li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p m\u1edbi m\u00e0 ch\u00fang t\u00f4i x\u00e1c \u0111\u1ecbnh c\u00f3 th\u1ec3 v\u01b0\u1ee3t qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o. Li\u1ec7u ph\u00e1p n\u00e0y c\u0169ng nh\u1eafm v\u00e0o c\u00e1c di c\u0103n n\u00e3o v\u00e0 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t<\/em>\u201d.<\/p>\n\n\n\n

Hai lo\u1ea1i thu\u1ed1c n\u00e0y l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf tubulin, vinorelbine, \u0111\u01b0\u1ee3c C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) ph\u00ea duy\u1ec7t. Ch\u1ea5t \u1ee9c ch\u1ebf bromodomain, I-BET-762, \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn cho c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Ch\u1ea5t \u1ee9c ch\u1ebf bromodomain l\u00e0m t\u0103ng \u03b2III-tubulin, m\u1ed9t lo\u1ea1i protein \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 di c\u0103n \u0111\u1ebfn n\u00e3o. S\u1ef1 bi\u1ec3u hi\u1ec7n qu\u00e1 m\u1ee9c c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 nh\u1ea1y c\u1ea3m v\u1edbi \u03b2III-tubulin s\u1ebd b\u1ecb m\u1ea5t \u0111i do vinorelbine.<\/p>\n\n\n\n

Lesniak cho bi\u1ebft: \u201cNh\u1eefng ph\u00e1t hi\u1ec7n trong c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u c\u1ee7a ch\u00fang t\u00f4i \u0111\u00e3 t\u1ea1o ti\u1ec1n \u0111\u1ec1 cho m\u1ed9t cu\u1ed9c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng, theo \u0111\u00f3 b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00fa di c\u0103n n\u00e3o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a hai lo\u1ea1i thu\u1ed1c n\u00e0y. \u0110i\u1ec1u n\u00e0y s\u1ebd mang l\u1ea1i cho b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00fa di c\u0103n n\u00e3o, nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng m\u1ed9t c\u00e1ch c\u00f3 h\u1ec7 th\u1ed1ng, s\u1ebd c\u00f3 c\u01a1 h\u1ed9i h\u01b0\u1edfng l\u1ee3i t\u1eeb m\u1ed9t ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb m\u1edbi \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 m\u1ea1nh m\u1ebd trong m\u00f4i tr\u01b0\u1eddng th\u1eed nghi\u1ec7m<\/em>\u201d.<\/p>\n\n\n\n

Ung th\u01b0 v\u00fa di c\u0103n \u0111\u1ebfn c\u00e1c c\u01a1 quan kh\u00e1c nh\u01b0 n\u00e3o, ph\u1ed5i v\u00e0 x\u01b0\u01a1ng. Di c\u0103n c\u1ee7a ung th\u01b0 v\u00fa l\u00ean n\u00e3o l\u00e0 c\u0103n b\u1ec7nh giai \u0111o\u1ea1n cu\u1ed1i v\u00e0 l\u00e0 bi\u1ebfn ch\u1ee9ng nguy hi\u1ec3m nh\u1ea5t. T\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u \u0111\u1ea7u ti\u00ean Deepak Kanojia, c\u1ed9ng s\u1ef1 nghi\u00ean c\u1ee9u v\u1ec1 ph\u1eabu thu\u1eadt th\u1ea7n kinh t\u1ea1i Feinberg, cho bi\u1ebft c\u00f2n thi\u1ebfu c\u00e1c li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau cho di c\u0103n n\u00e3o do ung th\u01b0 v\u00fa.<\/p>\n\n\n\n

C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 ph\u00e1t tri\u1ec3n m\u1ed9t m\u00f4 h\u00ecnh chu\u1ed9t c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n nhi\u1ec1u di c\u0103n n\u00e3o \u0111\u1ec3 m\u00f4 ph\u1ecfng nh\u1eefng g\u00ec x\u1ea3y ra \u1edf b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi. H\u1ecd \u0111\u00e3 ti\u00eam c\u00e1c t\u1ebf b\u00e0o kh\u1ed1i u v\u00e0o \u0111\u1ed9ng m\u1ea1ch trong tai, d\u1eabn \u0111\u1ebfn h\u00ecnh th\u00e0nh nhi\u1ec1u kh\u1ed1i u n\u00e3o. Sau khi c\u00e1c kh\u1ed1i u l\u1edbn l\u00ean, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb cho chu\u1ed9t b\u1eb1ng li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p. K\u1ebft qu\u1ea3 cu\u1ed1i c\u00f9ng cho th\u1ea5y 75% s\u1ed1 chu\u1ed9t \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng s\u1ef1 k\u1ebft h\u1ee3p n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi v\u00e0 kh\u00f4ng b\u1ecb ung th\u01b0.<\/p>\n\n\n\n

Ngu\u1ed3n: \u0110.T.V (NASATI)- https:\/\/www.vista.gov.vn\/news\/khoa-hoc-y-duoc\/lieu-phap-moi-nham-muc-tieu-ung-thu-vu-di-can-len-nao-2939.html <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Khi ung th\u01b0 v\u00fa di c\u0103n l\u00ean n\u00e3o, ti\u00ean l\u01b0\u1ee3ng r\u1ea5t x\u1ea5u. B\u1ec7nh nh\u00e2n ch\u1ec9 c\u00f3 kho\u1ea3ng s\u00e1u th\u00e1ng \u0111\u1ec3 s\u1ed1ng. Ph\u1ee5 n\u1eef b\u1ecb ung th\u01b0 v\u00fa d\u01b0\u01a1ng t\u00ednh v\u1edbi HER2 c\u00f3 xu h\u01b0\u1edbng ph\u00e1t tri\u1ec3n di c\u0103n l\u00ean n\u00e3o trong 55% tr\u01b0\u1eddng h\u1ee3p. Thu\u1ed1c h\u00f3a tr\u1ecb nh\u1eafm v\u00e0o c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa […]<\/p>\n","protected":false},"author":23,"featured_media":26201,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-26200","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=26200"}],"version-history":[{"count":4,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26200\/revisions"}],"predecessor-version":[{"id":29398,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/26200\/revisions\/29398"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/26201"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=26200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=26200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=26200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}