{"id":13109,"date":"2018-07-25T16:16:08","date_gmt":"2018-07-25T09:16:08","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=13109"},"modified":"2018-08-10T16:36:17","modified_gmt":"2018-08-10T09:36:17","slug":"vi-khuan-vo-hai-trong-ruot-bien-thanh-dang-an-thit-nguoi-giet-chet-5-benh-nhan-trung-quoc-tu-dau-nam-toi-nay","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/vi-khuan-vo-hai-trong-ruot-bien-thanh-dang-an-thit-nguoi-giet-chet-5-benh-nhan-trung-quoc-tu-dau-nam-toi-nay\/","title":{"rendered":"Vi khu\u1ea9n v\u00f4 h\u1ea1i trong ru\u1ed9t bi\u1ebfn th\u00e0nh d\u1ea1ng \u0103n th\u1ecbt ng\u01b0\u1eddi, gi\u1ebft ch\u1ebft 5 b\u1ec7nh nh\u00e2n Trung Qu\u1ed1c t\u1eeb \u0111\u1ea7u n\u0103m t\u1edbi nay"},"content":{"rendered":"

Nh\u1eefng con hvKp hay xu\u1ea5t hi\u1ec7n \u1edf c\u00e1c qu\u1ed1c gia Ch\u00e2u \u00c1, kh\u00f4ng r\u00f5 v\u00ec ch\u00fang b\u1eaft \u0111\u1ea7u l\u00e2y lan t\u1eeb \u0111\u00e2y hay v\u00ec nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi ng\u01b0\u1eddi da v\u00e0ng.<\/p>\n

\u0110\u01b0\u1eddng ru\u1ed9t c\u1ee7a b\u1ea1n l\u00e0 ng\u00f4i nh\u00e0 cho h\u00e0ng t\u1ef7 vi khu\u1ea9n, l\u1ee3i c\u00f3 h\u1ea1i c\u00f3. M\u1ed9t trong s\u1ed1 nh\u1eefng lo\u00e0i vi khu\u1ea9n kh\u00e1 l\u00e0nh t\u00ednh s\u1ed1ng trong ru\u1ed9t l\u00e0 Klebsiella pneumoniae. Ch\u00fang tr\u00f4i d\u1ea1t m\u1ed9t c\u00e1ch v\u00f4 h\u1ea1i trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u00f4i khi xu\u1ea5t hi\u1ec7n c\u1ea3 tr\u00ean khoang mi\u1ec7ng v\u00e0 b\u00ean ngo\u00e0i da.<\/div>\n
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Klebsiella pneumoniae th\u1eadm ch\u00ed c\u00f2n c\u00f3 l\u1ee3i trong vi\u1ec7c \u1ee9c ch\u1ebf s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c vi khu\u1ea9n g\u00e2y h\u1ea1i kh\u00e1c. Ch\u1ec9 c\u00f3 \u0111i\u1ec1u, m\u1ed9t khi n\u00f3 bi\u1ebfn th\u00e0nh d\u1ea1ng si\u00eau vi khu\u1ea9n (hypervirulent strain of K. pneumoniae \u2013hvKp), b\u1ea1n s\u1ebd ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi m\u1ed9t c\u01a1n \u00e1c m\u1ed9ng th\u1ef1c s\u1ef1.<\/p>\n

N\u0103m 1980, c\u00e1c b\u00e1c s\u0129 t\u1ea1i \u0110\u00e0i Loan ph\u00e1t hi\u1ec7n ra ch\u1ee7ng hvKp c\u00f3 th\u1ec3 g\u00e2y nhi\u1ec5m tr\u00f9ng d\u1eabn \u0111\u1ebfn \u00e1p xe n\u00e3o v\u00e0 gan. hvKp c\u0169ng \u0111\u00f3ng vai m\u1ed9t d\u1ea1ng vi khu\u1ea9n \u0103n th\u1ecbt ng\u01b0\u1eddi g\u00e2y ho\u1ea1i t\u1eed t\u1eeb b\u00ean trong. N\u00f3 c\u00f3 th\u1ec3 gi\u1ebft ch\u1ebft m\u1ed9t ng\u01b0\u1eddi ho\u00e0n to\u00e0n kh\u1ecfe m\u1ea1nh ch\u1ec9 trong v\u00f2ng 1 ng\u00e0y.<\/p>\n

\u0110i\u1ec1u \u0111\u00e1ng n\u00f3i n\u1eb1m \u1edf ch\u1ed7, ch\u00fang ta ch\u01b0a c\u00f3 b\u1ea5t c\u1ee9 c\u00e1ch n\u00e0o \u0111\u1ec3 ph\u00e2n bi\u1ec7t \u0111\u01b0\u1ee3c Klebsiella pneumoniae d\u1ea1ng th\u01b0\u1eddng v\u00e0 d\u1ea1ng si\u00eau vi khu\u1ea9n hvKp. C\u00e1c b\u00e1c s\u0129 ch\u1ec9 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c hvKp khi c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u00e3 x\u1ea3y ra tr\u00ean ng\u01b0\u1eddi b\u1ec7nh, th\u01b0\u1eddng th\u00ec khi \u0111\u00f3 \u0111\u00e3 qu\u00e1 mu\u1ed9n.<\/p>\n

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\"Vi<\/div>\n
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Khi vi khu\u1ea9n v\u00f4 h\u1ea1i trong ru\u1ed9t bi\u1ebfn th\u00e0nh d\u1ea1ng \u0103n th\u1ecbt ng\u01b0\u1eddi, n\u00f3 c\u00f3 th\u1ec3 gi\u1ebft ch\u1ebft b\u1ea1n ch\u1ec9 trong v\u00f2ng 1 ng\u00e0y<\/p>\n<\/div>\n<\/div>\n

X\u00e1c \u0111\u1ecbnh s\u1edbm \u0111\u01b0\u1ee3c hvKp v\u00e0 ph\u00e2n bi\u1ec7t n\u00f3 v\u1edbi Klebsiella pneumoniae d\u1ea1ng th\u01b0\u1eddng l\u00e0 m\u1ed9t m\u1ee5c ti\u00eau m\u00e0 nhi\u1ec1u nh\u00e0 khoa h\u1ecdc \u0111\u00e3 theo \u0111u\u1ed5i trong nhi\u1ec1u n\u0103m nay.<\/p>\n

T\u1ea1i \u0110\u1ea1i h\u1ecdc Buffalo \u1edf M\u1ef9, Thomas Russo, tr\u01b0\u1edfng khoa truy\u1ec1n nhi\u1ec5m v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p c\u1ee7a \u00f4ng \u0111\u00e3 t\u00ecm ra \u0111\u01b0\u1ee3c nh\u1eefng th\u1ebb di truy\u1ec1n \u1ea9n k\u00edn trong DNA c\u1ee7a hvKp. Nh\u1eefng th\u1ebb n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 nh\u1eadn di\u1ec7n si\u00eau vi khu\u1ea9n Klebsiella pneumoniae m\u1ed9t c\u00e1ch ch\u00ednh x\u00e1c v\u00e0 \u0111\u00e1ng tin c\u1eady.<\/p>\n

\u201cHi\u1ec7n nay, kh\u00f4ng c\u00f3 b\u1ea5t k\u1ec3 x\u00e9t nghi\u1ec7m ph\u1ed5 th\u00f4ng n\u00e0o \u0111\u1ec3 ph\u00e2n bi\u1ec7t ch\u00ednh x\u00e1c c\u00e1c ch\u1ee7ng Klebsiella pneumoniae b\u00ecnh th\u01b0\u1eddng v\u00e0 hypervirulent<\/i>“, Russo n\u00f3i. “Nghi\u00ean c\u1ee9u n\u00e0y cung c\u1ea5p m\u1ed9t l\u1ed9 tr\u00ecnh r\u00f5 r\u00e0ng v\u1ec1 c\u00e1ch m\u1ed9t c\u00f4ng ty c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n x\u00e9t nghi\u1ec7m nh\u01b0 v\u1eady \u0111\u1ec3 s\u1eed d\u1ee5ng trong c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m l\u00e2m s\u00e0ng. N\u00f3 h\u1ebft s\u1ee9c c\u1ea7n thi\u1ebft”.<\/i><\/p>\n

H\u1ebft s\u1ee9c c\u1ea7n thi\u1ebft th\u1eadt ra c\u0169ng \u0111\u00e3 l\u00e0 m\u1ed9t c\u00e1ch n\u00f3i gi\u1ea3m \u0111i nhi\u1ec1u. V\u00e0i n\u0103m tr\u1edf l\u1ea1i \u0111\u00e2y, c\u00e1c nh\u00e0 b\u1ec7nh h\u1ecdc l\u1ea1i ph\u00e1t hi\u1ec7n ra m\u1ed9t h\u00ecnh th\u1ee9c \u0111a kh\u00e1ng thu\u1ed1c (MDR) c\u1ee7a K. pneumoniae. D\u1ea1ng si\u00eau vi khu\u1ea9n m\u1edbi n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng ch\u1ed1ng l\u1ea1i c\u1ea3 kh\u00e1ng sinh m\u1ea1nh nh\u1ea5t c\u1ee7a ch\u00fang ta.<\/p>\n

Cho \u0111\u1ebfn th\u1eddi \u0111i\u1ec3m n\u00e0y, s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a si\u00eau vi khu\u1ea9n K. pneumoniae kh\u00e1ng kh\u00e1ng sinh v\u1eabn c\u00f2n ch\u01b0a ph\u1ed5 bi\u1ebfn. Nh\u01b0ng t\u1ef7 l\u1ec7 \u0111ang gia t\u0103ng v\u00e0 c\u00e1c t\u1ed5 ch\u1ee9c y t\u1ebf \u0111\u1eb7t s\u1ef1 c\u1ea3nh gi\u00e1c cao \u0111\u1ed9 tr\u00ean n\u00f3. K\u1ecbch b\u1ea3n \u0111\u00e1ng s\u1ee3 l\u00e0 khi hvKp k\u1ebft h\u1ee3p v\u1edbi si\u00eau vi khu\u1ea9n n\u00e0y v\u00e0 h\u1ecdc \u0111\u01b0\u1ee3c kh\u1ea3 n\u0103ng ch\u1ed1ng l\u1ea1i kh\u00e1ng sinh d\u00f2ng cu\u1ed1i c\u00f9ng … ch\u00fang ta s\u1ebd g\u1eb7p r\u1eafc r\u1ed1i to.<\/p>\n

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\"Vi<\/div>\n
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Klebsiella pneumoniae l\u00e0 nh\u1eefng vi khu\u1ea9n s\u1ed1ng trong \u0111\u01b0\u1eddng ru\u1ed9t c\u1ee7a ch\u00fang ta<\/p>\n<\/div>\n<\/div>\n

C\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t, c\u00f3 m\u1ed9t x\u00e9t nghi\u1ec7m \u0111\u1ec3 ph\u00e2n bi\u1ec7t hvKp v\u1edbi vi khu\u1ea9n K. pneumoniae th\u00f4ng th\u01b0\u1eddng s\u1ebd l\u00e0 m\u1ed9t chi\u1ebfn th\u1eafng cho m\u1ed7i b\u1ec7nh nh\u00e2n kh\u00f4ng may nhi\u1ec5m ph\u1ea3i n\u00f3. Tr\u00ean g\u00f3c nh\u00ecn v\u0129 m\u00f4, \u0111\u00f3 s\u1ebd c\u00f2n l\u00e0 c\u00f4ng c\u1ee5 cho c\u00e1c nh\u00e0 d\u1ecbch t\u1ec5 h\u1ecdc theo d\u00f5i s\u1ef1 l\u00e2y lan c\u1ee7a si\u00eau vi khu\u1ea9n, c\u1ea3nh gi\u00e1c s\u1ef1 kh\u00e1ng thu\u1ed1c v\u00e0 b\u00e1o hi\u1ec7u v\u1edbi d\u00e2n ch\u00fang khi c\u1ea7n thi\u1ebft.<\/p>\n

K\u1ecbch b\u1ea3n x\u1ea5u v\u1ec1 K. pneumoniae c\u00f3 th\u1ec3 x\u1ea3y ra theo 2 chi\u1ec1u h\u01b0\u1edbng: M\u1ed9t l\u00e0 nh\u1eefng con hvKp c\u00f3 th\u1ec3 nh\u1eb7t DNA kh\u00e1ng thu\u1ed1c trong m\u00f4i tr\u01b0\u1eddng m\u00e0 nh\u1eefng con K. pneumoniae MDR ch\u1ebft \u0111i \u0111\u1ec3 l\u1ea1i. T\u1eeb \u0111\u00f3, ch\u00fang s\u1ebd h\u1ecdc \u0111\u01b0\u1ee3c c\u00e1ch kh\u00e1ng t\u1ea5t c\u1ea3 c\u00e1c kh\u00e1ng sinh hi\u1ec7n c\u00f3.<\/p>\n

Hai l\u00e0 nh\u1eefng con K. pneumoniae \u0111a kh\u00e1ng thu\u1ed1c c\u00f3 th\u1ec3 bi\u1ebfn h\u00ecnh th\u00e0nh d\u1ea1ng hvKp \u0103n th\u1ecbt ng\u01b0\u1eddi. Th\u1ef1c t\u1ebf th\u00ec k\u1ecbch b\u1ea3n s\u1ed1 2 \u0111\u00e3 x\u1ea3y ra \u0111\u1ea7u n\u0103m nay. \u201cN\u00f3 l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y ra c\u00e1i ch\u1ebft c\u1ee7a 5 b\u1ec7nh nh\u00e2n trong \u0111\u01a1n v\u1ecb ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t c\u1ee7a m\u1ed9t b\u1ec7nh vi\u1ec7n \u1edf H\u00e0ng Ch\u00e2u, Trung Qu\u1ed1c<\/i>\u201d, Russo cho bi\u1ebft.<\/p>\n

Nh\u1eefng con hvKp hay xu\u1ea5t hi\u1ec7n \u1edf c\u00e1c qu\u1ed1c gia Ch\u00e2u \u00c1, kh\u00f4ng r\u00f5 v\u00ec ch\u00fang b\u1eaft \u0111\u1ea7u l\u00e2y lan t\u1eeb \u0111\u00e2y hay v\u00ec nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi ng\u01b0\u1eddi da v\u00e0ng.<\/p>\n

C\u00f2n qu\u00e1 nhi\u1ec1u \u0111i\u1ec1u ch\u00fang ta c\u1ea7n t\u00ecm hi\u1ec3u v\u1ec1 nh\u1eefng con K. pneumoniae v\u00e0 2 d\u1ea1ng si\u00eau vi khu\u1ea9n c\u1ee7a n\u00f3. Hi\u1ec7n t\u1ea1i, \u0111i\u1ec1u m\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u nh\u1eafm \u0111\u1ebfn l\u00e0 ph\u00e2n bi\u1ec7t \u0111\u01b0\u1ee3c m\u1ed9t c\u00e1ch ch\u00ednh x\u00e1c d\u1ea1ng hvKp.<\/p>\n

T\u1ea5t nhi\u00ean, theo d\u00f5i s\u00e1t sao c\u00e1c ch\u1ee7ng si\u00eau vi khu\u1ea9n n\u00e0y l\u00e0 \u0111i\u1ec1u c\u1ea7n thi\u1ebft. B\u00ean c\u1ea1nh \u0111\u00f3, ch\u00fang ta c\u0169ng ph\u1ea3i t\u00ecm ra c\u00e1ch gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 kh\u00e1ng kh\u00e1ng sinh n\u00f3i chung. T\u00ecm ra c\u00e1c lo\u1ea1i kh\u00e1ng sinh m\u1edbi \u0111\u1ec3 ch\u1ed1ng l\u1ea1i K. pneumoniae \u0111a kh\u00e1ng thu\u1ed1c c\u0169ng l\u00e0 m\u1ed9t gi\u1ea3i ph\u00e1p.<\/p>\n

Nghi\u00ean c\u1ee9u v\u1ec1 K. pneumoniae \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Journal of Clinical Microbiology.<\/p>\n

Tham kh\u1ea3o\u00a0Sciencealert<\/i><\/p>\n

B\u00c1O \u0110I\u1ec6N T\u1eec TR\u00cd TH\u1ee8C TR\u1eba<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Nh\u1eefng con hvKp hay xu\u1ea5t hi\u1ec7n \u1edf c\u00e1c qu\u1ed1c gia Ch\u00e2u \u00c1, kh\u00f4ng r\u00f5 v\u00ec ch\u00fang b\u1eaft \u0111\u1ea7u l\u00e2y lan t\u1eeb \u0111\u00e2y hay v\u00ec nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi ng\u01b0\u1eddi da v\u00e0ng. \u0110\u01b0\u1eddng ru\u1ed9t c\u1ee7a b\u1ea1n l\u00e0 ng\u00f4i nh\u00e0 cho h\u00e0ng t\u1ef7 vi khu\u1ea9n, l\u1ee3i c\u00f3 h\u1ea1i c\u00f3. M\u1ed9t trong s\u1ed1 nh\u1eefng lo\u00e0i vi khu\u1ea9n kh\u00e1 […]<\/p>\n","protected":false},"author":18,"featured_media":13110,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-13109","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=13109"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13109\/revisions"}],"predecessor-version":[{"id":13111,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/13109\/revisions\/13111"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/13110"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=13109"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=13109"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=13109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}