{"id":24964,"date":"2020-05-13T09:42:00","date_gmt":"2020-05-13T02:42:00","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=24964"},"modified":"2021-11-08T21:27:17","modified_gmt":"2021-11-08T14:27:17","slug":"nghien-cuu-dot-bien-gene-sars-cov-2-de-phat-trien-thuoc","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/nghien-cuu-dot-bien-gene-sars-cov-2-de-phat-trien-thuoc\/","title":{"rendered":"Nghi\u00ean c\u1ee9u \u0111\u1ed9t bi\u1ebfn gene SARS-CoV-2 \u0111\u1ec3 ph\u00e1t tri\u1ec3n thu\u1ed1c"},"content":{"rendered":"\n

(khoahocdoisong.vn) – B\u1eb1ng c\u00e1ch ph\u00e2n t\u00edch b\u1ed9 gene c\u1ee7a virus t\u1eeb h\u01a1n 7.500 ng\u01b0\u1eddi b\u1ecb nhi\u1ec5m Covid-19, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u01b0a ra c\u1ea5u tr\u00fac c\u00e1c ki\u1ec3u gene \u0111a d\u1ea1ng c\u1ee7a virus SARS-CoV-2, x\u00e1c \u0111\u1ecbnh nh\u1eefng m\u1ee5c ti\u00eau c\u1ee5 th\u1ec3 cho thu\u1ed1c v\u00e0 v\u0103cxin.<\/strong><\/h2>\n\n\n\n

T\u1eadp trung v\u00e0o ph\u1ea7n gene \u00edt bi\u1ebfn \u0111\u1ed5i<\/strong><\/p>\n\n\n\n

Vi\u1ec7n Di truy\u1ec1n UCL, k\u1ebft h\u1ee3p v\u1edbi c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1eeb c\u01a1 s\u1edf Nghi\u00ean c\u1ee9u kh\u00e1c t\u1ea1i V\u01b0\u01a1ng qu\u1ed1c Anh trong m\u1ed9t c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y x\u00e1c \u0111\u1ecbnh g\u1ea7n 200 \u0111\u1ed9t bi\u1ebfn gene li\u00ean ti\u1ebfp xu\u1ea5t hi\u1ec7n theo chu k\u1ef3 \u1edf virus, cho th\u1ea5y coronavirus m\u1edbi r\u1ea5t nhanh ch\u00f3ng th\u00edch nghi v\u00e0 ti\u1ebfn h\u00f3a v\u1edbi v\u1eadt ch\u1ee7 con ng\u01b0\u1eddi<\/a> trong nh\u1eefng m\u00f4i tr\u01b0\u1eddng kh\u00e1c nhau.<\/p>\n\n\n\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c m\u1ed9t t\u1ef7 l\u1ec7 l\u1edbn s\u1ef1 \u0111a d\u1ea1ng di truy\u1ec1n to\u00e0n c\u1ea7u c\u1ee7a SARS-CoV-2 trong h\u1ea7u h\u1ebft c\u00e1c qu\u1ed1c gia ch\u1ecbu \u1ea3nh h\u01b0\u1edfng n\u1eb7ng n\u1ec1 nh\u1ea5t, cho th\u1ea5y s\u1ef1 l\u00e2y truy\u1ec1n to\u00e0n c\u1ea7u t\u1eeb s\u1edbm trong d\u1ecbch b\u1ec7nh v\u00e0 kh\u00f4ng c\u00f3 B\u1ec7nh nh\u00e2n s\u1ed1 “0” \u1edf h\u1ea7u h\u1ebft c\u00e1c qu\u1ed1c gia.<\/p>\n\n\n\n

C\u00e1c nh\u00e0 khoa h\u1ecdc ch\u1ee9ng minh \u0111\u01b0\u1ee3c s\u1ef1 \u0111a d\u1ea1ng gene trong SARS-CoV-2 b\u1eb1ng gi\u1ea3i ph\u00e1p ph\u00e2n t\u00edch v\u00e0 s\u00e0ng l\u1ecdc b\u1ed9 gene c\u1ee7a h\u01a1n 7.500 virus t\u1eeb nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m tr\u00ean to\u00e0n c\u1ea7u.<\/p>\n\n\n\n

Nh\u00f3m nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c 198 \u0111\u1ed9t bi\u1ebfn c\u1ee5 th\u1ec3, xu\u1ea5t hi\u1ec7n \u0111\u1ed9c l\u1eadp h\u01a1n m\u1ed9t l\u1ea7n. Ph\u00e1t hi\u1ec7n n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn manh m\u1ed1i v\u1ec1 ph\u01b0\u01a1ng th\u1ee9c virus th\u00edch nghi v\u1edbi s\u1ef1 bi\u1ebfn \u0111\u1ed5i m\u00f4i tr\u01b0\u1eddng s\u1ed1ng c\u1ee7a v\u1eadt ch\u1ee7.<\/p>\n\n\n\n

\u0110\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u, GS Francois Balloux thu\u1ed9c Vi\u1ec7n Di truy\u1ec1n h\u1ecdc UCL cho bi\u1ebft, t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i virus \u0111\u1ec1u bi\u1ebfn \u0111\u1ed5i t\u1ef1 nhi\u00ean. B\u1ea3n th\u00e2n \u0111\u1ed9t bi\u1ebfn kh\u00f4ng ph\u1ea3i l\u00e0 s\u1ef1 c\u1ed1 \u0111\u1eb7c bi\u1ec7t, kh\u00f4ng c\u00f3 g\u00ec cho th\u1ea5y SARS-CoV-2 \u0111ang bi\u1ebfn \u0111\u1ed5i nhanh h\u01a1n ho\u1eb7c ch\u1eadm h\u01a1n so v\u1edbi d\u1ef1 ki\u1ebfn c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc. \u0110i\u1ec3m \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng thay \u0111\u1ed5i di truy\u1ec1n nh\u1ecf, ho\u1eb7c \u0111\u1ed9t bi\u1ebfn \u0111\u01b0\u1ee3c nh\u00f3m nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh l\u00e0 kh\u00f4ng ph\u00e2n b\u1ed1 \u0111\u1ec1u tr\u00ean to\u00e0n b\u1ed9 b\u1ed9 gene c\u1ee7a virus m\u00e0 ch\u1ec9 \u1edf m\u1ed9t s\u1ed1 ph\u1ea7n nh\u1ea5t \u0111\u1ecbnh.<\/p>\n\n\n\n

C\u00f3 m\u1ed9t s\u1ed1 b\u1ed9 ph\u1eadn c\u1ee7a b\u1ed9 gene kh\u00f4ng c\u00f3 ho\u1eb7c c\u00f3 r\u1ea5t \u00edt \u0111\u1ed9t bi\u1ebfn, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho r\u1eb1ng, nh\u1eefng ph\u1ea7n b\u1ea5t bi\u1ebfn c\u1ee7a b\u1ed9 gene virus c\u00f3 th\u1ec3 l\u00e0 m\u1ee5c ti\u00eau t\u1ed1t nh\u1ea5t cho vi\u1ec7c ph\u00e1t tri\u1ec3n thu\u1ed1c<\/a> v\u00e0 v\u0103cxin.<\/p>\n\n\n\n

GS Balloux gi\u1ea3i th\u00edch: “M\u1ed9t th\u00e1ch th\u1ee9c l\u1edbn \u0111\u1ed1i v\u1edbi vi\u1ec7c ti\u00eau di\u1ec7t virus l\u00e0 v\u0103cxin ho\u1eb7c thu\u1ed1c c\u00f3 th\u1ec3 kh\u00f4ng c\u00f2n hi\u1ec7u qu\u1ea3 n\u1ebfu virus \u0111\u00e3 \u0111\u1ed9t bi\u1ebfn. N\u1ebfu \u0111\u1eb7t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb, t\u1eadp trung v\u00e0o nh\u1eefng ph\u1ea7n gene virus \u00edt c\u00f3 kh\u1ea3 n\u0103ng bi\u1ebfn \u0111\u1ed5i, ch\u00fang ta c\u00f3 c\u01a1 h\u1ed9i ph\u00e1t tri\u1ec3n c\u00e1c lo\u1ea1i thu\u1ed1c, c\u00f3 hi\u1ec7u qu\u1ea3 l\u00e2u d\u00e0i h\u01a1n v\u00e0 \u0111i\u1ec1u tr\u1ecb t\u1ed1t h\u01a1n”.<\/p>\n\n\n\n

Ngu\u1ed3n m\u1edf \u0111\u1ec3 chia s\u1ebb th\u00f4ng tin<\/strong><\/p>\n\n\n\n

\u0110\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u, TS Lucy van Dorp, c\u0169ng thu\u1ed9c Vi\u1ec7n Di truy\u1ec1n h\u1ecdc UCL cho bi\u1ebft, v\u1eabn c\u00f2n r\u1ea5t \u00edt s\u1ef1 kh\u00e1c bi\u1ec7t di truy\u1ec1n ho\u1eb7c \u0111\u1ed9t bi\u1ebfn gi\u1eefa c\u00e1c virus c\u00f9ng ch\u00f9ng lo\u1ea1i SARS-CoV-2. C\u00f3 m\u1ed9t s\u1ed1 \u0111\u1ed9t bi\u1ebfn gene x\u1ea3y ra nhi\u1ec1u l\u1ea7n, \u0111\u1ed9c l\u1eadp trong qu\u00e1 tr\u00ecnh di\u1ec5n ra \u0111\u1ea1i d\u1ecbch, \u0111i\u1ec1u \u0111\u00f3 c\u00f3 ngh\u0129a l\u00e0 c\u1ea7n ti\u1ebfp t\u1ee5c theo d\u00f5i nh\u1eefng bi\u1ebfn \u0111\u1ed5i n\u00e0y.<\/p>\n\n\n\n

Nh\u1eefng k\u1ebft qu\u1ea3 ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c \u0111\u00e3 cho th\u1ea5y,  r\u1ea5t c\u00f3 th\u1ec3 virus g\u00e2y ra Covid-19 \u0111\u00e3 t\u1ed3n t\u1ea1i t\u1ef1 nhi\u00ean trong th\u1eddi gian d\u00e0i tr\u01b0\u1edbc khi ph\u00e1t hi\u1ec7n l\u1ea7n \u0111\u1ea7u ti\u00ean tr\u00ean ng\u01b0\u1eddi.<\/p>\n\n\n\n

\"\"\/<\/figure><\/div>\n\n\n\n

\u1ede nhi\u1ec1u qu\u1ed1c gia, bao g\u1ed3m c\u1ea3 V\u01b0\u01a1ng qu\u1ed1c Anh, s\u1ef1 \u0111a d\u1ea1ng c\u1ee7a c\u00e1c lo\u1ea1i virus \u0111\u01b0\u1ee3c l\u1ea5y m\u1eabu g\u1ea7n nh\u01b0 c\u00f3 tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, c\u00f3 ngh\u0129a l\u00e0 virus n\u00e0y x\u00e2m nh\u1eadp v\u00e0o V\u01b0\u01a1ng qu\u1ed1c Anh nhi\u1ec1u l\u1ea7n m\u1ed9t c\u00e1ch \u0111\u1ed9c l\u1eadp, ch\u1ee9 kh\u00f4ng ph\u1ea3i l\u00e0 nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c th\u00f9 n\u00e0o (B\u1ec7nh nh\u00e2n s\u1ed1 \u201c0\u201d).<\/p>\n\n\n\n

T\u1eeb ph\u00e1t hi\u1ec7n n\u00e0y, nh\u00f3m nghi\u00ean c\u1ee9u ph\u00e1t tri\u1ec3n m\u1ed9t \u1ee9ng d\u1ee5ng tr\u1ef1c tuy\u1ebfn, ngu\u1ed3n m\u1edf t\u01b0\u01a1ng t\u00e1c m\u1edbi \u0111\u1ec3 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u tr\u00ean to\u00e0n c\u1ea7u c\u0169ng c\u00f3 th\u1ec3 truy c\u1eadp, nghi\u00ean c\u1ee9u \u0111\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 s\u1ef1 ti\u1ebfn h\u00f3a v\u00e0 \u0111\u1ed9t bi\u1ebfn gene c\u1ee7a SARS-CoV-2.<\/p>\n\n\n\n

Theo TS\u00a0van Dorp, vi\u1ec7c c\u00f3 th\u1ec3 ph\u00e2n t\u00edch m\u1ed9t s\u1ed1 l\u01b0\u1ee3ng genome virus phi th\u01b0\u1eddng nh\u01b0 v\u1eady trong v\u00e0i th\u00e1ng \u0111\u1ea7u c\u1ee7a \u0111\u1ea1i d\u1ecbch c\u00f3 th\u1ec3 l\u00e0 v\u00f4 gi\u00e1 \u0111\u1ed1i v\u1edbi nh\u1eefng n\u1ed7 l\u1ef1c ph\u00e1t tri\u1ec3n thu\u1ed1c v\u00e0 cho th\u1ea5y, l\u0129nh v\u1ef1c nghi\u00ean c\u1ee9u gene \u0111\u00e3 ti\u1ebfn r\u1ea5t xa trong th\u1eadp k\u1ef7 qua nh\u1edd nh\u1eefng \u1ee9ng d\u1ee5ng c\u00f4ng ngh\u1ec7 m\u1edbi.<\/p>\n\n\n\n

TH\u00c1I B\u1eb0NG<\/p>\n\n\n\n

Nghi\u00ean c\u1ee9u \u0111\u1ed9t bi\u1ebfn gen SARS-CoV-2 t\u1ea1o n\u1ec1n t\u00e0ng ph\u00e1t tri\u1ec3n thu\u1ed1c – Khoa h\u1ecdc v\u00e0 \u0111\u1eddi s\u1ed1ng (khoahocdoisong.vn)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

(khoahocdoisong.vn) – B\u1eb1ng c\u00e1ch ph\u00e2n t\u00edch b\u1ed9 gene c\u1ee7a virus t\u1eeb h\u01a1n 7.500 ng\u01b0\u1eddi b\u1ecb nhi\u1ec5m Covid-19, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u01b0a ra c\u1ea5u tr\u00fac c\u00e1c ki\u1ec3u gene \u0111a d\u1ea1ng c\u1ee7a virus SARS-CoV-2, x\u00e1c \u0111\u1ecbnh nh\u1eefng m\u1ee5c ti\u00eau c\u1ee5 th\u1ec3 cho thu\u1ed1c v\u00e0 v\u0103cxin. T\u1eadp trung v\u00e0o ph\u1ea7n gene \u00edt bi\u1ebfn \u0111\u1ed5i Vi\u1ec7n Di truy\u1ec1n […]<\/p>\n","protected":false},"author":25,"featured_media":24965,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-24964","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24964","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=24964"}],"version-history":[{"count":4,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24964\/revisions"}],"predecessor-version":[{"id":29729,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24964\/revisions\/29729"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/24965"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=24964"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=24964"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=24964"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}