{"id":24944,"date":"2020-05-12T09:36:00","date_gmt":"2020-05-12T02:36:00","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=24944"},"modified":"2021-11-08T21:38:38","modified_gmt":"2021-11-08T14:38:38","slug":"phat-trien-he-nano-de-thuoc-hap-thu-nhanh-hon","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/phat-trien-he-nano-de-thuoc-hap-thu-nhanh-hon\/","title":{"rendered":"Ph\u00e1t tri\u1ec3n h\u1ec7 nano \u0111\u1ec3 thu\u1ed1c h\u1ea5p th\u1ee5 nhanh h\u01a1n"},"content":{"rendered":"\n

C\u00e1c nh\u00e0 khoa h\u1ecdc Vi\u1ec7t b\u01b0\u1edbc \u0111\u1ea7u ph\u00e1t tri\u1ec3n h\u1ec7 d\u1eabn thu\u1ed1c g\u1ecdi l\u00e0 “h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a” \u0111\u1ec3 \u1ee9ng d\u1ee5ng gi\u00fap ng\u01b0\u1eddi b\u1ec7nh h\u1ea5p thu d\u01b0\u1ee3c ch\u1ea5t t\u1ed1t h\u01a1n.<\/p>\n\n\n\n

C\u00f4ng th\u1ee9c b\u00e0o ch\u1ebf h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a si\u00eau b\u00e3o h\u00f2a ch\u1ee9a silymarin do TS Nguy\u1ec5n Th\u1ea1ch T\u00f9ng (38 tu\u1ed5i), \u0110\u1ea1i h\u1ecdc D\u01b0\u1ee3c H\u00e0 N\u1ed9i v\u00e0 c\u1ed9ng s\u1ef1 th\u1ef1c hi\u1ec7n. \u1ede c\u00e1c lo\u1ea1i thu\u1ed1c hi\u1ec7n nay th\u01b0\u1eddng d\u00f9ng d\u1eabn ch\u1ea5t truy\u1ec1n th\u1ed1ng c\u00f3 t\u00ean l\u00e0 silymarin, chi\u1ebft xu\u1ea5t t\u1eeb c\u00e2y c\u1ecf s\u1eefa silybum marianum, c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a, ch\u1ed1ng ung th\u01b0, b\u1ea3o v\u1ec7 gan, tim m\u1ea1ch.<\/p>\n\n\n\n

Tuy nhi\u00ean silymarin c\u00f3 \u0111\u1ed9 tan trong n\u01b0\u1edbc th\u1ea5p, kh\u1ea3 n\u0103ng th\u1ea5m k\u00e9m, chuy\u1ec3n h\u00f3a qua gan nhi\u1ec1u, th\u1ea3i tr\u1eeb nhanh, khi\u1ebfn t\u1ed1c \u0111\u1ed9 v\u00e0 m\u1ee9c \u0111\u1ed9 h\u1ea5p thu d\u01b0\u1ee3c ch\u1ea5t, t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd b\u1ecb h\u1ea1n ch\u1ebf. T\u1ea1i Vi\u1ec7t Nam, d\u01b0\u1ee3c li\u1ec7u n\u00e0y \u0111\u01b0\u1ee3c ch\u1ee7 y\u1ebfu b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n ho\u1eb7c vi\u00ean nang n\u00ean hi\u1ec7u qu\u1ea3 b\u1ea3o v\u1ec7 gan th\u01b0\u1eddng ch\u01b0a cao.<\/p>\n\n\n\n

TS T\u00f9ng \u0111\u00e3 ph\u00e1t tri\u1ec3n h\u1ec7 d\u1eabn thu\u1ed1c m\u1edbi, h\u1ec7 n\u00e0y c\u00f3 \u0111\u1eb7c \u0111i\u1ec3m khi pha lo\u00e3ng v\u1edbi n\u01b0\u1edbc ho\u1eb7c d\u1ecbch ti\u00eau h\u00f3a ch\u1ec9 c\u1ea7n khu\u1ea5y tr\u1ed9n nh\u1eb9 nh\u00e0ng s\u1ebd t\u1ef1 nh\u0169 h\u00f3a v\u00e0 t\u1ea1o ra gi\u1ecdt nano nh\u0169 t\u01b0\u01a1ng mang thu\u1ed1c c\u00f3 k\u00edch th\u01b0\u1edbc \u1edf v\u00f9ng kho\u1ea3ng 200 nanomet \u0111\u1ec3 mang ho\u1ea1t ch\u1ea5t c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb d\u01b0\u1ee3c li\u1ec7u silymarin. <\/p>\n\n\n\n

\"TS
TS Nguy\u1ec5n Th\u1ea1ch T\u00f9ng (gi\u1eefa) c\u00f9ng sinh vi\u00ean \u0110\u1ea1i h\u1ecdc D\u01b0\u1ee3c H\u00e0 N\u1ed9i. \u1ea2nh: NVCC.<\/figcaption><\/figure><\/div>\n\n\n\n

Khi s\u1eed d\u1ee5ng ch\u1ea5t mang thu\u1ed1c n\u00e0y s\u1ebd n\u00e2ng cao t\u00e1c d\u1ee5ng cho c\u00e1c d\u01b0\u1ee3c ch\u1ea5t k\u00e9m tan, k\u00e9m th\u1ea5m nh\u01b0 thu\u1ed1c kh\u00e1ng virus, kh\u00e1ng n\u1ea5m. Khi s\u1eed d\u1ee5ng s\u1ebd gi\u00fap ng\u01b0\u1eddi b\u1ec7nh gi\u1ea3m th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u00e0 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n, t\u1eeb \u0111\u00f3 gi\u1ea3m chi ph\u00ed \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi d\u00f9ng.  <\/p>\n\n\n\n

Theo TS T\u00f9ng, so v\u1edbi h\u1ec7 mang thu\u1ed1c truy\u1ec1n th\u1ed1ng, h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a c\u00f3 k\u00edch th\u01b0\u1edbc nh\u1ecf, di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t ti\u1ebfp x\u00fac v\u1edbi bi\u1ec3u m\u00f4 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a l\u1edbn gi\u00fap c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a d\u01b0\u1ee3c ch\u1ea5t v\u00e0 n\u00e2ng cao hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb, gi\u1ea3m li\u1ec1u v\u00e0 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a d\u01b0\u1ee3c ch\u1ea5t. Ngo\u00e0i ra, h\u1ec7 n\u00e0y d\u1ec5 \u1ee9ng d\u1ee5ng v\u00e0o s\u1ea3n xu\u1ea5t th\u1ef1c t\u1ebf tr\u00ean d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t thu\u1ed1c nang m\u1ec1m.<\/p>\n\n\n\n

Th\u00f4ng qua t\u1ed1i \u01b0u h\u00f3a c\u00f4ng th\u1ee9c v\u1ecf nang m\u1ec1m v\u00e0 d\u1ecbch nh\u00e2n l\u00e0 h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a, hi\u1ec7n nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e2y d\u1ef1ng th\u00e0nh c\u00f4ng c\u00f4ng th\u1ee9c nh\u00e2n v\u00e0 v\u1ecf vi\u00ean nang m\u1ec1m ch\u1ee9a h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a v\u00e0 s\u1ea3n xu\u1ea5t th\u1eed nghi\u1ec7m 5.000 vi\u00ean nang m\u1ec1m \u1edf quy m\u00f4 c\u00f4ng nghi\u1ec7p b\u1eb1ng m\u00e1y \u0111\u00f3ng nang m\u1ec1m \u00e9p khu\u00f4n.<\/p>\n\n\n\n

Thi\u1ebft k\u1ebf h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a, TS T\u00f9ng v\u00e0 c\u1ed9ng s\u1ef1 \u0111\u00e3 t\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p tr\u00e1ng phim \u0111\u1ec3 quan s\u00e1t \u1ea3nh h\u01b0\u1edfng c\u1ee7a polyme t\u1edbi silymarin \u1edf tr\u1ea1ng th\u00e1i r\u1eafn v\u00e0 chuy\u1ec3n dung m\u00f4i nh\u1eb1m \u0111\u00e1nh gi\u00e1 \u1ea3nh h\u01b0\u1edfng polyme t\u1edbi silymarin \u1edf tr\u1ea1ng th\u00e1i l\u1ecfng. <\/p>\n\n\n\n

“\u0110\u00e2y l\u00e0 hai ph\u01b0\u01a1ng ph\u00e1p thi\u1ebft k\u1ebf ch\u01b0a t\u1eebng \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng tr\u01b0\u1edbc \u0111\u00f3, gi\u00fap kh\u1eafc ph\u1ee5c d\u01b0\u1ee3c ch\u1ea5t b\u1ecb k\u1ebft t\u1ee7a, t\u00e1ch ra kh\u1ecfi nano nh\u0169 h\u00f3a trong qu\u00e1 tr\u00ecnh b\u1ea3o qu\u1ea3n v\u00e0 s\u1eed d\u1ee5ng c\u1ee7a h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a”, TS T\u00f9ng n\u00f3i. Hi\u1ec7n nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 g\u1eedi h\u1ed3 s\u01a1 c\u00f4ng b\u1ed1 s\u1ea3n ph\u1ea9m t\u1edbi C\u1ee5c An to\u00e0n th\u1ef1c ph\u1ea9m, B\u1ed9 Y t\u1ebf v\u00e0 \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn v\u1edbi s\u1ea3n ph\u1ea9m vi\u00ean nang m\u1ec1m \u1edf giai \u0111o\u1ea1n th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng, c\u00f3 t\u00e1c d\u1ee5ng h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng gan v\u00e0 tim m\u1ea1ch.<\/p>\n\n\n\n

“\u0110\u1ec3 ti\u1ebfp t\u1ee5c kh\u1eb3ng \u0111\u1ecbnh \u00fd ngh\u0129a, hi\u1ec7u qu\u1ea3 c\u1ee7a h\u1ec7 d\u1eabn thu\u1ed1c m\u1edbi n\u00e0y, c\u1ea7n ti\u1ebfp t\u1ee5c ti\u1ebfn h\u00e0nh c\u00e1c \u0111\u00e1nh gi\u00e1 \u1edf m\u1ee9c \u0111\u1ed9 cao h\u01a1n nh\u01b0 th\u1ea9m \u0111\u1ecbnh \u0111\u1ea7y \u0111\u1ee7 quy tr\u00ecnh s\u1ea3n xu\u1ea5t, nghi\u00ean c\u1ee9u \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh d\u00e0i h\u1ea1n v\u00e0 c\u00e1c th\u1eed nghi\u1ec7m sinh h\u1ecdc theo quy \u0111\u1ecbnh cho c\u00f4ng b\u1ed1 m\u1ed9t thu\u1ed1c m\u1edbi”, TS T\u00f9ng cho bi\u1ebft.<\/p>\n\n\n\n

Do t\u00ednh \u1ee9ng d\u1ee5ng c\u1ee7a c\u00f4ng tr\u00ecnh trong vi\u1ec7c ph\u00e1t tri\u1ec3n lo\u1ea1i thu\u1ed1c m\u1edbi, nghi\u00ean c\u1ee9u n\u00e0y \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn \u0111\u1ec1 c\u1eed ch\u00ednh gi\u1ea3i th\u01b0\u1edfng T\u1ea1 Quang B\u1eedu 2020 c\u1ee7a B\u1ed9 Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7. K\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u \u0111\u00e3 \u0111\u0103ng tr\u00ean t\u1ea1p ch\u00ed International Journal of Pharmaceutics (t\u1ea1p ch\u00ed uy t\u00edn trong l\u0129nh v\u1ef1c B\u00e0o ch\u1ebf thu\u1ed1c). <\/p>\n\n\n\n

Nguy\u1ec5n Xu\u00e2n<\/strong> ngu\u1ed3n: vnexpress.net<\/p>\n\n\n\n

Ph\u00e1t tri\u1ec3n h\u1ec7 nano \u0111\u1ec3 thu\u1ed1c h\u1ea5p th\u1ee5 nhanh h\u01a1n – VnExpress<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 khoa h\u1ecdc Vi\u1ec7t b\u01b0\u1edbc \u0111\u1ea7u ph\u00e1t tri\u1ec3n h\u1ec7 d\u1eabn thu\u1ed1c g\u1ecdi l\u00e0 “h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a” \u0111\u1ec3 \u1ee9ng d\u1ee5ng gi\u00fap ng\u01b0\u1eddi b\u1ec7nh h\u1ea5p thu d\u01b0\u1ee3c ch\u1ea5t t\u1ed1t h\u01a1n. C\u00f4ng th\u1ee9c b\u00e0o ch\u1ebf h\u1ec7 nano t\u1ef1 nh\u0169 h\u00f3a si\u00eau b\u00e3o h\u00f2a ch\u1ee9a silymarin do TS Nguy\u1ec5n Th\u1ea1ch T\u00f9ng (38 tu\u1ed5i), \u0110\u1ea1i h\u1ecdc D\u01b0\u1ee3c H\u00e0 N\u1ed9i […]<\/p>\n","protected":false},"author":25,"featured_media":24945,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-24944","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24944","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=24944"}],"version-history":[{"count":3,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24944\/revisions"}],"predecessor-version":[{"id":29735,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/24944\/revisions\/29735"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/24945"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=24944"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=24944"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=24944"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}