{"id":25418,"date":"2020-06-25T08:30:00","date_gmt":"2020-06-25T01:30:00","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=25418"},"modified":"2021-11-09T19:24:43","modified_gmt":"2021-11-09T12:24:43","slug":"hop-chat-trong-cay-rau-meo-uc-che-tieu-duong-ung-thu","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/hop-chat-trong-cay-rau-meo-uc-che-tieu-duong-ung-thu\/","title":{"rendered":"H\u1ee3p ch\u1ea5t trong c\u00e2y r\u00e2u m\u00e8o \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng, ung th\u01b0"},"content":{"rendered":"\n

Nghi\u00ean c\u1ee9u m\u1edbi ph\u00e1t hi\u1ec7n c\u00e2y r\u00e2u m\u00e8o m\u1ecdc nhi\u1ec1u \u1edf mi\u1ec1n n\u00fai Vi\u1ec7t Nam, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 kh\u00e1ng nhi\u1ec1u d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0.<\/p>\n\n\n\n

Nghi\u00ean c\u1ee9u c\u1ee7a TS Nguy\u1ec5n Phi H\u00f9ng v\u00e0 c\u1ed9ng s\u1ef1 Vi\u1ec7n H\u00f3a h\u1ecdc c\u00e1c h\u1ee3p ch\u1ea5t thi\u00ean nhi\u00ean (Vi\u1ec7n H\u00e0n l\u00e2m Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7 Vi\u1ec7t Nam) v\u1eeba c\u00f4ng b\u1ed1 qu\u1ed1c t\u1ebf, t\u00ecm ra nh\u1eefng h\u1ee3p ch\u1ea5t t\u1ef1 nhi\u00ean c\u00f3 ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng trong c\u00e2y r\u00e2u m\u00e8o. C\u00e2y n\u00e0y c\u00f2n c\u00f3 t\u00ean g\u1ecdi kh\u00e1c l\u00e0 b\u00f4ng b\u1ea1c (t\u00ean khoa h\u1ecdc: Orthosiphon stamineus<\/em>), m\u1ed9t lo\u00e0i th\u1ef1c v\u1eadt thu\u1ed9c h\u1ecd b\u1ea1c h\u00e0, ph\u00e2n b\u1ed1 ch\u1ee7 y\u1ebfu \u1edf v\u00f9ng \u0111\u1ed3ng b\u1eb1ng v\u00e0 mi\u1ec1n n\u00fai nh\u01b0 Cao B\u1eb1ng, V\u0129nh L\u1ed9c (Thanh H\u00f3a), Ba V\u00ec (H\u00e0 N\u1ed9i), L\u00e2m \u0110\u1ed3ng.<\/p>\n\n\n\n

\"C\u00e2y
C\u00e2y r\u00e2u m\u00e8o. \u1ea2nh: wikipedia.<\/figcaption><\/figure><\/div>\n\n\n\n

Nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 thu th\u1eadp v\u00e0 t\u00e1ch chi\u1ebft, ph\u00e2n l\u1eadp \u0111\u01b0\u1ee3c 40 h\u1ee3p ch\u1ea5t. Trong s\u1ed1 n\u00e0y 10 h\u1ee3p ch\u1ea5t \u0111\u01b0\u1ee3c nh\u00f3m x\u00e1c \u0111\u1ecbnh c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf ho\u1ea1t l\u1ef1c enzyme protein tyrosine phosphatase 1B (PTP1B). So s\u00e1nh v\u1edbi ch\u1ea5t \u0111\u1ed1i ch\u1ee9ng, 10 h\u1ee3p ch\u1ea5t trong c\u00e2y r\u00e2u m\u00e8o c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf  PTP1B g\u1ea5p 3-4 l\u1ea7n. Enzyme n\u00e0y l\u00e0 y\u1ebfu t\u1ed1 \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp chuy\u1ec3n h\u00f3a \u0111\u01b0\u1eddng, kh\u00f4ng dung n\u1ea1p \u0111\u01b0\u1ee3c gluscose, g\u00e2y ra b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c c\u00e2n b\u1eb1ng.<\/p>\n\n\n\n

\u0110\u1eb7c bi\u1ec7t, hai h\u1ee3p ch\u1ea5t c\u00f3 h\u00e0m l\u01b0\u1ee3ng cao nh\u1ea5t trong c\u00e2y r\u00e2u m\u00e8o (rosmarinic acid v\u00e0 ursolic acid), ngo\u00e0i t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng, c\u00f2n c\u00f3 kh\u1ea3 n\u0103ng ch\u1ed1ng oxy h\u00f3a, kh\u00e1ng nhi\u1ec1u d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0. Ho\u1ea1t t\u00ednh c\u1ee7a ch\u1ea5t n\u00e0y c\u0169ng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong m\u1ed9t s\u1ed1 d\u01b0\u1ee3c li\u1ec7u qu\u00fd, kh\u00f3 tr\u1ed3ng h\u01a1n, nh\u01b0 \u0111an s\u00e2m, x\u1ea1 \u0111en. Tuy nhi\u00ean, gi\u00e1 th\u00e0nh \u0111\u1ec3 thu mua nh\u1eefng d\u01b0\u1ee3c li\u1ec7u qu\u00fd n\u00e0y th\u01b0\u1eddng kh\u00e1 cao trong khi ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf c\u1ee7a h\u1ee3p ch\u1ea5t nh\u01b0 nhau.<\/p>\n\n\n\n

TS H\u00f9ng cho bi\u1ebft, d\u1ef1a v\u00e0o k\u1ebft qu\u1ea3 th\u00ed nghi\u1ec7m, \u00f4ng v\u00e0 c\u1ed9ng s\u1ef1 s\u1ebd nghi\u00ean c\u1ee9u, c\u1ea3i ti\u1ebfn c\u00e1c ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 t\u0103ng hi\u1ec7u su\u1ea5t t\u00e1ch chi\u1ebft \u0111\u1ea1t \u0111\u1ed9 tinh ch\u1ebf cao, k\u1ebft h\u1ee3p v\u1edbi c\u01a1 s\u1edf c\u00e2y tr\u1ed3ng \u0111\u1ec3 thay \u0111\u1ed5i m\u00f4i tr\u01b0\u1eddng sinh tr\u01b0\u1edfng, t\u1eeb \u0111\u00f3 gi\u00fap h\u00e0m l\u01b0\u1ee3ng h\u1ee3p ch\u1ea5t c\u00f3 gi\u00e1 tr\u1ecb \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n.<\/p>\n\n\n\n

\"TS
TS H\u00f9ng \u0111ang th\u1ef1c hi\u1ec7n c\u00f4ng \u0111o\u1ea1n t\u00e1ch chi\u1ebft h\u1ee3p ch\u1ea5t trong ph\u00f2ng th\u00ed nghi\u1ec7m.  \u1ea2nh: NX.<\/figcaption><\/figure><\/div>\n\n\n\n

Hi\u1ec7n nh\u00f3m \u0111ang trong qu\u00e1 tr\u00ecnh nghi\u00ean c\u1ee9u b\u00e0o ch\u1ebf c\u00e1c h\u1ee3p ch\u1ea5t \u1ee9ng d\u1ee5ng l\u00e0m ch\u1ebf ph\u1ea9m h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. Nh\u00f3m nghi\u00ean c\u1ee9u c\u0169ng \u0111\u00e3 nh\u1eadn d\u1ea1ng m\u1ed9t h\u1ee3p ch\u1ea5t m\u1edbi v\u00e0 \u0111ang \u0111i s\u00e2u trong vi\u1ec7c \u0111\u1ecbnh danh v\u00e0 x\u00e1c \u0111\u1ecbnh \u0111\u1eb7c t\u00ednh, ti\u1ec1m n\u0103ng \u1ee9ng d\u1ee5ng c\u1ee7a ch\u1ea5t n\u00e0y.<\/p>\n\n\n\n

C\u00e2y r\u00e2u m\u00e8o hi\u1ec7n \u0111\u01b0\u1ee3c tr\u1ed3ng ph\u1ed5 bi\u1ebfn \u1edf v\u00f9ng n\u00fai ph\u00eda B\u1eafc, c\u00f3 v\u1ecb ng\u1ecdt, t\u00ednh m\u00e1t, t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u, thanh nhi\u1ec7t, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p, b\u1ec7nh \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u trong \u0110\u00f4ng y. C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 h\u00f3a h\u1ecdc v\u00e0 t\u00e1c d\u1ee5ng sinh h\u1ecdc c\u1ee7a r\u00e2u m\u00e8o \u1edf Vi\u1ec7t Nam c\u00f2n h\u1ea1n ch\u1ebf, ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u n\u00e0o v\u1ec1 th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc li\u00ean quan \u0111\u1ebfn ho\u1ea1t t\u00ednh ch\u1ed1ng ti\u1ec3u \u0111\u01b0\u1eddng theo h\u01b0\u1edbng t\u0103ng c\u01b0\u1eddng h\u1ea5p thu \u0111\u01b0\u1eddng m\u00e1u v\u00e0 \u1ee9c ch\u1ebf enzyme PTP1B \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1.<\/p>\n\n\n\n

“Vi\u1ec7c t\u00ecm ra nh\u1eefng h\u1ee3p ch\u1ea5t ti\u1ec1m n\u0103ng, c\u00f3 gi\u00e1 tr\u1ecb trong nh\u1eefng lo\u00e0i c\u00e2y ph\u1ed5 bi\u1ebfn c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m chi ph\u00ed b\u00e0o ch\u1ebf, gi\u00e1 th\u00e0nh d\u01b0\u1ee3c ph\u1ea9m s\u1ebd kh\u00f4ng cao trong khi t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 nh\u01b0 nhau”, TS H\u00f9ng n\u00f3i.<\/p>\n\n\n\n

Nguy\u1ec5n Xu\u00e2n<\/strong> ngu\u1ed3n: vnexpress<\/p>\n\n\n\n

C\u00e2y r\u00e2u m\u00e8o c\u00f3 ho\u1ea1t ch\u1ea5t qu\u00fd \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng (vnexpress.net)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Nghi\u00ean c\u1ee9u m\u1edbi ph\u00e1t hi\u1ec7n c\u00e2y r\u00e2u m\u00e8o m\u1ecdc nhi\u1ec1u \u1edf mi\u1ec1n n\u00fai Vi\u1ec7t Nam, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 kh\u00e1ng nhi\u1ec1u d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0. Nghi\u00ean c\u1ee9u c\u1ee7a TS Nguy\u1ec5n Phi H\u00f9ng v\u00e0 c\u1ed9ng s\u1ef1 Vi\u1ec7n H\u00f3a h\u1ecdc c\u00e1c h\u1ee3p ch\u1ea5t thi\u00ean nhi\u00ean (Vi\u1ec7n H\u00e0n l\u00e2m Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7 Vi\u1ec7t Nam) […]<\/p>\n","protected":false},"author":25,"featured_media":25419,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-25418","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/25418","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=25418"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/25418\/revisions"}],"predecessor-version":[{"id":29836,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/25418\/revisions\/29836"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/25419"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=25418"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=25418"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=25418"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}