{"id":12772,"date":"2018-07-12T13:51:16","date_gmt":"2018-07-12T06:51:16","guid":{"rendered":"https:\/\/ttud.com.vn\/?p=12772"},"modified":"2018-08-06T11:19:44","modified_gmt":"2018-08-06T04:19:44","slug":"cac-bac-si-dieu-tri-ung-thu-bang-cach-tiem-virus-bai-liet-bien-doi-gen-vao-nao-benh-nhan","status":"publish","type":"post","link":"https:\/\/casta.ttud.com.vn\/index.php\/cac-bac-si-dieu-tri-ung-thu-bang-cach-tiem-virus-bai-liet-bien-doi-gen-vao-nao-benh-nhan\/","title":{"rendered":"C\u00e1c b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng c\u00e1ch ti\u00eam virus b\u1ea1i li\u1ec7t bi\u1ebfn \u0111\u1ed5i gen v\u00e0o n\u00e3o b\u1ec7nh nh\u00e2n"},"content":{"rendered":"

B\u1ec7nh nh\u00e2n ung th\u01b0 n\u00e3o d\u1ea1ng Glioblastoma \u0111ang c\u00f3 nhi\u1ec1u c\u01a1 h\u1ed9i h\u01a1n.<\/p>\n

M\u1ed9t b\u00e1o c\u00e1o v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Y h\u1ecdc New England tu\u1ea7n tr\u01b0\u1edbc, cho th\u1ea5y k\u1ebft qu\u1ea3 kh\u1ea3 quan c\u1ee7a m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng, trong \u0111\u00f3, c\u00e1c b\u00e1c s\u0129 \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng nh\u1eefng ca b\u1ec7nh ung th\u01b0 n\u00e3o b\u1eb1ng virus b\u1ea1i li\u1ec7t \u0111\u01b0\u1ee3c bi\u1ebfn \u0111\u1ed5i gen.<\/div>\n
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T\u1ef7 l\u1ec7 s\u1ed1ng tr\u00ean 3 n\u0103m c\u1ee7a c\u00e1c b\u1ec7nh nh\u00e2n ung th\u01b0 n\u00e3o d\u1ea1ng Glioblastoma, hay c\u00f2n g\u1ecdi l\u00e0 kh\u1ed1i u nguy\u00ean b\u00e0o th\u1ea7n kinh \u0111\u1ec7m, \u0111\u00e3 t\u0103ng l\u00ean t\u1edbi 21% trong th\u1eed nghi\u1ec7m. Tr\u01b0\u1edbc \u0111\u00e2y, u nguy\u00ean b\u00e0o th\u1ea7n kinh \u0111\u1ec7m g\u1ea7n nh\u01b0 l\u00e0 b\u1ea3n \u00e1n t\u1eed v\u1edbi ng\u01b0\u1eddi b\u1ec7nh, ch\u1ec9 c\u00f3 4% b\u1ec7nh nh\u00e2n s\u1ed1ng tr\u00ean 3 n\u0103m.<\/p>\n

Ph\u1eabu thu\u1eadt, h\u00f3a tr\u1ecb v\u00e0 x\u1ea1 tr\u1ecb th\u01b0\u1eddng ch\u1ec9 k\u00e9o d\u00e0i t\u00ednh m\u1ea1ng kh\u00f4ng qu\u00e1 15 th\u00e1ng, khi\u1ebfn kh\u1ed1i u nguy\u00ean b\u00e0o th\u1ea7n kinh \u0111\u1ec7m tr\u1edf th\u00e0nh m\u1ed9t trong nh\u1eefng lo\u1ea1i ung th\u01b0 \u00e1c t\u00ednh nh\u1ea5t hi\u1ec7n nay. Trong c\u1ea3 m\u1ed9t th\u1eadp k\u1ef7, c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 n\u00e3o Glioblastoma g\u1ea7n nh\u01b0 ch\u1ec9 d\u1eadm ch\u00e2n t\u1ea1i ch\u1ed7.<\/p>\n

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\"C\u00e1c<\/div>\n
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T\u1ef7 l\u1ec7 s\u1ed1ng c\u1ee7a b\u1ec7nh nh\u00e2n ung th\u01b0 t\u0103ng g\u1ea5p 5 l\u1ea7n trong th\u1eed nghi\u1ec7m ti\u00eam virus b\u1ea1i li\u1ec7t bi\u1ebfn \u0111\u1ed1i gen<\/p>\n<\/div>\n<\/div>\n

Glioblastoma l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh ung th\u01b0 kh\u00f3 \u0111i\u1ec1u tr\u1ecb b\u1eadc nh\u1ea5t trong t\u1ea5t c\u1ea3 c\u00e1c kh\u1ed1i u n\u00e3o \u00e1c t\u00ednh. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y co gi\u1eadt, \u0111au \u0111\u1ea7u, m\u1edd m\u1eaft v\u00e0 l\u00fa l\u1eabn tr\u01b0\u1edbc khi gi\u1ebft ch\u1ebft b\u1ec7nh nh\u00e2n trong v\u00f2ng 20 th\u00e1ng, ngay c\u1ea3 khi h\u1ecd \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb t\u00edch c\u1ef1c.<\/p>\n

\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n h\u00f3a tr\u1ecb, ph\u1eabu thu\u1eadt ho\u1eb7c x\u1ea1 tr\u1ecb m\u00e0 v\u1eabn t\u00e1i ph\u00e1t, h\u1ecd th\u01b0\u1eddng ch\u1ec9 s\u1ed1ng \u0111\u01b0\u1ee3c d\u01b0\u1edbi 1 n\u0103m. Nh\u01b0ng trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng c\u1ee7a c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1eeb \u0110\u1ea1i h\u1ecdc Duke, th\u1eddi gian s\u1ed1ng cho b\u1ec7nh nh\u00e2n ung th\u01b0 n\u00e3o Glioblastoma \u0111\u00e3 \u0111\u01b0\u1ee3c k\u00e9o d\u00e0i g\u1ea5p 3 l\u1ea7n, nh\u1edd m\u1ed9t li\u1ec7u ph\u00e1p s\u1eed d\u1ee5ng virus b\u1ea1i li\u1ec7t bi\u1ebfn \u0111\u1ed5i gen.<\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 n\u1ed1i m\u1ed9t \u1ed1ng th\u00f4ng t\u1eeb ngo\u00e0i h\u1ed9p s\u1ecd v\u00e0o n\u00e3o b\u1ec7nh nh\u00e2n. Sau \u0111\u00f3, h\u1ecd ti\u00eam tr\u1ef1c ti\u1ebfp v\u00e0o kh\u1ed1i u m\u1ed9t li\u1ec1u l\u01b0\u1ee3ng virus \u0111\u00e3 \u0111\u01b0\u1ee3c t\u00ednh to\u00e1n k\u1ef9 c\u00e0ng.<\/p>\n

T\u1eeb l\u00e2u, vi\u1ec7c s\u1eed d\u1ee5ng virus \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u1ec3 \u00fd. Nhi\u1ec1u lo\u1ea1i virus c\u00f3 ti\u1ec1m n\u0103ng tr\u1edf th\u00e0nh m\u1ed9t c\u00f4ng c\u1ee5 k\u00edch ho\u1ea1t h\u1ec7 mi\u1ec5n d\u1ecbch t\u1ea5n c\u00f4ng c\u00e1c kh\u1ed1i u.<\/p>\n

Trong khi m\u1ed9t s\u1ed1 nh\u00e0 khoa h\u1ecdc Anh m\u1edbi ch\u1ec9 c\u00f3 \u00fd t\u01b0\u1edfng s\u1eed d\u1ee5ng virus Zika \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 n\u00e3o, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u1ee7a \u0110\u1ea1i h\u1ecdc Duke \u0111\u00e3 ti\u1ebfn \u0111\u1ebfn th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean 61 b\u1ec7nh nh\u00e2n, s\u1eed d\u1ee5ng virus b\u1ea1i li\u1ec7t \u0111\u01b0\u1ee3c ch\u1ec9nh s\u1eeda gen.<\/p>\n

K\u1ebft qu\u1ea3 cho th\u1ea5y t\u1ef7 l\u1ec7 s\u1ed1ng trung b\u00ecnh c\u1ee7a h\u1ecd \u0111\u00e3 t\u0103ng l\u00ean 12,5 th\u00e1ng, so v\u1edbi 11,3 th\u00e1ng \u0111\u1ed1i v\u1edbi “nh\u00f3m \u0111\u1ed1i ch\u1ee9ng l\u1ecbch s\u1eed<\/i>“. Nh\u00f3m \u0111\u1ed1i ch\u1ee9ng n\u00e0y l\u00e0 nh\u1eefng ng\u01b0\u1eddi ch\u1ec9 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c bi\u1ec7n ph\u00e1p ti\u00eau chu\u1ea9n nh\u01b0 ph\u1eabu thu\u1eadt, h\u00f3a tr\u1ecb v\u00e0 x\u1ea1 tr\u1ecb. T\u1ea5t c\u1ea3 h\u1ecd \u0111\u1ec1u \u0111\u00e3 t\u1eed vong.<\/p>\n

Ng\u01b0\u1ee3c l\u1ea1i, m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng virus b\u1ea1i li\u1ec7t \u0111\u00e3 t\u0103ng th\u1eddi gian s\u1ed1ng s\u00f3t l\u00ean m\u1ee9c \u1ea5n t\u01b0\u1ee3ng. Debra Puffer, m\u1ed9t b\u1ec7nh nh\u00e2n 61 tu\u1ed5i \u1edf Rome, NY, \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc u nguy\u00ean b\u00e0o th\u1ea7n kinh v\u00e0o n\u0103m 2014.<\/p>\n

Sau khi \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ph\u1eabu thu\u1eadt, h\u00f3a tr\u1ecb v\u00e0 x\u1ea1 tr\u1ecb, b\u1ec7nh ung th\u01b0 c\u1ee7a b\u00e0 v\u1eabn t\u00e1i ph\u00e1t. Puffer \u0111\u00e3 t\u00ecm \u0111\u1ebfn c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc Duke \u0111\u1ec3 tham gia th\u1eed nghi\u1ec7m li\u1ec7u ph\u00e1p virus b\u1ea1i li\u1ec7t. B\u00e0 \u0111\u00e3 s\u1ed1ng s\u00f3t t\u1edbi hai n\u0103m r\u01b0\u1ee1i m\u00e0 kh\u00f4ng h\u1ec1 c\u00f3 bi\u1ec3u hi\u1ec7n t\u00e1i ph\u00e1t.<\/p>\n

Cho t\u1edbi th\u00e1ng 8 n\u0103m ngo\u00e1i, c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 m\u1edbi xu\u1ea5t hi\u1ec7n tr\u1edf l\u1ea1i, nh\u01b0ng Puffer ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c ti\u00eam m\u1ed9t li\u1ec1u virus t\u0103ng c\u01b0\u1eddng. \u1ea2nh ch\u1ee5p n\u00e3o c\u1ee7a b\u00e0 cho th\u1ea5y c\u0103n b\u1ec7nh \u0111\u00e3 m\u1ed9t l\u1ea7n n\u1eefa \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd. “M\u1ecdi th\u1ee9 tr\u00f4ng c\u00f3 v\u1ebb t\u1ed1t \u0111\u1eb9p h\u01a1n<\/i>“, b\u00e0 n\u00f3i. “T\u00f4i \u0111ang t\u1eadn h\u01b0\u1edfng m\u00f9a h\u00e8 c\u1ee7a m\u00ecnh”.<\/i><\/p>\n

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\"C\u00e1c<\/div>\n
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Debra Puffer, m\u1ed9t b\u1ec7nh nh\u00e2n m\u1eafc Glioblastoma \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng nh\u1edd s\u1eed d\u1ee5ng virus b\u1ea1i li\u1ec7t \u0111\u01b0\u1ee3c ch\u1ec9nh s\u1eeda gen<\/p>\n<\/div>\n<\/div>\n

Nh\u00e0 th\u1ea7n kinh h\u1ecdc Annick Desjardins, m\u1ed9t trong nh\u1eefng t\u00e1c gi\u1ea3 ch\u00ednh c\u1ee7a nghi\u00ean c\u1ee9u, cho bi\u1ebft \u0111i\u1ec1u tr\u1ecb ung th\u01b0 n\u00e3o b\u1eb1ng virus b\u1ea1i li\u1ec7t v\u1ec1 c\u01a1 b\u1ea3n gi\u1ed1ng nh\u01b0 c\u00e1c li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch kh\u00e1c \u1edf ch\u1ed7, \u0111a s\u1ed1 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi n\u00f3.<\/p>\n

Nh\u01b0ng m\u1ed9t khi li\u1ec7u ph\u00e1p c\u00f3 hi\u1ec7u qu\u1ea3, k\u1ebft qu\u1ea3 m\u00e0 n\u00f3 mang l\u1ea1i cho nh\u1eefng b\u1ec7nh nh\u00e2n may m\u1eafn n\u00e0y th\u1ef1c s\u1ef1 r\u1ea5t \u1ea5n t\u01b0\u1ee3ng.<\/p>\n

\u0110\u1ec3 c\u1ed1 g\u1eafng t\u0103ng t\u1ef7 l\u1ec7 b\u1ec7nh nh\u00e2n \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111ang ti\u1ebfn h\u00e0nh th\u1eed nghi\u1ec7m giai \u0111o\u1ea1n 2 c\u1ee7a li\u1ec7u ph\u00e1p t\u1ea1i 4 trung t\u00e2m y t\u1ebf kh\u00e1c nhau. Trong \u0111\u00f3, b\u1ec7nh nh\u00e2n ung th\u01b0 n\u00e3o s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p c\u1ea3 h\u00f3a tr\u1ecb l\u1eabn ti\u00eam virus b\u1ea1i li\u1ec7t.<\/p>\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng \u0111ang l\u00ean k\u1ebf ho\u1ea1ch th\u1eed nghi\u1ec7m ti\u00eam virus b\u1ea1i li\u1ec7t bi\u1ebfn \u0111\u1ed5i gen tr\u00ean b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00fa v\u00e0 ung th\u01b0 da.<\/p>\n

Tham kh\u1ea3o\u00a0Washingtonpost<\/i><\/p>\n

B\u00c1O \u0110I\u1ec6N T\u1eec TR\u00cd TH\u1ee8C TR\u1eba<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

B\u1ec7nh nh\u00e2n ung th\u01b0 n\u00e3o d\u1ea1ng Glioblastoma \u0111ang c\u00f3 nhi\u1ec1u c\u01a1 h\u1ed9i h\u01a1n. M\u1ed9t b\u00e1o c\u00e1o v\u1eeba \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Y h\u1ecdc New England tu\u1ea7n tr\u01b0\u1edbc, cho th\u1ea5y k\u1ebft qu\u1ea3 kh\u1ea3 quan c\u1ee7a m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng, trong \u0111\u00f3, c\u00e1c b\u00e1c s\u0129 \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng nh\u1eefng ca b\u1ec7nh ung […]<\/p>\n","protected":false},"author":18,"featured_media":12773,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-12772","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"_links":{"self":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/12772","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=12772"}],"version-history":[{"count":1,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/12772\/revisions"}],"predecessor-version":[{"id":12774,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/12772\/revisions\/12774"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media\/12773"}],"wp:attachment":[{"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=12772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=12772"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/casta.ttud.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=12772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}