{"id":13900,"date":"2018-09-17T08:29:36","date_gmt":"2018-09-17T01:29:36","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=13900"},"modified":"2018-09-17T08:29:36","modified_gmt":"2018-09-17T01:29:36","slug":"cac-nha-khoa-hoc-dang-phai-ket-hop-4-5-loai-khang-sinh-moi-mong-diet-duoc-vi-khuan","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/cac-nha-khoa-hoc-dang-phai-ket-hop-4-5-loai-khang-sinh-moi-mong-diet-duoc-vi-khuan\/","title":{"rendered":"C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111ang ph\u1ea3i k\u1ebft h\u1ee3p 4-5 lo\u1ea1i kh\u00e1ng sinh m\u1edbi mong di\u1ec7t \u0111\u01b0\u1ee3c vi khu\u1ea9n"},"content":{"rendered":"
Kh\u00f4ng bi\u1ebft \u0111\u00e2y l\u00e0 m\u1ed9t tin vui hay tin bu\u1ed3n: Khi c\u00e1c nh\u00e0 khoa h\u1ecdc tr\u1ed9n nh\u1eefng h\u1ed7n h\u1ee3p ch\u1ee9a 4-5 lo\u1ea1i kh\u00e1ng sinh v\u00e0o v\u1edbi nhau, h\u1ecd t\u00ecm \u0111\u01b0\u1ee3c t\u1ed5ng c\u1ed9ng h\u01a1n 8.000 h\u1ed7n h\u1ee3p c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c ti\u00eau di\u1ec7t vi khu\u1ea9n.<\/div>\n
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\u0110\u00f3 l\u00e0 m\u1ed9t tin vui gi\u1eefa b\u1ed1i c\u1ea3nh kh\u00e1ng kh\u00e1ng sinh \u0111ang khi\u1ebfn r\u1ea5t nhi\u1ec1u lo\u1ea1i thu\u1ed1c ri\u00eang l\u1ebb tr\u1edf n\u00ean v\u00f4 d\u1ee5ng. Nh\u01b0ng tr\u00ean m\u1ed9t g\u00f3c nh\u00ecn kh\u00e1c, k\u1ebft h\u1ee3p nhi\u1ec1u lo\u1ea1i kh\u00e1ng sinh cho th\u1ea5y ch\u00fang ta \u0111ang \u0111i v\u00e0o “\u0111\u01b0\u1eddng c\u00f9ng<\/i>” \u0111\u1ec3 gi\u1ea3i quy\u1ebft cu\u1ed9c kh\u1ee7ng ho\u1ea3ng.<\/p>\n

Khi kh\u00f4ng t\u00ecm ra \u0111\u01b0\u1ee3c kh\u00e1ng sinh m\u1edbi, c\u00e1c nh\u00e0 khoa h\u1ecdc m\u1edbi ph\u1ea3i k\u1ebft h\u1ee3p nhi\u1ec1u lo\u1ea1i kh\u00e1ng sinh c\u0169 v\u1edbi nhau. Tr\u01b0\u1edbc \u0111\u00e2y, ch\u00ednh h\u1ecd \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh ph\u01b0\u01a1ng ph\u00e1p n\u00e0y cho hi\u1ec7u qu\u1ea3 r\u1ea5t h\u1ea1n ch\u1ebf. Vi\u1ec7c tr\u1ed9n nhi\u1ec1u lo\u1ea1i kh\u00e1ng sinh c\u00f3 th\u1ec3 khi\u1ebfn c\u00e1c lo\u1ea1i thu\u1ed1c t\u1ef1 tri\u1ec7t ti\u00eau nhau.<\/p>\n

Ngay c\u1ea3 khi \u0111i\u1ec1u \u0111\u00f3 kh\u00f4ng x\u1ea3y ra, hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i nhi\u1ec5m tr\u00f9ng c\u1ee7a lo\u1ea1i thu\u1ed1c k\u1ebft h\u1ee3p c\u0169ng kh\u00f4ng t\u0103ng l\u00ean l\u00e0 bao, v\u00e0 n\u00f3 th\u1eadm ch\u00ed c\u00f2n l\u00e0m cho vi khu\u1ea9n kh\u00e1ng kh\u00e1ng sinh m\u1ea1nh h\u01a1n n\u1eefa.<\/p>\n

V\u1eady v\u00ec l\u00fd do g\u00ec m\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc b\u00e2y gi\u1edd ph\u1ea3i tr\u1ed9n \u0111\u1ebfn 4-5 lo\u1ea1i thu\u1ed1c c\u00f9ng l\u00fac?<\/p>\n

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\"C\u00e1c<\/div>\n
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C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111ang ph\u1ea3i tr\u1ed9n 4-5 lo\u1ea1i kh\u00e1ng sinh v\u1edbi nhau \u0111\u1ec3 t\u00ecm c\u00e1ch ti\u00eau di\u1ec7t vi khu\u1ea9n<\/p>\n<\/div>\n<\/div>\n

Nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c nh\u00e0 sinh v\u1eadt h\u1ecdc t\u1eeb \u0110\u1ea1i h\u1ecdc California \u1edf Los Angeles (UCLA). Trong \u0111\u00f3, h\u1ecd \u0111\u00e3 s\u1eed d\u1ee5ng m\u1ed9t h\u1ec7 th\u1ed1ng th\u1eed nghi\u1ec7m \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh h\u00e0ng ng\u00e0n h\u1ed7n h\u1ee3p thu\u1ed1c m\u1edbi, k\u1ebft h\u1ee3p t\u1eeb 4-5 lo\u1ea1i kh\u00e1ng sinh \u1edf c\u00e1c li\u1ec1u kh\u00e1c nhau.<\/p>\n

M\u1eb7c d\u00f9 m\u1edbi ch\u1ec9 l\u00e0 th\u1eed nghi\u1ec7m, k\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u n\u00e0y h\u1ee9a h\u1eb9n s\u1ebd cho ph\u00e9p ch\u00fang ta k\u00e9o d\u00e0i cu\u1ed9c gi\u1eb1ng co v\u1edbi vi khu\u1ea9n kh\u00e1ng kh\u00e1ng sinh. \u1ede th\u1eddi \u0111i\u1ec3m hi\u1ec7n t\u1ea1i, m\u1ed9t s\u1ed1 vi khu\u1ea9n \u0111\u00e3 ch\u1ed1ng l\u1ea1i \u0111\u01b0\u1ee3c t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i thu\u1ed1c con ng\u01b0\u1eddi hi\u1ec7n c\u00f3.<\/p>\n

“Truy\u1ec1n th\u1ed1ng [trong \u0111i\u1ec1u tr\u1ecb hi\u1ec7n nay] ch\u1ec9 s\u1eed d\u1ee5ng m\u1ed9t ho\u1eb7c 2 lo\u1ea1i kh\u00e1ng sinh<\/i>“, Pamela Yeh, m\u1ed9t trong nh\u1eefng t\u00e1c gi\u1ea3 c\u1ee7a nghi\u00ean c\u1ee9u n\u00f3i. “Ch\u00fang t\u00f4i \u0111ang cung c\u1ea5p m\u1ed9t gi\u1ea3i ph\u00e1p thay th\u1ebf r\u1ea5t h\u1ee9a h\u1eb9n”.<\/i><\/p>\n

“Ch\u00fang ta kh\u00f4ng n\u00ean gi\u1edbi h\u1ea1n b\u1ea3n th\u00e2n ch\u1ec9 d\u00f9ng m\u1ed9t lo\u1ea1i thu\u1ed1c ho\u1eb7c k\u1ebft h\u1ee3p hai lo\u1ea1i thu\u1ed1c trong h\u1ed9p y t\u1ebf c\u1ee7a ch\u00fang ta. Ch\u00fang t\u00f4i tr\u00f4ng \u0111\u1ee3i m\u1ed9t v\u00e0i lo\u1ea1i thu\u1ed1c k\u1ebft h\u1ee3p [gi\u1eefa 4-5 kh\u00e1ng sinh] n\u00e0y, ho\u1eb7c nhi\u1ec1u h\u01a1n n\u1eefa, s\u1ebd ho\u1ea1t \u0111\u1ed9ng hi\u1ec7u qu\u1ea3 h\u01a1n nhi\u1ec1u so v\u1edbi t\u1eebng lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh ri\u00eang l\u1ebb hi\u1ec7n c\u00f3”.<\/i><\/p>\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u1eaft \u0111\u1ea7u th\u1eed nghi\u1ec7m c\u1ee7a m\u00ecnh v\u1edbi 8 lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh \u0111\u1ec3 t\u1ea1o th\u00e0nh nh\u1eefng t\u1ed5 h\u1ee3p m\u1ed7i 4-5 lo\u1ea1i thu\u1ed1c k\u1ebft h\u1ee3p theo li\u1ec1u l\u01b0\u1ee3ng. Ch\u00fang \u0111\u01b0\u1ee3c ki\u1ec3m tra hi\u1ec7u qu\u1ea3 trong vi\u1ec7c ch\u1ed1ng l\u1ea1i vi khu\u1ea9n Escherichia coli.<\/p>\n

T\u1ed5ng c\u1ed9ng, h\u1ecd \u0111\u00e3 th\u1eed nghi\u1ec7m 18.278 t\u1ed5 h\u1ee3p thu\u1ed1c, bao g\u1ed3m c\u00e1c li\u1ec1u kh\u00e1c nhau c\u1ee7a m\u1ed7i lo\u1ea1i thu\u1ed1c th\u00e0nh ph\u1ea7n.<\/p>\n

Trong danh s\u00e1ch k\u1ebft h\u1ee3p b\u1ed1n lo\u1ea1i thu\u1ed1c, 1.676 t\u1ed5 h\u1ee3p cho k\u1ebft qu\u1ea3 ngo\u00e0i d\u1ef1 ki\u1ebfn; t\u1ed5ng c\u1ed9ng 6.443 t\u1ed5 h\u1ee3p c\u1ee7a 5 lo\u1ea1i kh\u00e1ng sinh c\u0169ng ti\u00eau di\u1ec7t E. coli hi\u1ec7u qu\u1ea3.<\/p>\n

Nh\u01b0ng ng\u01b0\u1ee3c l\u1ea1i, 2.331 t\u1ed5 h\u1ee3p 4 lo\u1ea1i thu\u1ed1c v\u00e0 5.199 t\u1ed5 h\u1ee3p 5 lo\u1ea1i thu\u1ed1c kh\u00e1c \u0111\u00e3 t\u1ecf ra k\u00e9m hi\u1ec7u qu\u1ea3 h\u01a1n trong vi\u1ec7c ch\u1ed1ng l\u1ea1i nhi\u1ec5m tr\u00f9ng, so v\u1edbi m\u1ee9c c\u00e1c nh\u00e0 khoa h\u1ecdc mong \u0111\u1ee3i.<\/p>\n

“T\u00f4i b\u1ecb th\u1ed5i bay b\u1edfi con s\u1ed1 t\u1ed5 h\u1ee3p kh\u00e1ng sinh c\u00f3 hi\u1ec7u qu\u1ea3 khi ch\u00fang t\u00f4i t\u0103ng s\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c k\u1ebft h\u1ee3p<\/i>“, Van Savage, m\u1ed9t nh\u00e0 nghi\u00ean c\u1ee9u kh\u00e1c trong nh\u00f3m cho bi\u1ebft. “M\u1ecdi ng\u01b0\u1eddi c\u00f3 th\u1ec3 ngh\u0129 r\u1eb1ng k\u1ebft h\u1ee3p thu\u1ed1c s\u1ebd g\u00e2y ra s\u1ef1 t\u01b0\u01a1ng t\u00e1c [l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3], nh\u01b0ng ch\u00fang th\u1ef1c s\u1ef1 kh\u00f4ng g\u00e2y ra \u0111i\u1ec1u \u0111\u00f3”.<\/i><\/p>\n

M\u1ed9t ph\u1ea7n l\u00fd do, c\u00e1c nh\u00e0 khoa h\u1ecdc ngh\u0129 l\u00e0 c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c nhau t\u1ea5n c\u00f4ng vi khu\u1ea9n theo nhi\u1ec1u c\u00e1ch kh\u00e1c nhau. T\u00e1m lo\u1ea1i thu\u1ed1c m\u00e0 h\u1ecd \u0111\u00e3 ch\u1ecdn c\u00f3 6 c\u01a1 ch\u1ebf kh\u00e1c nhau \u0111\u1ec3 ch\u1ed1ng l\u1ea1i vi khu\u1ea9n E. coli, v\u00e0 trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p, k\u1ebft h\u1ee3p nhi\u1ec1u v\u0169 kh\u00ed c\u00f3 v\u1ebb hi\u1ec7u qu\u1ea3 h\u01a1n m\u1ed9t 1 v\u0169 kh\u00ed duy nh\u1ea5t.<\/p>\n

“M\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c t\u1ea5n c\u00f4ng th\u00e0nh t\u1ebf b\u00e0o, nh\u1eefng thu\u1ed1c kh\u00e1c t\u1ea5n c\u00f4ng DNA b\u00ean trong<\/i>“, Savage n\u00f3i. “N\u00f3 gi\u1ed1ng nh\u01b0 chi\u1ebfn thu\u1eadt t\u1ea5n c\u00f4ng m\u1ed9t l\u00e2u \u0111\u00e0i hay ph\u00e1o \u0111\u00e0i”.<\/i><\/p>\n

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\"C\u00e1c<\/div>\n
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S\u01a1 \u0111\u1ed3 cho th\u1ea5y c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111ang ph\u1ea3i k\u1ebft h\u1ee3p t\u1eeb 4-5 lo\u1ea1i kh\u00e1ng sinh v\u1edbi nhau<\/p>\n<\/div>\n<\/div>\n

M\u1eb7c d\u00f9 hi\u1ec7u qu\u1ea3 c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh b\u01b0\u1edbc \u0111\u1ea7u, trong m\u00f4i tr\u01b0\u1eddng ph\u00f2ng th\u00ed nghi\u1ec7m v\u00e0 tr\u00ean khu\u1ea9n E. coli, ch\u00fang ta s\u1ebd ph\u1ea3i h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng v\u1edbi \u00fd t\u01b0\u1edfng \u0111\u00f3. C\u00e1c lo\u1ea1i thu\u1ed1c ph\u1ea3i \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn r\u1ea5t c\u1ea9n th\u1eadn, v\u00e0 c\u00e1c th\u1eed nghi\u1ec7m s\u1ebd c\u00f2n ph\u1ea3i ti\u1ebfn h\u00e0nh th\u00eam \u00edt nh\u1ea5t v\u00e0i n\u0103m n\u1eefa.<\/p>\n

Ngo\u00e0i ra, nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y \u0111\u00e3 ph\u00e1t hi\u1ec7n vi\u1ec7c s\u1eed d\u1ee5ng nhi\u1ec1u lo\u1ea1i kh\u00e1ng sinh c\u00f9ng m\u1ed9t l\u00fac c\u00f3 th\u1ec3 ph\u1ea3n t\u00e1c d\u1ee5ng, l\u00e0m cho vi khu\u1ea9n th\u1eadm ch\u00ed c\u00f2n kh\u00e1ng kh\u00e1ng sinh m\u1ea1nh h\u01a1n. \u0110\u00e2y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 m\u1ed9t h\u01b0\u1edbng ti\u1ebfp c\u1eadn “\u0111\u01b0\u1eddng c\u00f9ng<\/i>“.<\/p>\n

Nh\u01b0ng r\u00f5 r\u00e0ng, cu\u1ed9c kh\u1ee7ng ho\u1ea3ng kh\u00e1ng kh\u00e1ng sinh hi\u1ec7n nay \u0111\u00e3 \u0111\u01b0a ch\u00fang ta v\u00e0o th\u1ebf ph\u1ea3i l\u00e0m b\u1ea5t c\u1ee9 \u0111i\u1ec1u g\u00ec c\u00f3 th\u1ec3. C\u00e1c t\u1ed5 ch\u1ee9c y t\u1ebf tr\u00ean to\u00e0n th\u1ebf gi\u1edbi v\u1eabn \u0111ang ti\u1ebfp t\u1ee5c c\u1ea3nh b\u00e1o v\u1ec1 m\u1ed1i \u0111e d\u1ecda nghi\u00eam tr\u1ecdng c\u1ee7a kh\u00e1ng kh\u00e1ng sinh. N\u1ebfu ch\u00fang ta kh\u00f4ng th\u1ec3 t\u00ecm ra c\u00e1c bi\u1ec7n ph\u00e1p m\u1edbi \u0111\u1ec3 ti\u00eau di\u1ec7t vi khu\u1ea9n, ch\u00fang c\u00f3 th\u1ec3 g\u00e2y ra 10 tri\u1ec7u c\u00e1i ch\u1ebft m\u1ed7i n\u0103m v\u00e0o gi\u1eefa th\u1ec3 k\u1ef7 n\u00e0y.<\/p>\n

Michael Kurilla, gi\u00e1m \u0111\u1ed1c b\u1ed9 ph\u1eadn \u0111\u1ed5i m\u1edbi l\u00e2m s\u00e0ng t\u1ea1i Vi\u1ec7n Y t\u1ebf Qu\u1ed1c gia Hoa K\u1ef3, cho bi\u1ebft nghi\u00ean c\u1ee9u m\u1edbi n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m n\u1ec1n t\u1ea3ng cho c\u00e1c nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n h\u01b0\u1edbng \u0111\u1ebfn vi\u1ec7c k\u1ebft h\u1ee3p \u0111a kh\u00e1ng sinh.<\/p>\n

“Kh\u00e1ng kh\u00e1ng sinh \u0111ang \u0111e d\u1ecda \u0111\u1ea9y n\u1ec1n y t\u1ebf c\u1ee7a ch\u00fang ta tr\u1edf l\u1ea1i th\u1eddi k\u1ef3 ti\u1ec1n kh\u00e1ng sinh. V\u00ec v\u1eady, k\u1ebft h\u1ee3p c\u00e1c lo\u1ea1i kh\u00e1ng sinh hi\u1ec7n c\u00f3, m\u1ed9t c\u00e1ch th\u1eadn tr\u1ecdng thay cho t\u1eebng lo\u1ea1i kh\u00e1ng sinh ri\u00eang l\u1ebb \u0111\u00e3 m\u1ea5t t\u00e1c d\u1ee5ng, l\u00e0 m\u1ed9t h\u01b0\u1edbng ti\u1ebfp c\u1eadn \u0111\u01b0\u1ee3c hoan ng\u00eanh<\/i>“, Kurilla n\u00f3i.<\/p>\n

Nghi\u00ean c\u1ee9u m\u1edbi n\u00e0y v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Systems Biology and Applications.<\/p>\n

Tham kh\u1ea3o\u00a0ScienceAlert<\/i><\/p>\n

B\u00c1O \u0110I\u1ec6N T\u1eec TR\u00cd TH\u1ee8C TR\u1eba<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Kh\u00f4ng bi\u1ebft \u0111\u00e2y l\u00e0 m\u1ed9t tin vui hay tin bu\u1ed3n: Khi c\u00e1c nh\u00e0 khoa h\u1ecdc tr\u1ed9n nh\u1eefng h\u1ed7n h\u1ee3p ch\u1ee9a 4-5 lo\u1ea1i kh\u00e1ng sinh v\u00e0o v\u1edbi nhau, h\u1ecd t\u00ecm \u0111\u01b0\u1ee3c t\u1ed5ng c\u1ed9ng h\u01a1n 8.000 h\u1ed7n h\u1ee3p c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c ti\u00eau di\u1ec7t vi khu\u1ea9n. \u0110\u00f3 l\u00e0 m\u1ed9t tin vui gi\u1eefa b\u1ed1i c\u1ea3nh kh\u00e1ng kh\u00e1ng […]<\/p>\n","protected":false},"author":18,"featured_media":13901,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-13900","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=13900"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13900\/revisions"}],"predecessor-version":[{"id":13902,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13900\/revisions\/13902"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/13901"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=13900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=13900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=13900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}