{"id":13903,"date":"2018-09-17T08:28:52","date_gmt":"2018-09-17T01:28:52","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=13903"},"modified":"2018-09-17T08:28:52","modified_gmt":"2018-09-17T01:28:52","slug":"mot-vac-xin-ung-thu-cho-hieu-qua-100-trong-thu-nghiem-tren-chuot","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/mot-vac-xin-ung-thu-cho-hieu-qua-100-trong-thu-nghiem-tren-chuot\/","title":{"rendered":"M\u1ed9t v\u1eafc-xin ung th\u01b0 cho hi\u1ec7u qu\u1ea3 100% trong th\u1eed nghi\u1ec7m tr\u00ean chu\u1ed9t"},"content":{"rendered":"

“Li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p n\u00e0y cung c\u1ea5p m\u1ed9t \u0111\u00e1p \u1ee9ng ho\u00e0n to\u00e0n – m\u1ed9t \u0111\u00e1p \u1ee9ng c\u00f3 th\u1ec3 ch\u1eefa kh\u1ecfi- trong \u0111i\u1ec1u tr\u1ecb u h\u1eafc t\u1ed1”.<\/h2>\n
M\u1ed9t nghi\u00ean c\u1ee9u v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 trong K\u1ef7 y\u1ebfu Vi\u1ec7n H\u00e0n l\u00e2m Khoa h\u1ecdc Hoa K\u1ef3 (PNAS) s\u1ebd mang \u0111\u1ebfn tin vui cho c\u00e1c b\u1ec7nh nh\u00e2n ung th\u01b0 da, c\u1ee5 th\u1ec3 l\u00e0 nh\u1eefng ng\u01b0\u1eddi m\u1eafc u h\u1eafc t\u1ed1 (melanoma).<\/div>\n
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Theo \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc \u1edf Vi\u1ec7n Nghi\u00ean c\u1ee9u Scripps \u0111\u00e3 ph\u00e1t tri\u1ec3n th\u00e0nh c\u00f4ng m\u1ed9t lo\u1ea1i v\u1eafc-xin m\u1edbi \u2013 m\u00e0 khi k\u1ebft h\u1ee3p v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p hi\u1ec7n c\u00f3 \u2013 s\u1ebd cho hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb 100%, kh\u00f4ng ch\u1ec9 ti\u00eau di\u1ec7t kh\u1ed1i u h\u1eafc t\u1ed1 m\u00e0 c\u00f2n ng\u0103n ch\u1eb7n n\u00f3 t\u00e1i ph\u00e1t.<\/p>\n

Theo Gi\u00e1o s\u01b0 Dale Boger, ng\u01b0\u1eddi \u0111\u1ed3ng d\u1eabn \u0111\u1ea7u nghi\u00ean c\u1ee9u v\u1edbi nh\u00e0 khoa h\u1ecdc \u0111o\u1ea1t gi\u1ea3i Nobel Bruce Beutler: “Li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p n\u00e0y cung c\u1ea5p m\u1ed9t \u0111\u00e1p \u1ee9ng ho\u00e0n to\u00e0n – m\u1ed9t \u0111\u00e1p \u1ee9ng c\u00f3 th\u1ec3 ch\u1eefa kh\u1ecfi- trong \u0111i\u1ec1u tr\u1ecb u h\u1eafc t\u1ed1<\/i>“.<\/p>\n

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\"M\u1ed9t<\/div>\n
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“Li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p n\u00e0y cung c\u1ea5p m\u1ed9t \u0111\u00e1p \u1ee9ng ho\u00e0n to\u00e0n – m\u1ed9t \u0111\u00e1p \u1ee9ng c\u00f3 th\u1ec3 ch\u1eefa kh\u1ecfi- trong \u0111i\u1ec1u tr\u1ecb u h\u1eafc t\u1ed1”- gi\u00e1o s\u01b0 Dale Boger<\/p>\n<\/div>\n<\/div>\n

100% nh\u1eefng con chu\u1ed9t \u0111\u00e3 s\u1ed1ng<\/b><\/p>\n

V\u1eafc-xin m\u1edbi \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean chu\u1ed9t. Trong \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u01b0a ra 3 l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb kh\u00e1c nhau cho 3 nh\u00f3m chu\u1ed9t m\u1eafc ung th\u01b0 h\u1eafc t\u1ed1.<\/p>\n

C\u1ea3 3 nh\u00f3m \u0111\u1ec1u \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng m\u1ed9t li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch ung th\u01b0 g\u1ecdi l\u00e0 anti-PD-L1. Nh\u01b0ng nh\u00f3m th\u1ee9 nh\u1ea5t s\u1ebd \u0111\u01b0\u1ee3c ti\u00eam th\u00eam v\u1eafc-xin. Nh\u00f3m th\u1ee9 2 \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc-xin k\u1ebft h\u1ee3p v\u1edbi m\u1ed9t ph\u00e2n t\u1eed g\u1ecdi l\u00e0 Diprovocim. Nh\u00f3m th\u1ee9 3 \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc-xin c\u00f9ng m\u1ed9t t\u00e1 d\u01b0\u1ee3c.<\/p>\n

Diprovocim l\u00e0 m\u1ed9t ch\u1ea5t b\u1ed5 tr\u1ee3 gi\u00fap t\u0103ng c\u01b0\u1eddng \u0111i\u1ec1u tr\u1ecb ung th\u01b0 qua \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch. H\u1ee3p ch\u1ea5t n\u00e0y \u0111ang nh\u1eadn \u0111\u01b0\u1ee3c r\u1ea5t nhi\u1ec1u s\u1ef1 quan t\u00e2m \u0111\u1eb7c bi\u1ec7t c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc, b\u1edfi v\u00ec t\u1ed5ng h\u1ee3p v\u00e0 tinh ch\u1ec9nh n\u00f3 r\u1ea5t d\u1ec5 d\u00e0ng.<\/p>\n

Trong nghi\u00ean c\u1ee9u c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc \u1edf Vi\u1ec7n Scripps, h\u1ecd ph\u00e1t hi\u1ec7n 8 con chu\u1ed9t \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee7ng ng\u1eeba v\u1eafc-xin c\u00f9ng v\u1edbi Diprovocim v\u00e0 li\u1ec7u ph\u00e1p anti-PD-L1 c\u00f3 t\u1ef7 l\u1ec7 s\u1ed1ng \u0111\u1ea1t 100% trong 54 ng\u00e0y.<\/p>\n

Trong khi \u0111\u00f3, nh\u1eefng con chu\u1ed9t ch\u1ec9 \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc-xin c\u00f9ng v\u1edbi anti-PD-L1 \u0111\u1ec1u t\u1eed vong. Nh\u00f3m chu\u1ed9t th\u1ee9 3 nh\u1eadn \u0111\u01b0\u1ee3c anti-PD-L1, ti\u00eam v\u1eafc-xin v\u1edbi t\u00e1 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ea1t t\u1ef7 l\u1ec7 s\u1ed1ng 25%.<\/p>\n

“Th\u1eadt th\u00fa v\u1ecb khi th\u1ea5y thu\u1ed1c ch\u1ee7ng n\u00e0y ho\u1ea1t \u0111\u1ed9ng \u0111\u1ed3ng th\u1eddi v\u1edbi li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch ung th\u01b0 anti-PD-L1<\/i>“, Gi\u00e1o s\u01b0 Boger n\u00f3i.<\/p>\n

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\"M\u1ed9t<\/div>\n
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Diprovocim l\u00e0 m\u1ed9t ch\u1ea5t b\u1ed5 tr\u1ee3 gi\u00fap t\u0103ng c\u01b0\u1eddng \u0111i\u1ec1u tr\u1ecb ung th\u01b0 qua \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch<\/p>\n<\/div>\n<\/div>\n

V\u1eafc-xin c\u0169ng ng\u0103n ng\u1eeba ung th\u01b0 t\u00e1i ph\u00e1t<\/b><\/p>\n

Tuy nhi\u00ean, \u0111i\u1ec1u n\u00e0y kh\u00f4ng ph\u1ea3i l\u00e0 l\u00fd do duy nh\u1ea5t khi\u1ebfn c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u1ea5n kh\u00edch. Th\u1ef1c t\u1ebf, v\u1eafc-xin th\u1eed nghi\u1ec7m c\u00f2n c\u00f3 m\u1ed9t t\u00e1c d\u1ee5ng t\u00edch c\u1ef1c kh\u00e1c n\u1eefa – c\u1ee5 th\u1ec3, n\u00f3 b\u1ea3o v\u1ec7 c\u01a1 th\u1ec3 nh\u1eefng con chu\u1ed9t v\u00e0 ch\u1ed1ng ung th\u01b0 t\u00e1i ph\u00e1t.<\/p>\n

“C\u0169ng gi\u1ed1ng nh\u01b0 m\u1ed9t lo\u1ea1i v\u1eafc-xin c\u00f3 th\u1ec3 \u0111\u00e0o t\u1ea1o c\u01a1 th\u1ec3 \u0111\u1ec3 ch\u1ed1ng l\u1ea1i c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh b\u00ean ngo\u00e0i, v\u1eafc-xin n\u00e0y \u0111\u00e0o t\u1ea1o h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch \u0111\u1ec3 ch\u1ed1ng kh\u1ed1i u quay l\u1ea1i<\/i>“, Gi\u00e1o s\u01b0 Boger n\u00f3i.<\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t hi\u1ec7n ra, khi h\u1ecd c\u1ed1 g\u1eafng k\u00edch ho\u1ea1t c\u00e1c kh\u1ed1i u h\u1eafc t\u1ed1 m\u1edbi \u1edf nh\u1eefng con chu\u1ed9t trong nh\u00f3m th\u1eed nghi\u1ec7m th\u1ee9 hai, “n\u00f3 \u0111\u1ec1u kh\u00f4ng th\u00e0nh c\u00f4ng<\/i>“, Gi\u00e1o s\u01b0 Boger n\u00f3i. “Nh\u1eefng con chu\u1ed9t \u0111\u00e3 \u0111\u01b0\u1ee3c ti\u00eam ph\u00f2ng ch\u1ed1ng l\u1ea1i n\u00f3<\/i>“, \u00f4ng gi\u1ea3i th\u00edch th\u00eam.<\/p>\n

C\u00e1c th\u00ed nghi\u1ec7m ti\u1ebfp theo \u0111\u00e3 ti\u1ebft l\u1ed9 c\u01a1 ch\u1ebf tuy\u1ec7t v\u1eddi ph\u00eda sau li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh r\u1eb1ng Diprovocim l\u00e0m t\u0103ng ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch b\u1eb1ng c\u00e1ch “th\u00fac \u0111\u1ea9y<\/i>” h\u1ec7 mi\u1ec5n d\u1ecbch s\u1ea3n xu\u1ea5t b\u1ea1ch c\u1ea7u th\u00e2m nh\u1eadp v\u00e0o kh\u1ed1i u. C\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u sau \u0111\u00f3 \u0111\u00e3 c\u00f3 th\u1ec3 t\u1ea5n c\u00f4ng v\u00e0 lo\u1ea1i b\u1ecf ung th\u01b0.<\/p>\n

Gi\u00e1o s\u01b0 Boger v\u00e0 nh\u00f3m nghi\u00ean c\u1ee9u c\u0169ng l\u01b0u \u00fd r\u1eb1ng, v\u1eafc-xin k\u1ebft h\u1ee3p v\u1edbi Diprovocim c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n ph\u1ed1i kh\u00e1 d\u1ec5 d\u00e0ng, v\u00ec ch\u00fang kh\u00f4ng c\u1ea7n ph\u1ea3i ti\u00eam tr\u1ef1c ti\u1ebfp v\u00e0o kh\u1ed1i u ung th\u01b0 \u0111\u1ec3 c\u00f3 hi\u1ec7u qu\u1ea3.<\/p>\n

Thay v\u00e0o \u0111\u00f3, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ti\u00eam b\u1eafp nh\u01b0 b\u00ecnh th\u01b0\u1eddng v\u00e0 ch\u1ec9 c\u1ea7n ti\u00eam 2 m\u0169i c\u00e1ch nhau 7 ng\u00e0y.<\/p>\n

Trong giai \u0111o\u1ea1n t\u1edbi, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u s\u1ebd ti\u1ebfp t\u1ee5c th\u1eed nghi\u1ec7m ti\u1ec1n l\u00e2m s\u00e0ng lo\u1ea1i v\u1eafc-xin m\u1edbi n\u00e0y, \u0111\u1ed3ng th\u1eddi ki\u1ec3m tra hi\u1ec7u qu\u1ea3 c\u1ee7a n\u00f3 khi k\u1ebft h\u1ee3p v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p ch\u1eefa tr\u1ecb ung th\u01b0 kh\u00e1c.<\/p>\n

Tham kh\u1ea3o\u00a0Theverger, Medicalnewstoday<\/i><\/p>\n

B\u00c1O \u0110I\u1ec6N T\u1eec TR\u00cd TH\u1ee8C TR\u1eba<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

“Li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p n\u00e0y cung c\u1ea5p m\u1ed9t \u0111\u00e1p \u1ee9ng ho\u00e0n to\u00e0n – m\u1ed9t \u0111\u00e1p \u1ee9ng c\u00f3 th\u1ec3 ch\u1eefa kh\u1ecfi- trong \u0111i\u1ec1u tr\u1ecb u h\u1eafc t\u1ed1”. M\u1ed9t nghi\u00ean c\u1ee9u v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 trong K\u1ef7 y\u1ebfu Vi\u1ec7n H\u00e0n l\u00e2m Khoa h\u1ecdc Hoa K\u1ef3 (PNAS) s\u1ebd mang \u0111\u1ebfn tin vui cho c\u00e1c b\u1ec7nh nh\u00e2n ung th\u01b0 […]<\/p>\n","protected":false},"author":18,"featured_media":13904,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-13903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13903","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=13903"}],"version-history":[{"count":2,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13903\/revisions"}],"predecessor-version":[{"id":13906,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13903\/revisions\/13906"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/13904"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=13903"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=13903"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=13903"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}